TY  - JOUR
A1  - Dreischulte, Tobias
A1  - Sanftenberg, Linda
A1  - Hennigs, Philipp
A1  - Zöllinger, Isabel
A1  - Schwaiger, Rita
A1  - Floto, Caroline
A1  - Sebastiao, Maria
A1  - Kühlein, Thomas
A1  - Hindenburg, Dagmar
A1  - Gagyor, Ildikó
A1  - Wildgruber, Domenika
A1  - Hausen, Anita
A1  - Janke, Christian
A1  - Hölscher, Michael
A1  - Teupser, Daniel
A1  - Gensichen, Jochen
T1  - Detecting medication risks among people in need of care: performance of six instruments
T2  - International Journal of Environmental Research and Public Health
N2  - Introduction: Numerous tools exist to detect potentially inappropriate medication (PIM) and potential prescribing omissions (PPO) in older people, but it remains unclear which tools may be most relevant in which setting. Objectives: This cross sectional study compares six validated tools in terms of PIM and PPO detection. Methods: We examined the PIM/PPO prevalence for all tools combined and the sensitivity of each tool. The pairwise agreement between tools was determined using Cohen’s Kappa. Results: We included 226 patients in need of care (median (IQR age 84 (80–89)). The overall PIM prevalence was 91.6 (95% CI, 87.2–94.9)% and the overall PPO prevalence was 63.7 (57.1–69.9%)%. The detected PIM prevalence ranged from 76.5%, for FORTA-C/D, to 6.6% for anticholinergic drugs (German-ACB). The PPO prevalences for START (63.7%) and FORTA-A (62.8%) were similar. The pairwise agreement between tools was poor to moderate. The sensitivity of PIM detection was highest for FORTA-C/D (55.1%), and increased to 79.2% when distinct items from STOPP were added. Conclusion: Using a single screening tool may not have sufficient sensitivity to detect PIMs and PPOs. Further research is required to optimize the composition of PIM and PPO tools in different settings.
KW  - inappropriate medication
KW  - prescribing omission
KW  - nursing home residents
KW  - polypharmacy
KW  - adverse drug reaction
Y1  - 2023
UR  - https://opus.bibliothek.uni-wuerzburg.de/opus4-wuerzburg/frontdoor/index/index/docId/30492
UR  - https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-304921
SN  - 1660-4601
VL  - 20
IS  - 3
ER  -