@article{ErnsbergerSendtnerRohrer1989, author = {Ernsberger, Uwe and Sendtner, Michael and Rohrer, Hermann}, title = {Proliferation and differentiation of embryonic chick sympathetic neurons: Effects of ciliary neurotropic factor.}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-31721}, year = {1989}, abstract = {At early developmental stages (embryonic day 7, E7), chick paravertebral sympathetic ganglia contain a cell population that divides in culture while expressing various neuronal properties. In an attempt to identify factors that control neuronal proliferation, we found that ciliary neurotrophic factor (CNTF) specifically inhibits the proliferation of those cells expressing neuronal markers. In addition, CNTF affects the differentiation of sympathetic ganglion cells by inducing the expression of vasoactive intestinal peptide immunoreactivity (VIP-IR). After 1 day in culture, tyrosine hydroxylase immunoreactivity (TH-I R) was expressed by about 86\% of the cells whereas VIP-IR was virtually absent. In the presence of CNTF, 50\%-60\% of the cells expressed VIP-IR after 4 days in culture; however, none of the cells expressed VIP-IR in the absence of CNTF. These results, and the demonstration of cells that express both VIP and TH-IR, indicate that VIP is induced in cells that initially express tyrosine hydroxylase. The findings suggest a potential role for CNTF as a factor affecting the proliferation and differentiation of developing sympathetic neurons.}, language = {en} } @article{GrafeLinsenmair1989, author = {Grafe, U. and Linsenmair, Karl Eduard}, title = {Protogynous sex change in the Reed Frog: Hyperolius viridiflavus}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-30990}, year = {1989}, abstract = {Observations on captive reed frogs Hyperolius viridijlavus ommatostictus showed that seven out of 24 females changed into males. Sex change occurred without any hormone treatment and resulted in completely functional males. The adaptive value is discussed in terms of maximizing life-time reproductive success. Hyperolius r. ommatostictus is the first amphibian known to show functional sex reversal.}, language = {en} } @inproceedings{KruegerHeller1989, author = {Kr{\"u}ger, Hans-Peter and Heller, Dieter}, title = {Psychomotorische Effekte von Alkohol}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-87079}, year = {1989}, abstract = {No abstract available.}, subject = {Psychomotorik}, language = {de} } @article{KreftFunkeSchlesingeretal.1989, author = {Kreft, J{\"u}rgen and Funke, D. and Schlesinger, R. and Lottspeich, F. and Goebel, Werner}, title = {Purification and characterization of cytolysins from Listeria monocytogenes serovar 4b and Listeria ivanovii}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-47036}, year = {1989}, abstract = {Several exoproteins from Listeria monocytogenes serovar 4b (NCTC 10527) and Listeria ivanovii (ATCC) 19119, SLCC 2379), respectively, have been purified to homogeneity by thiol-disulfide exchange chromatography and gel filtration. Both strains produce a haemolytic/cytolytic protein of Mr 58 kDa, which has all the properties of a SH-activated cytolysin, the prototype of which is streptolysin 0 (SLO), and this protein has therefore heen termed Iisteriolysin 0 (LLO). In addition a protein of Mr 24 kDa from culture supernatants of L. ivanovii co-purified withLLO. The N-terminal aminoacid sequences of both proteins from L. ivanovii have been determined. By mutagenesis with transposons of Gram-positive origin (Tn916 and TnI545), which have been introduced via conjugation into L. ivanovii, several phenotypic mutants (altered haemolysis on sheep blood agar or lecithinase-negative) were obtained. Results on the properties of these muntants will he presented.}, language = {en} } @misc{Ruhe1989, author = {Ruhe, Ernstpeter}, title = {Rachid Boujedra: Bio-bibliographie}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-36970}, year = {1989}, abstract = {No abstract available}, language = {de} } @article{ReddingtonKlotzLohseetal.1989, author = {Reddington, M. and Klotz, Karl-Norbert and Lohse, M. J. and Hietel, B.}, title = {Radiation inactivation analysis of the A\(_1\) adenosine receptor: decrease in radiation inactivation size in the presence of guanine nucleotide}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-60318}, year = {1989}, abstract = {Radiation inactivation analysis of the binding of the A1 adenosine receptor antagonist, 8-cyclopentyl-1,3-dipropylxanthine to rat brain membranes yielded a radiation inactivation size of 58 kDa. In the presence of GTPyS this was reduced to 33 kDa, in good agreement with the size of the ligand-binding subunit detected after photoaffinity labelling. The data indicate that the structural association of A\(_1\) adenosine receptors with G-protein components is altered in situ in the presence of guanine nucleotides.