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Erscheinungsjahr
- 1987 (1)
Dokumenttyp
Sprache
- Englisch (1)
Schlagworte
- Locus coeruleus (1) (entfernen)
Institut
- Neurochirurgische Klinik und Poliklinik (1) (entfernen)
Thyrotropin releasing hormone (TRH), 10 pmol kg-1 injected in the region of locus coeruleus, caused a rapid (within 1 min) rise of mean arterial pressure in the urethane- naesthetized rat. No clear-cut effects in heart rate or ventilation were observed. When TRH was injected into the lateral ventricle, a dose more than 10-fold higher was required to achieve a comparable rise in arterial pressure. It is concluded that TRH may have a physiological rote in centrat cardiovascular regulation.