Recombinant human interleukin 2 acts as a B cell growth and differentiation promoting factor
Please always quote using this URN: urn:nbn:de:bvb:20-opus-34132
- Human B cells appropriately activated by a B cell mitogen are rendered susceptible to human Interleukin 2 (IL-2) as demonstrated with recombinant human IL-2 (rec. h IL-2). They show increased proliferation and drastically enhanced immunoglobulin secretion. Susceptibility to IL-2 is accompanied with the expression of the IL-2 receptor (Tac antigen) on B cells. The data suggest that IL-2 is one of the lymphokines directly involved in the activation of B lymphocytes.
| Author: | F. Emmrich, Heidrun Moll, Markus M. Simon |
|---|---|
| URN: | urn:nbn:de:bvb:20-opus-34132 |
| Document Type: | Journal article |
| Faculties: | Medizinische Fakultät / Institut für Molekulare Infektionsbiologie |
| Language: | English |
| Year of Completion: | 1985 |
| Source: | In: Immunobiol. (1985) 169, 97-102. |
| Dewey Decimal Classification: | 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit |
| Release Date: | 2009/08/28 |