@article{WernerPoppFichtneretal.2022,
  author    = {Werner, Anne and Popp, Maria and Fichtner, Falk and Holzmann-Littig, Christopher and Kranke, Peter and Steckelberg, Anke and L{\"u}hnen, Julia and Redlich, Lisa Marie and Dickel, Steffen and Grimm, Clemens and Moerer, Onnen and Nothacker, Monika and Seeber, Christian},
  title     = {COVID-19 intensive care — Evaluation of public information sources and current standards of care in German intensive care units: a cross sectional online survey on intensive care staff in Germany},
  series = {Healthcare},
  volume    = {10},
  journal   = {Healthcare},
  number    = {7},
  issn      = {2227-9032},
  doi       = {10.3390/healthcare10071315},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-281865},
  year      = {2022},
  abstract  = {Backround: In February 2021, the first formal evidence and consensus-based (S3) guidelines for the inpatient treatment of patients with COVID-19 were published in Germany and have been updated twice during 2021. The aim of the present study is to re-evaluate the dissemination pathways and strategies for ICU staff (first evaluation in December 2020 when previous versions of consensus-based guidelines (S2k) were published) and question selected aspects of guideline adherence of standard care for patients with COVID-19 in the ICU. Methods: We conducted an anonymous online survey among German intensive care staff from 11 October 2021 to 11 November 2021. We distributed the survey via e-mail in intensive care facilities and requested redirection to additional intensive care staff (snowball sampling). Results: There was a difference between the professional groups in the number, selection and qualitative assessment of information sources about COVID-19. Standard operating procedures were most frequently used by all occupational groups and received a high quality rating. Physicians preferred sources for active information search (e.g., medical journals), while nurses predominantly used passive consumable sources (e.g., every-day media). Despite differences in usage behaviour, the sources were rated similarly in terms of the quality of the information on COVID-19. The trusted organizations have not changed over time. The use of guidelines was frequently stated and highly recommended. The majority of the participants reported guideline-compliant treatment. Nevertheless, there were certain variations in the use of medication as well as the criteria chosen for discontinuing non-invasive ventilation (NIV) compared to guideline recommendations. Conclusions: An adequate external source of information for nursing staff is lacking, the usual sources of physicians are only appropriate for the minority of nursing staff. The self-reported use of guidelines is high.},
  language  = {en}
}
@article{BalafoutasWoeckelWulffetal.2020,
  author    = {Balafoutas, Dimitrios and W{\"o}ckel, Achim and Wulff, Christine and Joukhadar, Ralf},
  title     = {Implementation of robotic gynecological surgery in a German University Hospital: patient safety after 110 procedures},
  series = {Archives of Gynecology and Obstetrics},
  volume    = {302},
  journal   = {Archives of Gynecology and Obstetrics},
  issn      = {0932-0067},
  doi       = {10.1007/s00404-020-05751-8},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-232650},
  pages     = {1381-1388},
  year      = {2020},
  abstract  = {Purpose Robotic surgery represents the latest development in the field of minimally invasive surgery and offers many technical advantages. Despite the higher costs, this novel approach has been applied increasingly in gynecological surgery. Regarding the implementation of a new operative method; however, the most important factor to be aware of is patient safety. In this study, we describe our experience in implementing robotic surgery in a German University Hospital focusing on patient safety after 110 procedures. Methods We performed a retrospective analysis of 110 consecutive robotic procedures performed in the University Hospital of W{\"u}rzburg between June 2017 and September 2019. During this time, 37 patients were treated for benign general gynecological conditions, 27 patients for gynecological malignancies, and 46 patients for urogynecological conditions. We evaluated patient safety through standardized assessment of intra- and postoperative complications, which were categorized according to the Clavien-Dindo classification. Results No complications were recorded in 90 (81.8\%) operations. We observed Clavien-Dindo grade I complications in 8 (7.3\%) cases, grade II complications in 5 (4.5\%) cases, grade IIIa complications in 1 case (0.9\%), and grade IIIb complications in 6 (5.5\%) cases. No conversion to laparotomy or blood transfusion was needed. Conclusion Robotic surgery could be implemented for complex gynecological operations without relevant problems and was accompanied by low complication rates.},
  language  = {en}
}
@article{HillmannWiedmannFraseretal.2015,
  author    = {Hillmann, Steffi and Wiedmann, Silke and Fraser, Alec and Baeza, Juan and Rudd, Anthony and Norrving, Bo and Asplund, Kjell and Niewada, Maciej and Dennis, Martin and Hermanek, Peter and Wolfe, Charles D. A. and Heuschmann, Peter U.},
  title     = {Temporal changes in the quality of acute stroke care in five national audits across Europe},
  series = {BioMed Research International},
  volume    = {2015},
  journal   = {BioMed Research International},
  number    = {432497},
  doi       = {10.1155/2015/432497},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-149059},
  year      = {2015},
