@article{PauliGlotzbachSchoonAndreattaetal.2013,
  author    = {Pauli, Paul and Glotzbach-Schoon, Evelyn and Andreatta, Marta and Reif, Andreas and Ewald, Heike and Tr{\"o}ger, Christian and Baumann, Christian and Deckert, J{\"u}rgen and M{\"u}hlberger, Andreas},
  title     = {Contextual fear conditioning in virtual reality is affected by 5HTTLPR and NPSR1 polymorphisms: effects on fear-potentiated startle},
  series = {Frontiers in Behavioral Neuroscience},
  journal   = {Frontiers in Behavioral Neuroscience},
  doi       = {10.3389/fnbeh.2013.00031},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-96516},
  year      = {2013},
  abstract  = {The serotonin (5-HT) and neuropeptide S (NPS) systems are discussed as important genetic modulators of fear and sustained anxiety contributing to the etiology of anxiety disorders. Sustained anxiety is a crucial characteristic of most anxiety disorders which likely develops through contextual fear conditioning. This study investigated if and how genetic alterations of the 5-HT and the NPS systems as well as their interaction modulate contextual fear conditioning; specifically, function polymorphic variants in the genes coding for the 5-HT transporter (5HTT) and the NPS receptor (NPSR1) were studied. A large group of healthy volunteers was therefore stratified for 5HTTLPR (S+ vs. LL carriers) and NPSR1 rs324981 (T+ vs. AA carriers) polymorphisms resulting in four genotype groups (S+/T+, S+/AA, LL/T+, LL/AA) of 20 participants each. All participants underwent contextual fear conditioning and extinction using a virtual reality (VR) paradigm. During acquisition, one virtual office room (anxiety context, CXT+) was paired with an unpredictable electric stimulus (unconditioned stimulus, US), whereas another virtual office room was not paired with any US (safety context, CXT-). During extinction no US was administered. Anxiety responses were quantified by fear-potentiated startle and ratings. Most importantly, we found a gene × gene interaction on fear-potentiated startle. Only carriers of both risk alleles (S+/T+) exhibited higher startle responses in CXT+ compared to CXT-. In contrast, anxiety ratings were only influenced by the NPSR1 polymorphism with AA carriers showing higher anxiety ratings in CXT+ as compared to CXT-. Our results speak in favor of a two level account of fear conditioning with diverging effects on implicit vs. explicit fear responses. Enhanced contextual fear conditioning as reflected in potentiated startle responses may be an endophenotype for anxiety disorders.},
  language  = {en}
}
@article{WeberScholzDomschkeetal.2012,
  author    = {Weber, Heike and Scholz, Claus J{\"u}rgen and Domschke, Katharina and Baumann, Christian and Klauke, Benedikt and Jacob, Christian P. and Maier, Wolfgang and Fritze, J{\"u}rgen and Bandelow, Borwin and Zwanzger, Peter Michael and Lang, Thomas and Fehm, Lydia and Str{\"o}hle, Andreas and Hamm, Alfons and Gerlach, Alexander L. and Alpers, Georg W. and Kircher, Tilo and Wittchen, Hans-Ulrich and Arolt, Volker and Pauli, Paul and Deckert, J{\"u}rgen and Reif, Andreas},
  title     = {Gender Differences in Associations of Glutamate Decarboxylase 1 Gene (GAD1) Variants with Panic Disorder},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-75830},
  year      = {2012},
  abstract  = {Background: Panic disorder is common (5\% prevalence) and females are twice as likely to be affected as males. The heritable component of panic disorder is estimated at 48\%. Glutamic acid dehydrogenase GAD1, the key enzyme for the synthesis of the inhibitory and anxiolytic neurotransmitter GABA, is supposed to influence various mental disorders, including mood and anxiety disorders. In a recent association study in depression, which is highly comorbid with panic disorder, GAD1 risk allele associations were restricted to females. Methodology/Principal Findings: Nineteen single nucleotide polymorphisms (SNPs) tagging the common variation in GAD1 were genotyped in two independent gender and age matched case-control samples (discovery sample n = 478; replication sample n = 584). Thirteen SNPs passed quality control and were examined for gender-specific enrichment of risk alleles associated with panic disorder by using logistic regression including a genotype6gender interaction term. The latter was found to be