}, subject = {Toxikologie}, language = {en} } @article{BorasioJohnWittinghoferetal.1989, author = {Borasio, Gian Domenico and John, Jacob and Wittinghofer, Alfred and Barde, Yves-Alain and Sendtner, Michael and Heumann, Rolf}, title = {ras p21 protein promotes survival and fiber outgrowth of cultured embryonic neurons}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-32621}, year = {1989}, abstract = {Although evidence obtained with the PC12 cell line has suggested a role for the ras oncogene proteins in the signal transduction of nerve growth factor-mediated fiber outgrowth, little is known about the signal transduction mechanisms involved in the neuronal response to neurotrophic factors in nontransformed cells. We report here that the oncogene protein T24-ras, when introduced into the cytoplasm of freshly dissociated chick embryonic neurons, promotes the in vitro survival and neurite outgrowth of nerve growth factor-responsive dorsal rootganglion neurons, brain-derived neurotrophic factor-responsive nodose ganglion neurons, and ciliary neuronotrophic factor-responsive ciliary ganglion neurons. The proto-oncogene product c-Ha-ras also promotes neuronal survival, albeit less strongly. No effect could be observed with truncated counterparts of T24-ras and c-Ha-ras lacking the 23 C-terminal amino acids including the membrane-an-choring, palmityl-accepting cysteine. These results sug-gest a generalized involvement of ras or ras-like proteins in the intracellular signal transduction pathway for neurotrophic factors.}, language = {en} } @article{BaumhauerBuscheSponholz1989, author = {Baumhauer, Roland and Busche, Detlef and Sponholz, Barbara}, title = {Reliefgeschichte und Pal{\"a}oklima des saharischen Ost-Niger}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-55378}, year = {1989}, abstract = {Der gr{\"o}ßte Teil des zentralsaharischen Reliefs ist unter dem Einfluß nicht-arider Klimate gebildet worden. Andererseits gab es im Pleistoz{\"a}n {\"a}olisch gepr{\"a}gte aride Phasen, die extremer als heutige gewesen sind. Der Kenntnisstand zur Reliefgeschichte erlaubt es, daraus die Grundz{\"u}ge der Klimageschichte eines großen Teils der s{\"u}dlich-zentralen Sahara abzuleiten.}, subject = {Geographie}, language = {de} } @incollection{Wegstein1989, author = {Wegstein, Werner}, title = {Reminiszenz an Johann von Paltz in einer Trierer Klosterpredigtsammlung}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-41495}, publisher = {Universit{\"a}t W{\"u}rzburg}, year = {1989}, abstract = {No abstract available}, subject = {Mittelhochdeutsch / Literatur ; Textgeschichte / Geschichte <800-1500>}, language = {de} } @inproceedings{BossertMeilerLaessleetal.1989, author = {Bossert, Sabine and Meiler, Caroline and Laessle, Reinhold and Ellgring, Heiner and Pirke, Karl-Martin}, title = {Responses to visual perception of food in eating disorders}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-58762}, year = {1989}, abstract = {No abstract available}, subject = {Psychologie}, language = {en} } @article{SchneiderSchauliesLiebertBaczkoetal.1989, author = {Schneider-Schaulies, Sibylle and Liebert, U. G. and Baczko, K. and Cattaneo, R. and Billeter, M. and ter Meulen, V.}, title = {Restriction of measles virus gene expression in acute and subacute encephalitis in Lewis rats}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-62266}, year = {1989}, abstract = {No abstract available}, subject = {Virologie}, language = {en} } @misc{ParodiLutzColaccietal.1989, author = {Parodi, S. and Lutz, Werner K. and Colacci, A. and Mazzullo, M. and Taningher, M. and Grilli, S.}, title = {Results of animal studies suggest a nonlinear dose-response relationship for benzene effects}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-60843}, year = {1989}, abstract = {Considering the very large industrial usage of benzene, studies in risk assessment aimed at the evaluation of carcinogenic risk at low Ievels of exposure are important. Animal data can offer indications about what could happen in humans and provide more diverse information than epidemiological data with respect to doseresponse consideration. We have considered experiments investigating metabolism, short·term genotoxicity tests, DNA adduct formation, and carcinogenicity long-term tests. According to the different experiments, a Saturation of benzene metabolism and benzene effects in terms of genotoxicity seems evident above 30 to 100 ppm. Below 30 to 60 ppm the initiating effect ofbenzene seems tobe linear fora large intervaJ ofdosages, at least judging from DNA adduct formation. Potentiallack of a promoting effect of benzene (below 10 ppm) could generate a sublinear response at nontox.ic levels of ex.posure. This possibility was suggested by epidemiological data in humans and is not confirmed or excluded by our observations with animals.