Septic Vs Colonizing Group B Streptococci Differentially Regulate Inflammation and Apoptosis in Human Coronary Artery Endothelial Cells - a Pilot Study

Please always quote using this URN: urn:nbn:de:bvb:20-opus-125596
  • In this pilot study, we exemplify differences between a septic and a colonizing GBS strain during their interaction with Endothelial Cells by evaluating cytokine levels, surface and apoptosis-related molecules. These preliminary results indicate that in vitro infection using an exemplary septic GBS strain results in diminished activation of the innate immune response.

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Author: Claudia Loeffler, Jürgen Loeffler, Anna Kobsar, Christian P. Speer, Martin Eigenthaler
Document Type:Journal article
Faculties:Medizinische Fakultät / Kinderklinik und Poliklinik
Medizinische Fakultät / Institut für Klinische Biochemie und Pathobiochemie
Medizinische Fakultät / Medizinische Klinik und Poliklinik II
Parent Title (English):Journal of Pediatrics and Neonatal Care
Year of Completion:2015
Source:Journal of Pediatrics and Neonatal Care 2015, 2(2): 00064. DOI: 10.15406/jpnc.2015.02.00064
Dewey Decimal Classification:6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit
Tag:apoptosis; early onset sepsis; endothelial cells; inflammation; innate immunity; streptococci
Release Date:2016/02/02
Collections:Open-Access-Publikationsfonds / Förderzeitraum 2015
Licence (German):License LogoCC BY: Creative-Commons-Lizenz: Namensnennung