nominally significant for four SNPs (rs1978340, rs3762555, rs3749034, rs2241165) in the discovery sample; of note, the respective minor/risk alleles were associated with panic disorder only in females. These findings were not confirmed in the replication sample; however, the genotype6gender interaction of rs3749034 remained significant in the combined sample. Furthermore, this polymorphism showed a nominally significant association with the Agoraphobic Cognitions Questionnaire sum score. Conclusions/Significance: The present study represents the first systematic evaluation of gender-specific enrichment of risk alleles of the common SNP variation in the panic disorder candidate gene GAD1. Our tentative results provide a possible explanation for the higher susceptibility of females to panic disorder.},
  subject      = {Medizin},
  language  = {en}
}
@unpublished{BaumannWillaschekKertessSzlaninkaetal.2017,
  author    = {Baumann, Christoph and Willaschek, Christian and Kertess-Szlaninka, Tuende and Lang, Johanna and Buchhorn, Reiner},
  title     = {Implementing high energy liquid nutrition, omega-3 fatty acids and nutritional supplements for the treatment of anorexia nervosa},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-150430},
  year      = {2017},
  abstract  = {Objective: To examine the effects of two different treatment approaches on the course of anorexia nervosa (AN) over time. Methods: The subjects were 27 hospitalized AN patients (mean age: 14.91 years; mean BMI: 14.58; mean height: 163.56) . In our retrospective analysis we compared weight gain in two groups. While one group was treated with a standard oral refeeding protocol (historical control) through January 2013 (N=16), the second group (highly standardized refeeding protocol) received a high energy liquid nutrition and nutritional supplements including omega-3 fatty acids (N=11). Results: On admission, the two groups were comparable in terms of height, weight, age and heart rate. At the end of our monitoring time frame of 25 days, weight gain was 121.4\% higher in the highly standardized refeeding protocol group than in the historical control group (66.5 ±52.4 vs 147.3 ±55.7 grams/day; t-Test p=0.004; CI95\%: 29.3-132.2). About 45\% of our patients stated they were vegetarians at admission. However, we could not identify a vegetarian diet as a statistically significant negative prognostic factor for weight gain. Discussion: The highly standardized refeeding protocol seems to be helpful in malnourished AN patients to improve weight gain without enhancing the risk of a refeeding syndrome. Because of an increasing energy turnover, caloric intake should be adjusted during refeeding.},
  subject      = {Anorexia nervosa},
  language  = {en}
}
@article{WieberBaumannBurschka1977,
  author    = {Wieber, Markus and Baumann, Norbert and Burschka, Christian},
  title     = {Kristall- und Molek{\"u}lstruktur eines koordinationspolymeren 2-Organo-1.3.2-dioxastibols},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-46796},
  year      = {1977},
  abstract  = {No abstract available},
  subject      = {Chemie},
  language  = {de}
}
@article{BaumannBurschkaSchenk1986,
  author    = {Baumann, Franz Erich and Burschka, Christian and Schenk, Wolfdieter A.},
  title     = {Ligandensubstitution an cis-Mo(CO)\(_2\)(PPh\(_3\)h(MeCN)(\(\eta^2\)-S0\(_2\)), Kristall- und Molek{\"u}lstruktur von cis-Mo(CO)\(_2\)(PMe\(_3\))\(_3\)(\(\eta^2\)-S0\(_2\)) [1]},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-47143},
  year      = {1986},
  abstract  = {No abstract available},
  subject      = {Chemie},
  language  = {de}
}
@article{HornBaumannPereiraetal.2012,
  author    = {Horn, Michael and Baumann, Reto and Pereira, Jorge A. and Sidiropoulos, P{\´a}ris N. M. and Somandin, Christian and Welzl, Hans and Stendel, Claudia and L{\"u}hmann, Tessa and Wessig, Carsten and Toyka, Klaus V. and Relvas, Jo{\~a}o B. and Senderek, Jan and Suter, Ueli},
  title     = {Myelin is dependent on the Charcot-Marie-Tooth Type 4H disease culprit protein FRABIN/FGD4 in Schwann cells},
  series = {Brain},
  volume    = {135},
  journal   = {Brain},
  doi       = {10.1093/brain/aws275},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-125390},
  pages     = {3567-3583},
  year      = {2012},