}, subject = {Toxikologie}, language = {en} } @article{HackerGadebergOrskov1989, author = {Hacker, J{\"o}rg and Gadeberg, Ole V. and Orskov, Ida}, title = {Role of alpha-Hemolysin for the in vitro Phagocytosis and intracellular killing of Escherichia coli}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-73019}, year = {1989}, abstract = {The_role of a-hemolysin for the elimination of Eschericbia coli by phagocyres in vitro was investigated using sets of isogenic strains which included wild-type a -hemolyric srrains, derived strains with a reduced production of a-hemolysin and derived nonhemolytic strains. Phagocyrosis and intracellular killing of the bacteria by human blood granulocytes or monocytes were measured using growth inhibition rechniques. a-hemolytic strains were phagocytosed and killed ro a Jesser extent than isogenic strains with a reduced production of o:hemoJysin and isogenic nonhemolytic strains. The results obrained with granulocyres were similar to rhose obtained with monocyres although the elimination of bacteria by monocytes was less than that by granulocytes. These resulcs strongJy suggest that production of ahemolysin is a means by which E. coli counteracrs the activity of phagocytes by injuring these cells with the toxin.}, subject = {Escherichia coli}, language = {en} } @article{KoenigKoenigSchefferetal.1989, author = {K{\"o}nig, W. and K{\"o}nig, B. and Scheffer, J. and Hacker, J{\"o}rg and Goebel, W.}, title = {Role of cloned virulence factors (mannose-resistant hemagglutination, mannose-resistant adhesins) from uropathogenic Escherichia coli strains in release of inflammatory mediators from neutrophils and mast cells}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-59564}, year = {1989}, abstract = {Genetically cloned E. co/i strains expressing cloned virulence factors were studied with regard to their capability to induce inflammatory mediator release from various target cells. Among the strains were E. co/i strains with mannose-resistant haemagglutination (MRH +) and mannose-resistant adhesins, e.g. E. coli 536/21 pANN 80 I /4, E. coli 536/21 pANN 921 and E. coli 536/21 pANN 801-1. In comparison, E. coli 536/21, E. coli 536/21 pGB 30 int and E. coli Kl2, without and with mannosesensitive haemagglutination (MSH±), and adhesins were studied. The properties of the various strains for human PMN with regard to adherence and phagocytosis, chemiluminescence, 5-lipoxygenase activation of arachidonic acid, leukotriene formation, granular enzyme release and release of histamine from rat mast cells were analysed. It is evident that the various 'biochemical processes of cell activation are dissociated events. The highest chemiluminescence response is obtained with strains expressing MSH+, P-M RH+ or S-M RH+; the presence of S-adhesins suppressed the response. Highest leukotriene formation is obtained with E. coli 536/21 pANN 801-4, while E. coli with MSH was inactive. The concomitant presence of haemolysin secretion enhanced mediator release significantly. Our data suggest a potent role for mannose-resistant haemagglutination (MRH), adhesins and haemolysin as virulence factors in inducing the release of inflammatory mediators.}, subject = {Infektionsbiologie}, language = {en} } @article{DandekarRibesTollervey1989, author = {Dandekar, Thomas and Ribes, V. and Tollervey, David}, title = {Schizosaccharomyces pombe U4 small nuclear RNA closely resembles vertebrate U4 and is required for growth}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-29771}, year = {1989}, abstract = {No abstract available}, language = {en} } @article{UlrichsMuellerRuchholtz1989, author = {Ulrichs, Karin and M{\"u}ller-Ruchholtz, W.}, title = {Significant manipulative procedures to reduce immunogenicity of human islet allografts}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45155}, year = {1989}, abstract = {No abstract available}, subject = {Chirurgie}, language = {en} } @article{Krueger1989, author = {Kr{\"u}ger, Hans-Peter}, title = {Speech chronemics - a hidden dimension of speech. Theoretical background, measurement, and clinical validity}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-41037}, year = {1989}, abstract = {Der Begriff "speech chronemics" wird eingef{\"u}hrt, um eine Forschungsrichtung zu charakterisieren, die aus den physikalischen Qualit{\"a}ten des Sprachsignals lediglich das Muster von "an" ("Sprechen") und "aus" ("Pausieren") herauszieht. Die Forschungen zu diesen on-off Mustern lassen sich in die methodischen Dimensionen "zeitliche Einheit", "Zahl der Sprecher" und "Art der prosodischen Maße" gliedern. Es wird gezeigt, daß die Entscheidung eines Untersuchers f{\"u}r eine bestimmte Methodik das Ergebnis seiner Untersuchung nicht unerheblich vorausbestimmt. Es wird dann mit dem Logoport ein neues tragbares Meßinstrument vorgestellt, das es erlaubt, das Sprechverhalten von Probanden bis zu 24 Stunden lang in deren normaler Umgebung aufzuzeichnen. Es werden zwei Experimente beschrieben. Im ersten wird gezeigt, daß die Messung von Artiku1ationspausen valide den psychophysiologischen Aktivierungsstatus abbilden kann. In der zweiten Studie wird die soziotrope Wirksamkeit einer neuen betablockierenden Substanz aufgezeigt: in einer Langzeitstudie verbesserte sich das Interaktionsverhalten von Probanden, die sich sozial schwer tun, im Vergleich zu Plazebo und zum Verhalten von Personen ohne solche Schwierigkeiten. Schließlich wird mit Blick auf neue Studien die Wichtigkeit einer {\"u}berlegten theoretischen Einbettung und einer Standardisierung von situativen und methodischen Merkmalen betont.