Confirmation of the localization of the human recombination activating gene 1 (RAG1) to chromosome 11p13

Please always quote using this URN: urn:nbn:de:bvb:20-opus-59136
  • The human recombination activating gene 1 (RAGl) has previously been mapped to chromosomes 14q and 11 p. Here we confirm the chromosome 11 assignment by two independent approaches: autoradiographic and fluorescence in situ hybridization to metaphase spreads and analysis of human-hamster somatic cell hybrid DNA by the polymerase chain reaction (PCR) and Southern blotting. Our results unequivocally localize RAG1 to llp13.

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Author: Klaus Schwarz, Horst Hameister, Manfred Gessler, Karl-Heinz Grzeschik, Thomas E. Hansen-Hagge, Claus R. Bartram
Document Type:Journal article
Faculties:Fakultät für Biologie / Theodor-Boveri-Institut für Biowissenschaften
Year of Completion:1994
Source:In: Human Genetics (1994) 93, S. 215 - 217.
Dewey Decimal Classification:5 Naturwissenschaften und Mathematik / 57 Biowissenschaften; Biologie / 570 Biowissenschaften; Biologie
GND Keyword:Biochemie
Release Date:2011/08/18
Licence (German):License LogoDeutsches Urheberrecht