  abstract  = {Studying the function and malfunction of genes and proteins associated with inherited forms of peripheral neuropathies has provided multiple clues to our understanding of myelinated nerves in health and disease. Here, we have generated a mouse model for the peripheral neuropathy Charcot-Marie-Tooth disease type 4H by constitutively disrupting the mouse orthologue of the suspected culprit gene FGD4 that encodes the small RhoGTPase Cdc42-guanine nucleotide exchange factor Frabin. Lack of Frabin/Fgd4 causes dysmyelination in mice in early peripheral nerve development, followed by profound myelin abnormalities and demyelination at later stages. At the age of 60 weeks, this was accompanied by electrophysiological deficits. By crossing mice carrying alleles of Frabin/Fgd4 flanked by loxP sequences with animals expressing Cre recombinase in a cell type-specific manner, we show that Schwann cell-autonomous Frabin/Fgd4 function is essential for proper myelination without detectable primary contributions from neurons. Deletion of Frabin/Fgd4 in Schwann cells of fully myelinated nerve fibres revealed that this protein is not only required for correct nerve development but also for accurate myelin maintenance. Moreover, we established that correct activation of Cdc42 is dependent on Frabin/Fgd4 function in healthy peripheral nerves. Genetic disruption of Cdc42 in Schwann cells of adult myelinated nerves resulted in myelin alterations similar to those observed in Frabin/Fgd4-deficient mice, indicating that Cdc42 and the Frabin/Fgd4-Cdc42 axis are critical for myelin homeostasis. In line with known regulatory roles of Cdc42, we found that Frabin/Fgd4 regulates Schwann cell endocytosis, a process that is increasingly recognized as a relevant mechanism in peripheral nerve pathophysiology. Taken together, our results indicate that regulation of Cdc42 by Frabin/Fgd4 in Schwann cells is critical for the structure and function of the peripheral nervous system. In particular, this regulatory link is continuously required in adult fully myelinated nerve fibres. Thus, mechanisms regulated by Frabin/Fgd4-Cdc42 are promising targets that can help to identify additional regulators of myelin development and homeostasis, which may crucially contribute also to malfunctions in different types of peripheral neuropathies.},
  language  = {en}
}
@article{BurschkaBaumannSchenk1983,
  author    = {Burschka, Christian and Baumann, F.-E. and Schenk, W. A.},
  title     = {Schwefel(IV)-Verbindungen als Liganden. II. Die Kristall- und Molek{\"u}lstruktur von Pentacarbonyl-(schwefeldioxid)chrom},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-31388},
  year      = {1983},
  abstract  = {Die Struktur von Pentacarbonyl(schwefeldioxid)chrom (1) wurde r{\"o}ntgenographisch aus Einkristalldaten bestimmt. Die Verbindung kristallisiert mit acht Formeleinheiten in der rhombischen Elementarzelle (Raumgruppe Pbn2\(_1\)) folgender Dimensionen: a = 657,8(2) pm, b = 1245,2(4) pm, c = 2177,4(5) pm (bei 180 K). Das Schwefeldioxid ist \(\eta^1\)-koplanar koordiniert, der Cr-S-Abstand ist mit 219 pm der k{\"u}rzeste bisher gefundene Abstand zwischen Chrom(O) und Schwefel. Die Cr-C(ax)-Bindung ist mit 189 pm fast genau so lang wie die Cr-C(eq).Bindungen (190 pm), ein Beleg f{\"u}r das hohe \(\pi\)-Akzeptorverm{\"o}gen des S0\(_2\).},
  subject      = {Chemie},
  language  = {de}
}
@article{HarterHaukeHeitzetal.2017,
  author    = {Harter, Philipp and Hauke, Jan and Heitz, Florian and Reuss, Alexander and Kommoss, Stefan and Marm{\´e}, Frederik and Heimbach, Andr{\´e} and Prieske, Katharina and Richters, Lisa and Burges, Alexander and Neidhardt, Guido and de Gregorio, Nikolaus and El-Balat, Ahmed and Hilpert, Felix and Meier, Werner and Kimmig, Rainer and Kast, Karin and Sehouli, Jalid and Baumann, Klaus and Jackisch, Christian and Park-Simon, Tjoung-Won and Hanker, Lars and Kr{\"o}ber, Sandra and Pfisterer, Jacobus and Gevensleben, Heidrun and Schnelzer, Andreas and Dietrich, Dimo and Neunh{\"o}ffer, Tanja and Krockenberger, Mathias and Brucker, Sara Y. and N{\"u}rnberg, Peter and Thiele, Holger and Altm{\"u}ller, Janine and Lamla, Josefin and Elser, Gabriele and du Bois, Andreas and Hahnen, Eric and Schmutzler, Rita},
  title     = {Prevalence of deleterious germline variants in risk genes including \(BRCA1/2\) in consecutive ovarian cancer patients (AGO-TR-1)},