}, language = {en} } @article{HommersEndres1989, author = {Hommers, Wilfried and Endres, Johann}, title = {Strafe und Schadensersatz im Urteilsverbund}, isbn = {0044-3514}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-43946}, year = {1989}, abstract = {Wenn Strafe und Schadenersatz gemeinsam im Urteil verwendet werden, bilden sie methodisch einen besonderen multi variaten Urteils komplex, weil auch ihre Summe psychologisch interpretierbar ist. Anhand der Effekte dieses Verbunds, den auch das Zivil- und Strafrecht kennt, wurde gepr{\"u}ft, ob der Einsatz eines Doppel-Urteils f{\"u}r die Erforschung sozialer Kognitionen erforderlich ist. Dazu beurteilten Pbn in zwei Untersuchungen Informationen {\"u}ber sch{\"a}digende Handlungen mit einem univariaten Ersatz-Urteil (N = 124) bzw. mit dem Doppel-Urteil von Ersatz und Strafe (N = 143). Als Folge der Einf{\"u}hrung des Doppel-Urteils ergab sich, daß die H{\"a}ufigkeiten von {\"U}ber kompensation f{\"u}r absichtliche Sch{\"a}digungen erheblich reduziert wurden. Jedoch wurden zugleich die H{\"a}ufigkeiten von vollem Ersatz bei diesen Bedingungen betr{\"a}chtlich erh{\"o}ht. Bei versehentlichen Sch{\"a}digungen hatte die Einf{\"u}hrung des Doppel-Urteils keinen Effekt. Weiterhin blieb dort der univariate Befund multipler Modalwerte erhalten. In den Mittelwerten hatte das Mitverschulden des Gesch{\"a}digten nur im Schadensersatz-Urteil einen Effekt, nicht jedoch in den Strafurteilen. Außerdem blieb die f{\"u}r die Schadensersatz- Urteile charakteristische Non-Additivit{\"a}t von Verschulden und Mitschuld bestehen.}, subject = {Sozialpsychologie}, language = {de} } @article{CarrKurtzSchneideretal.1989, author = {Carr, Martha and Kurtz, Beth E. and Schneider, Wolfgang and Turner, Lisa A. and Borkowski, John G.}, title = {Strategy acquisition and transfer among American and German children: Environmental influences on metacognitive development}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-62082}, year = {1989}, abstract = {This study explored the differential effects of strategy training on German and American elementaryschool children and assessed the role of parents in the development of their children's strategic behavior and metacognition. 184 German and 161 American children were pretested on memory and metamemory tasks. Children were then assigned to either an organizational strategy training condition or a control condition. All children were tested on the maintenance and far-transfer of the strategy and task-related metamemory 1 week following training. Parents completed questionnaires about strategy instruction in the home. Strategy maintenance and metacognition were reassessed 6 months following training. German children were more strategic than American children. Instructed children performed better than control children. German parents reported more instruction of strategies in the home. These data suggest that formal education is responsible for aspects of cognitive development that have sometimes been viewed as a function of age.}, subject = {Psychologie}, language = {en} } @article{BernardsSchacklefordGerberetal.1989, author = {Bernards, R. and Schackleford, G. M. and Gerber, M. R. and Horowitz, J. M. and Friend, S. H. and Schartl, Manfred and Bogenmann, E. and Rapaport, J. M. and Mcgee, T. and Dryja, T. P.}, title = {Structure and expression of the murine retinoblastoma gene and characterization of its encoded protein}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-61819}, year = {1989}, abstract = {No abstract available}, subject = {Physiologische Chemie}, language = {en} } @article{FialaMaschwitzPongetal.1989, author = {Fiala, Brigitte and Maschwitz, Ulrich and Pong, Tho, Yow and Helbig, Andreas J.}, title = {Studies of a South East Asian ant-plant association : protection of Macaranga trees by Crematogaster borneensis}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-42857}, year = {1989}, abstract = {In the humid tropics of SE Asia there are some 14 myrmecophytic species of the pioneer tree genus Macaranga (Euphorbiaceae). In Peninsular Malaysia a close association exists between the trees and the small, non-stinging myrmicine Crema togas ter borneensis. These ants feed mainly on food bodies provided by the plants and have their colonies inside the hollow intemodes. In a ten months field study we were able to demonstrate for four Macaranga species (M. triloba, M. hypoleuca, M. hosei, M. hulletti) that host plants also benefit considerably from ant-occupation. Ants do not contribute to the nutrient demands of their host plant, they do, however, protect it against herbivores and plant competition. Cleaning behaviour of the ants results in the removal of potential herbivores already in their earliest developmental stages. Strong aggressiveness and a mass recruiting system enable the ants to defend the host plant against many herbivorous insects. This results in a significant decrease in leaf damage due to herbivores on ant-occupied compared to ant-free myrmecophytes as well as compared to non-myrmecophytic Macaranga species. Most important is the ants' defense of the host plant against plant competitors, especially vines, which are abundant in the well-lit pioneer habitats where Macaranga grows. Ants bite off any foreign plant part coming into contact with their host plant. Both ant-free myrmecophytes and non-myrmecophytic Macaranga species had a significantly higher incidence of vine growth than specimens with active ant colonies. This may be a factor of considerable importance allowing Macaranga plants to grow at sites of strongest competition.