Hypoxia independent drivers of melanoma angiogenesis

Please always quote using this URN: urn:nbn:de:bvb:20-opus-125586
  • Tumor angiogenesis is a process which is traditionally regarded as the tumor’s response to low nutrient supply occurring under hypoxic conditions. However, hypoxia is not a pre-requisite for angiogenesis. The fact that even single tumor cells or small tumor cell aggregates are capable of attracting blood vessels reveals the early metastatic capability of tumor cells. This review sheds light on the hypoxia-independent mechanisms of tumor angiogenesis in melanoma.

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Author: Svenja Meierjohann
Document Type:Journal article
Faculties:Medizinische Fakultät / Theodor-Boveri-Institut für Biowissenschaften
Parent Title (English):Frontiers in Oncology
Year of Completion:2015
Source:Frontiers in Oncology 5:102. doi: 10.3389/fonc.2015.00102
Dewey Decimal Classification:6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit
Tag:NF-κB; angiogenesis; hypoxia-independent; melanoma; reactive oxygen species
Release Date:2016/02/02
Collections:Open-Access-Publikationsfonds / Förderzeitraum 2015
Licence (German):License LogoCC BY: Creative-Commons-Lizenz: Namensnennung