  series = {PLoS ONE},
  volume    = {12},
  journal   = {PLoS ONE},
  number    = {10},
  doi       = {10.1371/journal.pone.0186043},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-173553},
  year      = {2017},
  abstract  = {Background Identification of families at risk for ovarian cancer offers the opportunity to consider prophylactic surgery thus reducing ovarian cancer mortality. So far, identification of potentially affected families in Germany was solely performed via family history and numbers of affected family members with breast or ovarian cancer. However, neither the prevalence of deleterious variants in \(BRCA1/2\) in ovarian cancer in Germany nor the reliability of family history as trigger for genetic counselling has ever been evaluated. Methods Prospective counseling and germline testing of consecutive patients with primary diagnosis or with platinum-sensitive relapse of an invasive epithelial ovarian cancer. Testing included 25 candidate and established risk genes. Among these 25 genes, 16 genes (\(ATM\), \(BRCA1\), \(BRCA2\), \(CDH1\), \(CHEK2\), \(MLH1\), \(MSH2\), \(MSH6\), \(NBN\), \(PMS2\), \(PTEN\), \(PALB2\), \(RAD51C\), \(RAD51D\), \(STK11\), \(TP53\)) were defined as established cancer risk genes. A positive family history was defined as at least one relative with breast cancer or ovarian cancer or breast cancer in personal history. Results In total, we analyzed 523 patients: 281 patients with primary diagnosis of ovarian cancer and 242 patients with relapsed disease. Median age at primary diagnosis was 58 years (range 16-93) and 406 patients (77.6\%) had a high-grade serous ovarian cancer. In total, 27.9\% of the patients showed at least one deleterious variant in all 25 investigated genes and 26.4\% in the defined 16 risk genes. Deleterious variants were most prevalent in the \(BRCA1\) (15.5\%), \(BRCA2\) (5.5\%), \(RAD51C\) (2.5\%) and \(PALB2\) (1.1\%) genes. The prevalence of deleterious variants did not differ significantly between patients at primary diagnosis and relapse. The prevalence of deleterious variants in \(BRCA1/2\) (and in all 16 risk genes) in patients <60 years was 30.2\% (33.2\%) versus 10.6\% (18.9\%) in patients \(\geq\)60 years. Family history was positive in 43\% of all patients. Patients with a positive family history had a prevalence of deleterious variants of 31.6\% (36.0\%) versus 11.4\% (17.6\%) and histologic subtype of high grade serous ovarian cancer versus other showed a prevalence of deleterious variants of 23.2\% (29.1\%) and 10.2\% (14.8\%), respectively. Testing only for \(BRCA1/2\) would miss in our series more than 5\% of the patients with a deleterious variant in established risk genes. Conclusions 26.4\% of all patients harbor at least one deleterious variant in established risk genes. The threshold of 10\% mutation rate which is accepted for reimbursement by health care providers in Germany was observed in all subgroups analyzed and neither age at primary diagnosis nor histo-type or family history sufficiently enough could identify a subgroup not eligible for genetic counselling and testing. Genetic testing should therefore be offered to every patient with invasive epithelial ovarian cancer and limiting testing to \(BRCA1/2\) seems to be not sufficient.},
  language  = {en}
}
@article{HeIffLundtetal.2016,
  author    = {He, Yu-Ming and Iff, Oliver and Lundt, Nils and Baumann, Vasilij and Davanco, Marcelo and Srinivasan, Kartik and H{\"o}fling, Sven and Schneider, Christian},
  title     = {Cascaded emission of single photons from the biexciton in monolayered WSe\(_{2}\)},
  series = {Nature Communications},
  volume    = {7},
  journal   = {Nature Communications},
  doi       = {10.1038/ncomms13409},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-169363},
  year      = {2016},
