Oncolytic Virotherapy of Canine and Feline Cancer
Please always quote using this URN: urn:nbn:de:bvb:20-opus-119753
- Cancer is the leading cause of disease-related death in companion animals such as dogs and cats. Despite recent progress in the diagnosis and treatment of advanced canine and feline cancer, overall patient treatment outcome has not been substantially improved. Virotherapy using oncolytic viruses is one promising new strategy for cancer therapy. Oncolytic viruses (OVs) preferentially infect and lyse cancer cells, without causing excessive damage to surrounding healthy tissue, and initiate tumor-specific immunity. The current review describes theCancer is the leading cause of disease-related death in companion animals such as dogs and cats. Despite recent progress in the diagnosis and treatment of advanced canine and feline cancer, overall patient treatment outcome has not been substantially improved. Virotherapy using oncolytic viruses is one promising new strategy for cancer therapy. Oncolytic viruses (OVs) preferentially infect and lyse cancer cells, without causing excessive damage to surrounding healthy tissue, and initiate tumor-specific immunity. The current review describes the use of different oncolytic viruses for cancer therapy and their application to canine and feline cancer.…
Author: | Ivaylo Gentschev, Sadeep S. Patil, Ivan Petrov, Joseph Cappello, Marion Adelfinger, Aladar A. Szalay |
---|---|
URN: | urn:nbn:de:bvb:20-opus-119753 |
Document Type: | Journal article |
Faculties: | Fakultät für Chemie und Pharmazie / Lehrstuhl für Biochemie |
Language: | English |
Parent Title (English): | Viruses |
Year of Completion: | 2014 |
Volume: | 6 |
Issue: | 5 |
Pagenumber: | 2122-2137 |
Source: | Viruses 2014, 6, 2122-2137; doi:10.3390/v6052122 |
DOI: | https://doi.org/10.3390/v6052122 |
Dewey Decimal Classification: | 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit |
Tag: | cancer; canine and feline cancer therapy; oncolysis; oncolytic virus |
Release Date: | 2015/11/12 |
Licence (German): | CC BY: Creative-Commons-Lizenz: Namensnennung |