}, language = {en} } @article{EngelsPeyerimhoff1989, author = {Engels, Bernd and Peyerimhoff, S.D.}, title = {Study of orbital transformations in configurational interaction calculation of hyperfine coupling in nitrogen and CH molecule}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-58847}, year = {1989}, abstract = {Multi-reference configuration interaction calculations employing various orbital transformations are undertaken to obtain the isotropic hyperfine coupling constant a\(_{iso\) in nitrogen and a\(_{iso\) (H) in the CH molecule. The natural orbital (NO) basis is found to be more effective than the simple RHF-MO basis; the most obvious is a basis of spin natural orbitals (SNO). It is found that a\(_{iso\) is approached from opposite sides in the NO and 2s shell SNO basis if the CI expansion is increased. Both results are within a few percent of the full CI Iimit for the nitrogen atorn (in the given AO basis) and the experimental value for Hin the CH radical. Various features ofthe SNO are discussed.}, subject = {Organische Chemie}, language = {en} } @article{LohseMaurerKlotzetal.1989, author = {Lohse, M. J. and Maurer, K. and Klotz, Karl-Norbert and Schwabe, U.}, title = {Synergistic effects of calcium-mobilizing agents and adenosine on histamine release from rat peritoneal mast cells}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-60346}, year = {1989}, abstract = {1 Adenosine and its metabolically stable analogue N.etbyl-carboxamidoadenosine (NECA) enhance histamine release from rat peritoneal mast cells when tbese are stimulated by calciummobilizing agents. NECA and adenosine shift the concentration-response curve of tbe calcium ionophore A23187 to lower concentrations. 2 The potencies of NECA or adenosinein enhancing A23187-induced histamine release are dependent on the Ievel of stimulated release in tbe absence of adenosine analogues. At high Ievels of release their potencies are up to 20 times higher than at low Ievels. Consequently, averaged concentration-response curves of adenosine and NECA for enhancing bistamine release are shallow. 3 The adenosine transport blocker S-(p-nitrobenzyl)-6-thioinosine (NBTI) has no effect by itself at low Ievels of stimulated histamine release, but abolishes the enhancing effect of adenosine. At high Ievels of release, however, NBTI alone enhances the release of histamine. 4 lt is concluded that adenosine and calcium reciprocally enhance the sensitivity of the secretory processes to the effects of the other agent. The Ievels of intracellular adenosine obtained by trapping adenosine inside stimulated mast cells are sufficient to enhance histamine release substantially, suggesting that this effect may play a physiological and pathophysiological role.}, subject = {Toxikologie}, language = {en} } @article{TackeLinohRafeineretal.1989, author = {Tacke, Reinhold and Linoh, H. and Rafeiner, K. and Lambrecht, G. and Mutschler, E.}, title = {Synthese und Eigenschaften des selektiven Antimuscarinikums Sila-Hexocyclium-methylsulfat}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-63921}, year = {1989}, abstract = {Sila-Hexocyclium-methylsulfat (7b), ein Silicium-Analogon des therapeutisch eingesetzten Antimuscarinileums Hexocyclium-methylsulfat (7a), wurde durch eine sechsstufige Synthese - ausgehend von (CH\(_3\)0)\(_3\)SiCH\(_2\)Cl - dargestellt (Gesamtausbeute 16\%). Außerdem wurden die hiervon abzuleitende freie Base 9b (f{\"u}nfstufige Synthese, ausgehend von (CH\(_3\)0)\(_3\)SiCH\(_2\)O; Gesamtausbeute 29\%) und das strukturverwandte (Aminomethyl)silanol 13 (dreistufige Synthese, ausgehend von cyclo-C\(_6\)H\(_{11}\)(C\(_6\)H\(_5\))Si(OCH\(_3\))CH\(_2\)Cl, Gesamtausbeute 46\$) synthetisiert. 7b ist ein hochwirksames und selektives Antimuscarinikum, das in der experimentellen Pharmakologie aufgrund seines bemerkenswerten Selektivit{\"a}tsprofils zur Klassifizierung von Subtypen muscarinischer Rezeptoren eingesetzt wird.}, subject = {Anorganische Chemie}, language = {de} } @article{TackeRafeinerStrohmannetal.1989, author = {Tacke, Reinhold and Rafeiner, K. and Strohmann, C. and Mutschler, E. and Lambrecht, G.}, title = {Synthesis of the selective antimuscarinic agent 4-{[cyclohexylhydroxy(2-methoxyphenyl)silyl]methyl}-1,1-dimethylpiperazinium methyl sulfate (o-methoxy-sila-hexocyclium methyl sulfate)}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-63930}, year = {1989}, abstract = {The synthesis of the potent and highly selective silicon-containing antimuscarinic agent o-methoxysila- hexocyclium methyl sulfate and its corresponding tertiary amine (isolated as the dihydrochloride) is described. The quarternary compound is an omethoxy derivative of sila-hexocyclium methyl sulfate, which represents one of the tools currently used in experimental pharmacology for the subclassification of muscarinic receptors. The omethoxy derivative, the pharmacological profile of which differs substantially from tbat of the nonmethoxy compound, is also recommended as a tool for the investigation of muscarinic receptor heterogeneity.