Nucleotide sequence of the sfaA gene coding for the S fimbrial protein subunit of Escherichia coli
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- The sfaA gene of the uropathogenic Escherichia coli 06 strain 536, which is responsible for the determination of the S fimbrial protein subunit, was sequenced. The structural gene codes for a polypeptide of 180 amino acids including a 24-residue N-terminal signal sequence. A size of 15.95 kDa was calculated for the processed SfaA protein. The nucleotide and deduced amino acid sequences show significant homology to those of the F1C fimbria and, to a lesser extent, of the mannose- sensitive hemagglutinating fimbria (FimA, PilA). Only weekThe sfaA gene of the uropathogenic Escherichia coli 06 strain 536, which is responsible for the determination of the S fimbrial protein subunit, was sequenced. The structural gene codes for a polypeptide of 180 amino acids including a 24-residue N-terminal signal sequence. A size of 15.95 kDa was calculated for the processed SfaA protein. The nucleotide and deduced amino acid sequences show significant homology to those of the F1C fimbria and, to a lesser extent, of the mannose- sensitive hemagglutinating fimbria (FimA, PilA). Only week homology toP fimbriae subunits (F72 , Pap) was found.…
Autor(en): | T. Schmoll, Jörg Hacker, W. Goebel |
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URN: | urn:nbn:de:bvb:20-opus-59480 |
Dokumentart: | Artikel / Aufsatz in einer Zeitschrift |
Institute der Universität: | Medizinische Fakultät / Institut für Molekulare Infektionsbiologie |
Sprache der Veröffentlichung: | Englisch |
Erscheinungsjahr: | 1987 |
Originalveröffentlichung / Quelle: | In: FEMS microbiology letters (1987) 41, 229-235. |
Allgemeine fachliche Zuordnung (DDC-Klassifikation): | 5 Naturwissenschaften und Mathematik / 57 Biowissenschaften; Biologie / 570 Biowissenschaften; Biologie |
Normierte Schlagworte (GND): | Infektionsbiologie |
Freie Schlagwort(e): | (Nucleotide sequence; Escherichia coli; Fimbria; sfaA gene) |
Datum der Freischaltung: | 20.11.2011 |
Lizenz (Deutsch): | Deutsches Urheberrecht |