  abstract  = {Monolayers of transition metal dichalcogenide materials emerged as a new material class to study excitonic effects in solid state, as they benefit from enormous Coulomb correlations between electrons and holes. Especially in WSe\(_{2}\), sharp emission features have been observed at cryogenic temperatures, which act as single photon sources. Tight exciton localization has been assumed to induce an anharmonic excitation spectrum; however, the evidence of the hypothesis, namely the demonstration of a localized biexciton, is elusive. Here we unambiguously demonstrate the existence of a localized biexciton in a monolayer of WSe\(_{2}\), which triggers an emission cascade of single photons. The biexciton is identified by its time-resolved photoluminescence, superlinearity and distinct polarization in micro-photoluminescence experiments. We evidence the cascaded nature of the emission process in a cross-correlation experiment, which yields a strong bunching behaviour. Our work paves the way to a new generation of quantum optics experiments with two-dimensional semiconductors.},
  language  = {en}
}
@phdthesis{Baumann2018,
  author    = {Baumann, Christian},
  title     = {Psychologische und genetische Einflussfaktoren auf die Furchtkonditionierung und die Generalisierung konditionierter Furcht},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-153656},
  school      = {Universit{\"a}t W{\"u}rzburg},
  year      = {2018},
  abstract  = {Bei der Entstehung und Aufrechterhaltung von Furcht und Angsterkrankungen stellt, neben der Furchtkonditionierung, die Generalisierung der konditionierten Furcht einen wesentlichen Mechanismus dar. Die der Generalisierung zugrunde liegenden psychologischen und biologischen Prozesse sind jedoch beim Menschen bisher nur wenig untersucht. Ziel dieser Arbeit war, anhand eines neu entwickelten experimentellen Paradigmas den Einfluss eines psychometrisch bestimmbaren angstspezifischen Faktors sowie der mit Furcht und Angst assoziierten Genotypen Stathmin1, COMT Val158Met und BDNF Val66Met auf die Furchtkonditionierung und Generalisierung konditionierter Furcht zu untersuchen und somit m{\"o}gliche Risikofaktoren f{\"u}r die Entstehung von Angsterkrankungen zu bestimmen. Hierf{\"u}r wurden N = 126 gesunde Versuchspersonen (n = 69 weiblich; mittleres Alter M = 23.05, SD = 3.82) f{\"u}r die genannten Polymorphismen genotypisiert und zu {\"a}ngstlichen und affektiven Symptomen befragt. In einer Akquisitionsphase wurden den Probanden zwei neutrale weibliche Gesichter pr{\"a}sentiert (CS), von denen eines mit einem Schrei sowie einem {\"a}ngstlichen Gesichtsausdruck (UCS) gepaart wurde. Der sich anschließende Generalisierungstest erfolgte anhand von vier Gesichtern, die in der {\"A}hnlichkeit zwischen den beiden CS schrittweise {\"u}bergingen. Die Furchtreaktion wurde {\"u}ber die Bewertung von Valenz, Arousal und Kontingenzerwartung sowie {\"u}ber die Hautleitf{\"a}higkeitsreaktion (SCR) erfasst. Die Analyse der Frageb{\"o}gen anhand einer Hauptachsenanalyse und anhand von Strukturgleichungsmodellen erbrachte eine zweifaktorielle L{\"o}sung, die die Konstrukte Depression und Angst abbildete. Nur der Faktor Angst war mit einer ver{\"a}nderten Furchtkonditionierung und Furchtgeneralisierung assoziiert: Hoch {\"A}ngstliche zeigten eine st{\"a}rkere konditionierte Furchtreaktion (Arousal) und wiesen eine st{\"a}rkere Generalisierung der Valenzeinsch{\"a}tzung und Kontingenzerwartung auf. F{\"u}r den Stathmin1 Genotyp ergaben sich geschlechtsspezifische Effekte. Bei den m{\"a}nnlichen Versuchspersonen zeigte sich in Folge der Akquisition ein st{\"a}rkerer Abfall der Valenz f{\"u}r den CS+ in der Gruppe der Stathmin1 T Alleltr{\"a}ger, die ebenfalls eine st{\"a}rkere Generalisierung der Furchtreaktion, abgebildet in allen verbalen Maßen, aufwiesen. Ein gegenteiliger Befund ergab sich f{\"u}r die Gruppe der Frauen, insofern eine mit dem Stathmin1 C Allel assoziierte h{\"o}here Generalisierung der Valenz, des Arousals und der Kontingenzerwartung festgestellt werden konnte. F{\"u}r den COMT Val158Met Genotyp ergaben sich keine Einfl{\"u}sse auf die Akquisition der konditionierten Furcht. F{\"u}r Tr{\"a}ger des COMT 158Val Allels zeigte sich jedoch eine st{\"a}rkere Generalisierung der Valenz und der Kontingenzerwartung. Auch f{\"u}r den BDNF Val66Met Genotyp konnte keine Ver{\"a}nderung der Furchtakquisition beobachtet werden. Es ergaben sich jedoch Hinweise auf eine erh{\"o}hte Generalisierung der Kontingenzerwartung in der Gruppe der BDNF 66Val Homozygoten. F{\"u}r keinen der beschriebenen Faktoren konnte ein Einfluss auf die Furchtkonditionierung oder deren Generalisierung anhand der SCR abgebildet werden. Unsere Ergebnisse weisen auf einen psychometrisch erfassbaren Faktor und genetische Einfl{\"u}sse hin, die {\"u}ber den Prozess einer st{\"a}rkeren Generalisierung der konditionierten Furcht das Risiko f{\"u}r die Entstehung von Angsterkrankungen erh{\"o}hen k{\"o}nnen. Jedoch sollten die Befunde in gr{\"o}ßeren Stichproben repliziert werden. Neben der fr{\"u}hzeitigen Identifikation von Risikofaktoren sollten in zuk{\"u}nftigen Studien dar{\"u}ber hinaus wirksame Maßnahmen zur Pr{\"a}vention und Intervention entwickelt werden, um diesem Risiko entgegen zu wirken.},