}, subject = {Anorganische Chemie}, language = {en} } @article{MarreHackerBraun1989, author = {Marre, R. and Hacker, J{\"o}rg and Braun, V.}, title = {The cell-bound hemolysin of Serratia marcescens contributes to uropathogenicity}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-59576}, year = {1989}, abstract = {No abstract available}, subject = {Infektionsbiologie}, language = {en} } @article{BorkowskiSchneiderPressley1989, author = {Borkowski, John G. and Schneider, Wolfgang and Pressley, Michael}, title = {The challenges of teaching good information processing to learning disabled students}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-62117}, year = {1989}, abstract = {A MODEL of good information processing is sketched, describing how metacognitive knowledge influences strategy selection and use. Three factors pose particular problems for learning disabled students as they attempt to acquire metacognitive knowledge and to use study strategies productively: neurological impairments; deficiencies in general world knowledge; and negative beliefs, attitudes, and styles that limit self-efficacy. Creating an educational atmosphere that explicitly builds conceptual (domain-specific) knowledge and teaches positive beliefs about learning potential is essential in promoting metacognitively-oriented instruction.}, subject = {Psychologie}, language = {en} } @article{FeuersteinSirenGoldsteinetal.1989, author = {Feuerstein, G. and Sir{\´e}n, Anna-Leena and Goldstein, DS and Johnson, AK and Zerbe, RL}, title = {The effect of morphine on the hemodynamic and neuroendocrine responses to hemorrhagic shock in conscious rats}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-49033}, year = {1989}, abstract = {We have previously reported that analgesic doses of morphine accelerate mortality of rats exposed to hemorrhage (Feuerstein and Siren: Circ Shock 19:293-300, 1986). To study the potential mechanisms involved in this phenomenon, rats were chronically implanted with catheters in the femoral vessels and morphine (1.5 or 5 mg/kg) was administered 30 min or 24 hr after bleeding (8.5 mll300 g over 5 min) while arterial blood pressure and heart rate were continuously monitored. Furthermore, the effect of morphine (5 mg/kg) on cardiac output (CO) response to hemorrhage was studied in rats chronically equipped with a mini thermistor for CO monitoring by a thermodilution technique. In addition, plasma catecholamines (HPLC), plasma renin activity (PRA, RIA), vasopressin (RIA), pH, and blood gases were also determined. Morphine administration 30 min after hemorrhage produced a pressor response and tachycardia which were in marked contrast to its depressor effect in intact rats. Morphine elevated PRA and epinephrine but not vasopressin, while blood pH and gases showed no consistent change as compared to salinetreated hemorrhaged rats. Morphine given after the bleeding resulted in enhanced cardiac depression in response to a second bleed of 2 m1l300 g. Our data suggest that activation of pressor mechanisms by morphine during hypovolemic hypotension might enhance vasoconstriction in essential organs, depress cardiac function, and further reduce effective tissue perfusion.}, subject = {Medizin}, language = {en} } @book{Wilhelm1989, author = {Wilhelm, Gernot}, title = {The Hurrians / [with a chapter by D. L. Stein]}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-87615}, publisher = {Universit{\"a}t W{\"u}rzburg}, year = {1989}, abstract = {No abstract available.}, subject = {Mesopotamien}, language = {en} } @article{KarnaGreinEngelsetal.1989, author = {Karna, S. and Grein, F. and Engels, Bernd and Peyerimhoff, S.D.}, title = {The hyperfine coupling constants of \(^{19}\)F\(_2\)}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-58817}, year = {1989}, abstract = {The isotropic (a\(_{iso}\)) and dipolar (A\(_{dip}\)) hyperfine coupling constants of 19F2 were obtained from MRD-CI wave functions using a variety of basis sets. In series I, increasing numbers of d functions were added to a 5s4p contracted Huzinaga!Dunning basis. In series II, the 5s3p basis set was uncontracted in several steps until 9s5p was reached, to which were added from one to three d-polarization functions. Cl parameters (selectioo threshoids and the number of reference coofiguratioos) were also varied. A study of the R dependence of aiso and Adip was perfonned. The best values obtained at R\(_e\) are 260 G for a\(_{iso}\) and 308 G for A\(_{dip}\)• compared with experimental values of about 280 G for a;10 and 320 G for A\(_{dip}\)·}, subject = {Organische Chemie}, language = {en} } @article{EngelsPeyerimhoff1989, author = {Engels, Bernd and Peyerimhoff, S.D.