Copper‐Catalyzed Oxidative Cross‐Coupling of Electron‐Deficient Polyfluorophenylboronate Esters with Terminal Alkynes

Please always quote using this URN: urn:nbn:de:bvb:20-opus-224362
  • We report herein a mild procedure for the copper‐catalyzed oxidative cross‐coupling of electron‐deficient polyfluorophenylboronate esters with terminal alkynes. This method displays good functional group tolerance and broad substrate scope, generating cross‐coupled alkynyl(fluoro)arene products in moderate to excellent yields. Thus, it represents a simple alternative to the conventional Sonogashira reaction.

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Author: Zhiqiang Liu, Yudha P. Budiman, Ya‐Ming Tian, Alexandra Friedrich, Mingming Huang, Stephen A. Westcott, Udo Radius, Todd B. Marder
Document Type:Journal article
Faculties:Fakultät für Chemie und Pharmazie / Institut für Anorganische Chemie
Parent Title (English):Chemistry – A European Journal
Year of Completion:2020
First Page:17267
Last Page:17274
Source:Chemistry – A European Journal 2020, 26(71):17267-17274. DOI: 10.1002/chem.202002888
Dewey Decimal Classification:5 Naturwissenschaften und Mathematik / 54 Chemie / 540 Chemie und zugeordnete Wissenschaften
Tag:Sonogashira reaction; boronate esters; coupling reactions; fluorine; fluoroarenes
Release Date:2021/12/15
Licence (German):License LogoCC BY: Creative-Commons-Lizenz: Namensnennung 4.0 International