  abstract  = {Background. Data on potential variations in delivery of appropriate stroke care over time are scarce. We investigated temporal changes in the quality of acute hospital stroke care across five national audits in Europe over a period of six years. Methods. Data were derived from national stroke audits in Germany, Poland, Scotland, Sweden, and England/Wales/Northern Ireland participating within the European Implementation Score (EIS) collaboration. Temporal changes in predefined quality indicators with comparable information between the audits were investigated. Multivariable logistic regression analyses were performed to estimate adherence to quality indicators over time. Results. Between 2004 and 2009, individual data from 542,112 patients treated in 538 centers participating continuously over the study period were included. In most audits, the proportions of patients who were treated on a SU, were screened for dysphagia, and received thrombolytic treatment increased over time and ranged from 2-fold to almost 4-fold increase in patients receiving thrombolytic therapy in 2009 compared to 2004. Conclusions. A general trend towards a better quality of stroke care defined by standardized quality indicators was observed over time. The association between introducing a specific measure and higher adherence over time might indicate that monitoring of stroke care performance contributes to improving quality of care.},
  language  = {en}
}
@article{EhrenfeldHerbortButz2013,
  author    = {Ehrenfeld, Stephan and Herbort, Oliver and Butz, Martin V.},
  title     = {Modular neuron-based body estimation: maintaining consistency over different limbs, modalities, and frames of reference},
  series = {Frontiers in Computational Neuroscience},
  volume    = {7},
  journal   = {Frontiers in Computational Neuroscience},
  number    = {148},
  doi       = {10.3389/fncom.2013.00148},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-122253},
  year      = {2013},
  abstract  = {This paper addresses the question of how the brain maintains a probabilistic body state estimate over time from a modeling perspective. The neural Modular Modality Frame (nMMF) model simulates such a body state estimation process by continuously integrating redundant, multimodal body state information sources. The body state estimate itself is distributed over separate, but bidirectionally interacting modules. nMMF compares the incoming sensory and present body state information across the interacting modules and fuses the information sources accordingly. At the same time, nMMF enforces body state estimation consistency across the modules. nMMF is able to detect conflicting sensory information and to consequently decrease the influence of implausible sensor sources on the fly. In contrast to the previously published Modular Modality Frame (MMF) model, nMMF offers a biologically plausible neural implementation based on distributed, probabilistic population codes. Besides its neural plausibility, the neural encoding has the advantage of enabling (a) additional probabilistic information flow across the separate body state estimation modules and (b) the representation of arbitrary probability distributions of a body state. The results show that the neural estimates can detect and decrease the impact of false sensory information, can propagate conflicting information across modules, and can improve overall estimation accuracy due to additional module interactions. Even bodily illusions, such as the rubber hand illusion, can be simulated with nMMF. We conclude with an outlook on the potential of modeling human data and of invoking goal-directed behavioral control.},
  language  = {en}
}
@article{WiedmannHeuschmannHillmannetal.2014,
  author    = {Wiedmann, Silke and Heuschmann, Peter U. and Hillmann, Steffi and Busse, Otto and Wiethoelter, Horst and Walter, Georg M. and Seidel, Guenter and Misselwitz, Bjoern and Janssen, Alfred and Berger, Klaus and Burmeister, Christoph and Matthias, Christine and Kolominsky-Rabas, Peter and Hermanek, Peter},
  title     = {The Quality of Acute Stroke Care-an Analysis of Evidence-Based Indicators in 260 000 Patients},
  series = {Deutsches {\"A}rzteblatt International},
  volume    = {111},
  journal   = {Deutsches {\"A}rzteblatt International},
  number    = {45},
  issn      = {1866-0452},
  doi       = {10.3238/arztebl.2014.0759},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-114747},
  pages     = {759-765},
  year      = {2014},
  abstract  = {Background: Stroke patients should be cared for in accordance with evidence-based guidelines. The extent of implementation of guidelines for the acute care of stroke patients in Germany has been unclear to date. Methods: The regional quality assurance projects that cooperate in the framework of the German Stroke Registers Study Group (Arbeitsgemeinschaft Deutscher Schlaganfall-Register, ADSR) collected data on the care of stroke patients in 627 hospitals in 2012. The quality of the acute hospital care of patients with stroke or transient ischemic attack (TIA) was assessed on the basis of 15 standardized, evidence-based quality indicators and compared across the nine participating regional quality assurance projects. Results: Data were obtained on more than 260 000 patients nationwide. Intravenous thrombolysis was performed in 59.7\% of eligible ischemic stroke patients patients (range among participating projects, 49.7-63.6\%). Dysphagia screening was documented in 86.2\% (range, 74.8-93.1\%). For the following indicators, the defined targets were not reached for all of Germany: antiaggregation within 48 hours, 93.4\% (range, 86.6-96.4\%); anticoagulation for atrial fibrillation, 77.6\% (range, 72.4-80.1\%); standardized dysphagia screening, 86.2\% (range, 74.8-93.1\%); oral and written information of the patients or their relatives, 86.1\% (range, 75.4-91.5\%). The rate of patients examined or treated by a speech therapist was in the target range. Conclusion: The defined targets were reached for most of the quality indicators. Some indicators, however, varied widely across regional quality assurance projects. This implies that the standardization of care for stroke patients in Germany has not yet been fully achieved.},
  language  = {en}
}