}, title = {The hyperfine coupling constants of the X\(^3\)Σ\(^-\) state of NH : Influence of polarization functions and configuration space on the description of spin polarization}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-58832}, year = {1989}, abstract = {The hyperfine coupling constants for the \(^3\)Σ\(-\) ground state of the NH molecule are determined by configuration interaction calculations whereby the infl.uence of polarization functions as weil as of the configuration space on the spin polarization mechanism is analysed. The dipolar part Au(N) and Au(H) can be obtained very reliably without much computational effort (A .. (N) == -45·3 MHz and A"(H) = -62·3 MHz). The value for the isotropic contribution a1.., in the best AO basis and MRD-CI treatment is - 64·5 MHz for H and 16·6 MHz for nitrogen compared to the corresponding experimental quantities of -66 MHz and 19 MHz respectively. Their determination depends on a subtle balance of the lu, 2u and 3u shell correlation description, whereby the dominant contribution to a1..,(H) results from the 2u shell. It is shown that the often good agreement of a110 values with experiment in a small basis singledouble configuration interaction treatment results from a cancellation of two errors.}, subject = {Organische Chemie}, language = {en} } @article{SchneiderKoerkel1989, author = {Schneider, Wolfgang and K{\"o}rkel, Joachim}, title = {The knowledge base and text recall: Evidence from a short-term longitudinal study}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-62093}, year = {1989}, abstract = {In a short-term longitudinal study, we investigated how domain-specific knowledge in soccer influences the amount of text recall and comprehension in elementary school and junior high school children of high and low overall aptitudes. Both level of soccer knowledge and overall aptitude were varied in a factorial design. Third, fifth, and seventh grade children were given several measures of text recall and comprehension and were retested on these measures about 1 year later. Performance was more a function of soccer knowledge than of aptitude level.}, subject = {Psychologie}, language = {en} } @article{FlueggeFischerGrossetal.1989, author = {Fl{\"u}gge, U. I. and Fischer, K. and Gross, A. and Sebald, Walter and Lottspeich, F. and Eckerskorn, C.}, title = {The triose phosphate-3-phosphoglycerate-phosphate translocator from spinach chloroplasts: nucleotide sequence of a full-length cDNA clone and import of the in vitro synthesized precursor protein into chloroplasts}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-62559}, year = {1989}, abstract = {No abstract available}, subject = {Biochemie}, language = {en} } @article{EngelsPeyerimhoff1989, author = {Engels, Bernd and Peyerimhoff, S.D.}, title = {Theoretical study of FC\(_2\)H\(_4\)}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-58824}, year = {1989}, abstract = {Large-scale multireference configuration interaction (MRD-CI) calculations in a quite flexible AO basis are employed to study the energy hypersurface for the reaction intermediate FC\(_2\)H\(_4\) • The reaction F + C\(_2\)H\(_4\) -> FC\(_2\)H\(_4\) as weil as the 1,2 migration of the fluorine atom in FC\(_2\)H\(_4\) is investigated. In addition the rotation around the CC bond in the optimum conformation is studied. The absolute minimum in the potential energy is found for the asymmetric structure but the symmetric structure is also found to be stable with respect to the dissociation, so that a shuttling of the fluorine atom is in principle possible but highly unlikely because ( l) the activation energy is high ( II 5-130 kJ fmol) and the saddle point lies only 4(}-50 kJ jmol below the dissociation Iimit of F + C\(_2\)H\(_4\) and (2) the competitive motion, i.e., rotation around the CC axis, is nearly free (I 1-17 kJ/mol).}, subject = {Organische Chemie}, language = {en} } @article{SirenFeuerstein1989, author = {Sir{\´e}n, Anna-Leena and Feuerstein, G.}, title = {Thyrotropin releasing hormone-induced hindquarter vasodilation is mediated by \(\beta _2\)-adrenoceptors}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-63155}, year = {1989}, abstract = {No abstract available}, subject = {Neurobiologie}, language = {en} } @article{HuenigWehner1989, author = {H{\"u}nig, Siegfried and Wehner, Ingeborg}, title = {Two Step Redox Systems LII: 2,2'-Bipyridylboronium Salts}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-44853}, year = {1989}, abstract = {Dications 1 derived from 2,2-bipyridine are found to exist as fully reversible two step redox systems with persistent radical ions (SEM) of high thermodynamic stability, if the bridge X forces the two pyridine rings into co planar positions. The well known derivative 1a (Diquat R) is now complemented by the boronium ions 1c and 1e -1g., as shown by voltammetry and the uv spectra of the corresponding radicals.}, language = {de} } @inproceedings{SchneiderWeinert1989, author = {Schneider, Wolfgang and Weinert, Franz E.}, title = {Universal trends and individual differences in memory development}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-86518}, year = {1989}, abstract = {No abstract available.