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Immunhistochemische und immunelektronenmikroskopischeUntersuchungen zum Vorkommen von dendritischen Zellen im Pankreas der Ratte

Immunohistochemical and immune electron microscopy studies of the occurrence of dendritic cells in the pancreas of the rat

Please always quote using this URN: urn:nbn:de:bvb:20-opus-45689
  • Dendritic cells, first described by STEINMAN and COHN in the mouse spleen and now called lymphoid dendritic cells (LDC), were investigated in the rat pancreas with the monoclonal antibodies 29AI-L. T. and MRC-OX17, which both recognize the la-antigen immunohistochemically and immune electron microscopically. la-positive cells with a dendritic morphology were found in the connective tissue of the cxocrine and endocrine pancreas. Immune e1ectron microscopically, the Ia-antibodies were 10- calized on the cell surface and in sm all vesicles. ADendritic cells, first described by STEINMAN and COHN in the mouse spleen and now called lymphoid dendritic cells (LDC), were investigated in the rat pancreas with the monoclonal antibodies 29AI-L. T. and MRC-OX17, which both recognize the la-antigen immunohistochemically and immune electron microscopically. la-positive cells with a dendritic morphology were found in the connective tissue of the cxocrine and endocrine pancreas. Immune e1ectron microscopically, the Ia-antibodies were 10- calized on the cell surface and in sm all vesicles. A small portion of the la-positive cells showed additional acid phosphatase positivity, i. e. were la-positive macrophages. The other la-positive cells were probably LDC, which may be important in the elimination of foreign antigens, e. g. bacteria and vIruses.show moreshow less

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Metadaten
Author: U. Heusermann, R. Nöthling, M. L. Hansmann, Karin Ulrichs
URN:urn:nbn:de:bvb:20-opus-45689
Document Type:Conference Proceeding
Faculties:Medizinische Fakultät / Klinik und Poliklinik für Allgemein-, Viszeral-, Gefäß- und Kinderchirurgie (Chirurgische Klinik I)
Language:German
Year of Completion:1987
Source:In: Das Pankreas im Verbund der Oberbaucheinheit : 71. Tagung, gehalten in Salzburg vom 9. - 13. Juni 1987 / hrsg. von Klaus Hübner. - Stuttgart u.a.: Fischer, 1987. - (Verhandlungen der Deutschen Gesellschaft für Pathologie ; 71), S. 92 - 95. - ISBN: 3-437-11119-1
Dewey Decimal Classification:6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit
Release Date:2010/08/10
Licence (German):License LogoDeutsches Urheberrecht