Characterization of a chromosomal mutant that blocks hemolysin excretion in Escherichia coli

Please always quote using this URN: urn:nbn:de:bvb:20-opus-59534
  • We analyzed an Escherichia coli strain which harbours a chromosomal mutation that blocks the hemolysin excretion. Compartmentation studies showed that hemolysin accumulates in the cytoplasm and not in the periplasm. The mutation did not affect the SDS-PAGE protein pattern of the outer membrane, although some alterations were apparent in the periplasmic protein pattern. The mutant strain, E. coli Hsb-1 also failed to export a cloned fimbrial adhesin. The mutation maps in the min. 3.5 of the E. coli genetic map.

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Author: F. Munoa, Jörg Hacker, A. Juarez
Document Type:Journal article
Faculties:Medizinische Fakultät / Institut für Molekulare Infektionsbiologie
Year of Completion:1988
Source:In: FEMS microbiology letters (1988) 56, 167-172.
Dewey Decimal Classification:5 Naturwissenschaften und Mathematik / 57 Biowissenschaften; Biologie / 570 Biowissenschaften; Biologie
GND Keyword:Infektionsbiologie
Tag:Escherichia coli; Hemolysin excretion; Mutant
Release Date:2011/11/22
Licence (German):License LogoDeutsches Urheberrecht