}, subject = {Ged{\"a}chtnisbildung}, language = {en} } @incollection{SchulzeTyrellKuenzler1989, author = {Schulze, Hans Joachim and Tyrell, Hartmann and K{\"u}nzler, Jan}, title = {Vom Strukturfunktionalismus zur Systemtheorie der Familie}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-50784}, publisher = {Universit{\"a}t W{\"u}rzburg}, year = {1989}, abstract = {No abstract available}, subject = {Interdisziplin{\"a}re Forschung}, language = {de} } @article{HarthPeter1989, author = {Harth-Peter, Waltraud}, title = {Vorwort (Das Kind (1989) 5)}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-42789}, year = {1989}, abstract = {No abstract available}, subject = {Kind}, language = {de} } @article{HarthPeter1989, author = {Harth-Peter, Waltraud}, title = {Vorwort (Das Kind (1989) 6)}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-42779}, year = {1989}, abstract = {No abstract available}, subject = {Kind}, language = {de} } @incollection{HarthPeterFuchs1989, author = {Harth-Peter, Waltraud and Fuchs, Birgitta}, title = {Vorwort (Montessori-P{\"a}dagogik und die Erziehungsprobleme der Gegenwart)}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-43099}, publisher = {Universit{\"a}t W{\"u}rzburg}, year = {1989}, abstract = {No abstract available}, language = {de} } @article{HarthPeter1989, author = {Harth-Peter, Waltraud}, title = {Was ist mit dem "Freien Ausdruck"? / Maria Montessori ({\"U}bersetzung)}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-51048}, year = {1989}, abstract = {No abstract available}, subject = {Kind}, language = {de} } @misc{HarthPeter1989, author = {Harth-Peter, Waltraud}, title = {Welcher Altersunterschied soll zwischen den Kindern in einer Montessori-Gruppe bestehen? / Rosy Joosten-Cotzen}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-42766}, year = {1989}, abstract = {Im englischen Original: "But, the better may never be the opponent of the best!" Rosy Joosten-Cotzen. Aus dem Englischen {\"u}bersetzt und mit einer Einleitung versehen von Waltraud Harth-Peter: Welcher Altersunterschied soll zwischen den Kindern in einer Montessori-Gruppe bestehen?}, subject = {Erziehung}, language = {de} } @misc{Kuenzler1989, author = {K{\"u}nzler, Jan}, title = {Zur Armutssituation {\"a}lterer Frauen}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-50744}, year = {1989}, abstract = {No abstract available}, subject = {Sozialarbeit}, language = {de} } @book{Schneider1989, author = {Schneider, Wolfgang}, title = {Zur Entwicklung des Meta-Ged{\"a}chtnisses bei Kindern}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-87165}, publisher = {Universit{\"a}t W{\"u}rzburg}, year = {1989}, abstract = {No abstract available.}, subject = {Kind}, language = {de} } @article{Hommers1989, author = {Hommers, Wilfried}, title = {Zur Validierung von Konfigurationstypen generalisierter Kontroll{\"u}berzeugungen}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-69686}, year = {1989}, abstract = {Die Ergebnisse einer publizierten Arbeit zur Validierung von acht Konfigurationen generalisierter Kontroll{\"u}berzeugungen werden durch drei weitere Auswertungsschritte erg{\"a}nzt. Die Anwendung der Interaktionsstrukturanalyse f{\"u}hrt zu einer Hervorhebung von zwei Konfigurationen als Typen und zur Aufstellung einer 5-Gruppen-Hypothese {\"u}ber die Bildung einer Restgruppe aus den Neutral-Konfigurationen. Die Betrachtung der Unterschiede in den FPI-Mittelwerten der urspr{\"u}nglichen acht Gruppen best{\"a}tigt die 5-Gruppen-Hypothese. Mit einer multidimensionalen geometrischen Darstellung der Profildistanzen wird in einem dritten Schritt versucht, neben der "Restgruppe" und den beiden "Typen"-Gruppen auch die Eigenst{\"a}ndigkeit der beiden verbleibenden "Anti-Typen"-Gruppen zu validieren.}, subject = {Validierung}, language = {de} } @article{HommersEndres1989, author = {Hommers, Wilfried and Endres, Johann}, title = {Zur Wirkung der Entschuldigung auf verbundene Urteile von Strafe und Schadensersatz}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-44118}, year = {1989}, abstract = {Mit einem besonderen multivariaten Urteilsverbund von Ersatz und Strafe als abh{\"a}ngige Variable wurden die Wirkungen von Entschuldigung und Verschulden untersucht. 62 erwachsene Pbn beurteilten in zehn Geschichten {\"u}ber eine Briefmarkenruinierung die angemessene Strafe f{\"u}r den Sch{\"a}diger und verbunden damit dessen angemessene Ersatzleistung an den Gesch{\"a}digten und anschließend in vierzehn Geschichten {\"u}ber eine K{\"o}rperverletzung beim Fußballspielen zus{\"a}tzlich zu Strafe und Ersatz auch das angemessene Schmerzensgeld. In bei den Szenarien ergab sich, daß die Entschuldigung auf das Ersatz-Urteil zwar weniger stark als auf die Strafe wirkte, daß sie aber einen deutlichen Effekt auf das Ersatz-Urteil besaß. Weiterhin wurden die Verschuldensstufen auf beiden Skalen mit anderen relativen Distanzen beurteilt. Die Schmerzensgeld-Urteile im Fußball- Szenario {\"a}hnelten weitgehend den Strafe-Urteilen. Auch die Verteilungsformen der Urteile belegten die unterschiedlichen Verwendungsweisen der Teile des Urteilsverbunds. Die untersuchten Urteile scheinen daher zugleich restitutive und punitive Strukturen aufzuweisen, zu deren quantitativer Erfassung Forschungsans{\"a}tze n{\"o}tig sind, die den hier eingef{\"u}hrten Duplex-Verbund von Strafe und Ersatz beinhalten.}, subject = {Angewandte Psychologie / Zeitschrift / Experimentelle Psychologie}, language = {de} }