  subject      = {Konditionierung},
  language  = {de}
}
@article{BuchhornBaumannWillaschek2021,
  author    = {Buchhorn, Reiner and Baumann, Christoph and Willaschek, Christian},
  title     = {Pathophysiological mechanisms of bradycardia in patients with anorexia nervosa},
  series = {Health Science Reports},
  volume    = {4},
  journal   = {Health Science Reports},
  number    = {3},
  doi       = {10.1002/hsr2.331},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-244724},
  year      = {2021},
  abstract  = {Background The purpose of this investigation was to examine heart rate variability (HRV), interbeat interval (IBI), and their interrelationship in healthy controls, bradycardic hyperpolarization-activated cyclic nucleotide-gated channel 4 (HCN4) mutation carriers, and patients with anorexia nervosa (AN). We tested the hypothesis that neural mechanisms cause bradycardia in patients with AN. Therefore, we assumed that saturation of the HRV/IBI relationship as a consequence of sustained parasympathetic control of the sinus node is exclusively detectable in patients with AN. Methods Patients with AN between the ages of 12 and 16 years admitted to our hospital due to malnutrition were grouped and included in the present investigation (N = 20). A matched-pair group with healthy children and adolescents was created. Groups were matched for age and sex. A 24-hour Holter electrocardiography (ECG) was performed in controls and patients. More specifically, all patients underwent two 24-hour Holter ECG examinations (admission; refeeding treatment). Additionally, the IBI was recorded during the night in HCN4 mutation carriers (N = 4). HRV parameters were analyzed in 5-minute sequences during the night and plotted against mean corresponding IBI length. HRV, IBI, and their interrelationship were examined using Spearman's rank correlation analyses, Mann-Whitney U tests, and Wilcoxon signed-rank tests. Results The relationship between IBI and HRV showed signs of saturation in patients with AN. Furthermore, signs of HRV saturation were present in two HCN4 mutation carriers. In contrast, signs of HRV saturation were not present in controls. Conclusions The existence of HRV saturation does not support the existence of parasympathetically mediated bradycardia. Nonneural mechanisms, such as HCN4 downregulation, may be responsible for bradycardia and HRV saturation in patients with AN.},
  language  = {en}
}
@article{WurdackLundtKlaasetal.2017,
  author    = {Wurdack, Matthias and Lundt, Nils and Klaas, Martin and Baumann, Vasilij and Kavokin, Alexey V. and H{\"o}fling, Sven and Schneider, Christian},
  title     = {Observation of hybrid Tamm-plasmon exciton-polaritons with GaAs quantum wells and a MoSe\(_{2}\) monolayer},
  series = {Nature Communications},
  volume    = {8},
  journal   = {Nature Communications},
  number    = {259},
  doi       = {10.1038/s41467-017-00155-w},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-170480},
  year      = {2017},
  abstract  = {Strong light matter coupling between excitons and microcavity photons, as described in the framework of cavity quantum electrodynamics, leads to the hybridization of light and matter excitations. The regime of collective strong coupling arises, when various excitations from different host media are strongly coupled to the same optical resonance. This leads to a well-controllable admixture of various matter components in three hybrid polariton modes. Here, we study a cavity device with four embedded GaAs quantum wells hosting excitons that are spectrally matched to the A-valley exciton resonance of a MoSe\(_{2}\) monolayer. The formation of hybrid polariton modes is evidenced in momentum resolved photoluminescence and reflectivity studies. We describe the energy and k-vector distribution of exciton-polaritons along the hybrid modes by a thermodynamic model, which yields a very good agreement with the experiment.},
  language  = {en}
}