Injection of thyrotropin releasing hormone into the locus coeruleus increases blood pressure
Please always quote using this URN: urn:nbn:de:bvb:20-opus-72894
- Thyrotropin releasing hormone (TRH), 10 pmol kg-1 injected in the region of locus coeruleus, caused a rapid (within 1 min) rise of mean arterial pressure in the urethane- naesthetized rat. No clear-cut effects in heart rate or ventilation were observed. When TRH was injected into the lateral ventricle, a dose more than 10-fold higher was required to achieve a comparable rise in arterial pressure. It is concluded that TRH may have a physiological rote in centrat cardiovascular regulation.
| Author: | I. Paakkari, Anna-Leena Sirén, M.-L. Nurminen, M. Svartström-Fraser |
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| URN: | urn:nbn:de:bvb:20-opus-72894 |
| Document Type: | Journal article |
| Faculties: | Medizinische Fakultät / Neurochirurgische Klinik und Poliklinik |
| Language: | English |
| Year of Completion: | 1987 |
| Source: | In: European Heart Journal, 1987, Suppl. B, 8, S.147-151. |
| Dewey Decimal Classification: | 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit |
| GND Keyword: | Thyreotropin-Releasinghormon; Blutdruck; Locus coeruleus |
| Tag: | TRH; blood pressure; locus coeruleus |
| Release Date: | 2014/06/02 |
| Licence (German): |  Deutsches Urheberrecht |