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Radionuclide imaging of neurohormonal system of the heart

Please always quote using this URN: urn:nbn:de:bvb:20-opus-149205
  • Heart failure is one of the growing causes of death especially in developed countries due to longer life expectancy. Although many pharmacological and instrumental therapeutic approaches have been introduced for prevention and treatment of heart failure, there are still limitations and challenges. Nuclear cardiology has experienced rapid growth in the last few decades, in particular the application of single photon emission computed tomography (SPECT) and positron emission tomography (PET), which allow non-invasive functional assessment ofHeart failure is one of the growing causes of death especially in developed countries due to longer life expectancy. Although many pharmacological and instrumental therapeutic approaches have been introduced for prevention and treatment of heart failure, there are still limitations and challenges. Nuclear cardiology has experienced rapid growth in the last few decades, in particular the application of single photon emission computed tomography (SPECT) and positron emission tomography (PET), which allow non-invasive functional assessment of cardiac condition including neurohormonal systems involved in heart failure; its application has dramatically improved the capacity for fundamental research and clinical diagnosis. In this article, we review the current status of applying radionuclide technology in non-invasive imaging of neurohormonal system in the heart, especially focusing on the tracers that are currently available. A short discussion about disadvantages and perspectives is also included.show moreshow less

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Metadaten
Author: Xinyu Chen, Rudolf A. Werner, Mehrbod S. Javadi, Yoshifumi Maya, Michael Decker, Constantin Lapa, Ken Herrmann, Takahiro Higuchi
URN:urn:nbn:de:bvb:20-opus-149205
Document Type:Journal article
Faculties:Medizinische Fakultät / Klinik und Poliklinik für Nuklearmedizin
Fakultät für Chemie und Pharmazie / Institut für Pharmazie und Lebensmittelchemie
Language:English
Parent Title (English):Theranostics
Year of Completion:2015
Volume:5
Issue:6
Pagenumber:545-558
Source:Theranostics 5(6), 545-558 (2015). DOI: 10.7150/thno.10900
DOI:https://doi.org/10.7150/thno.10900
Dewey Decimal Classification:6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit
Tag:PET; SPECT; cardiac neurohormonal system; heart failure; nuclear cardiology; radiotracer
Release Date:2018/11/27
Licence (German):License LogoCC BY-NC: Creative-Commons-Lizenz: Namensnennung, Nicht kommerziell 4.0 International