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Cardioventilatory effects of TRH in anesthetized rats: role of the brainstem

Please always quote using this URN: urn:nbn:de:bvb:20-opus-63277
  • Cardioventilator responses were studied in anaesthetized rats after injections of TRH into either the lateral (i.c.v. lat) or the fourth (i.c.v. IV) cerebral ventricles. TRH induced a morerapid hypertensive effect i.c.v. IV than i.c.v. lat. Blocking of the cerebral aqueduct abolished the hypertensive and tachypnoeic effects of TRH i.c.v. lat but not those of TRH i.c.v. IV. It is concluded that TRH increased blood pressure and ventilation rate via brain stem structures close to the fourtli ventricle.

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Author: I. Paakkari, M-L. Nurminen, Anna-Leena Sirén
Document Type:Journal article
Faculties:Medizinische Fakultät / Neurochirurgische Klinik und Poliklinik
Year of Completion:1986
Source:In: European Journal of Pharmacology (1986) 122, 131-134.
Dewey Decimal Classification:6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit
GND Keyword:Neurobiologie
Tag:Brain stem; Cardiovascular; TRH; Ventilation
Release Date:2012/08/09
Licence (German):License LogoDeutsches Urheberrecht