@article{HellerKrueger1978, author = {Heller, Dieter and Kr{\"u}ger, Hans-Peter}, title = {Die Sinnentnahme aus Texten in Abh{\"a}ngigkeit von der Schriftart}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-41004}, year = {1978}, abstract = {Texte in drei Schriftarten (Normalschrift, Großschrift und Kleinschrift) wurden 215 Kindern der 5. Jahrgangsstufe vorgelegt mit dem Ziel, die Leistung bei der Sinnentnahme zu vergleichen. Gleichzeitig wurden von den Vpn Urteile {\"u}ber die Erm{\"u}dung, die Anstrengung und die Schriftschwere abgegeben. Die schlechteste Sinnentnahme-Leistung trat auf bei Texten, die nur aus Großbuchstaben bestanden. Die Urteile der Vpn deckten sich mit den Leistungen bei der Sinnentnahme. Eine Aufteilung der Vpn nach Leistungsgruppen zeigte, daß gute Leser auf die Variation der Schrift in der Leistung wie in den Urteilen ausgepr{\"a}gter reagierten.}, language = {de} } @article{HellerKrueger1976, author = {Heller, Dieter and Kr{\"u}ger, Hans-Peter}, title = {Analyse dreistufig zu beantwortender Fragebogenitems}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-41583}, year = {1976}, abstract = {In Frageb{\"o}gen tauchen h{\"a}ufig tern{\"a}re Antwortm{\"o}glichkeiten auf (z.B. ja - nein - weiß nicht). F{\"u}r eine Analyse solcher Hems werden Kennwerte vorgeschlagen. Dabei wird ein der Schwierigkeit analoger Popularit{\"a}tsindex eingef{\"u}hrt, der in p+ den Anteil der Ja-Antworten angibt. Aus p+ und p-, dem Anteil der Nein-Antworten, wird ein Aktualit{\"a}tsindex definiert, der in den Grenzen zwischen 0 und 1 variiert und die Eliminierung wenig aktueller Fragen gestattet. Zur Bestimmung der Trennsch{\"a}rfe werden Punkt-Vierfelder- oder phi-Koeffizienten angegeben. die aus der Zerlegung des X2 einer 3x2-Tafel in eine 2x2-Tafel und in eine auf die Unbestimmtheitsantwort zur{\"u}ckgehende Restkomponente entstehen. Ebenso werden Koeffizienten f{\"u}r Iteminterkorrelationen aus 3x3-Tafeln und Indizes f{\"u}r die Reliabilit{\"a}t angegeben.}, language = {de} } @inproceedings{KruegerHeller1989, author = {Kr{\"u}ger, Hans-Peter and Heller, Dieter}, title = {Psychomotorische Effekte von Alkohol}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-87079}, year = {1989}, abstract = {No abstract available.}, subject = {Psychomotorik}, language = {de} } @article{DumontWeberLassalleJolyBeauparlantetal.2022, author = {Dumont, Martine and Weber-Lassalle, Nana and Joly-Beauparlant, Charles and Ernst, Corinna and Droit, Arnaud and Feng, Bing-Jian and Dubois, St{\´e}phane and Collin-Deschesnes, Annie-Claude and Soucy, Penny and Vall{\´e}e, Maxime and Fournier, Fr{\´e}d{\´e}ric and Lema{\c{c}}on, Audrey and Adank, Muriel A. and Allen, Jamie and Altm{\"u}ller, Janine and Arnold, Norbert and Ausems, Margreet G. E. M. and Berutti, Riccardo and Bolla, Manjeet K. and Bull, Shelley and Carvalho, Sara and Cornelissen, Sten and Dufault, Michael R. and Dunning, Alison M. and Engel, Christoph and Gehrig, Andrea and Geurts-Giele, Willemina R. R. and Gieger, Christian and Green, Jessica and Hackmann, Karl and Helmy, Mohamed and Hentschel, Julia and Hogervorst, Frans B. L. and Hollestelle, Antoinette and Hooning, Maartje J. and Horv{\´a}th, Judit and Ikram, M. Arfan and Kaulfuß, Silke and Keeman, Renske and Kuang, Da and Luccarini, Craig and Maier, Wolfgang and Martens, John W. M. and Niederacher, Dieter and N{\"u}rnberg, Peter and Ott, Claus-Eric and Peters, Annette and Pharoah, Paul D. P. and Ramirez, Alfredo and Ramser, Juliane and Riedel-Heller, Steffi and Schmidt, Gunnar and Shah, Mitul and Scherer, Martin and St{\"a}bler, Antje and Strom, Tim M. and Sutter, Christian and Thiele, Holger and van Asperen, Christi J. and van der Kolk, Lizet and van der Luijt, Rob B. and Volk, Alexander E. and Wagner, Michael and Waisfisz, Quinten and Wang, Qin and Wang-Gohrke, Shan and Weber, Bernhard H. F. and Devilee, Peter and Tavtigian, Sean and Bader, Gary D. and Meindl, Alfons and Goldgar, David E. and Andrulis, Irene L. and Schmutzler, Rita K. and Easton, Douglas F. and Schmidt, Marjanka K. and Hahnen, Eric and Simard, Jacques}, title = {Uncovering the contribution of moderate-penetrance susceptibility genes to breast cancer by whole-exome sequencing and targeted enrichment sequencing of candidate genes in women of European ancestry}, series = {Cancers}, volume = {14}, journal = {Cancers}, number = {14}, issn = {2072-6694}, doi = {10.3390/cancers14143363}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-281768}, year = {2022}, abstract = {Rare variants in at least 10 genes, including BRCA1, BRCA2, PALB2, ATM, and CHEK2, are associated with increased risk of breast cancer; however, these variants, in combination with common variants identified through genome-wide association studies, explain only a fraction of the familial aggregation of the disease. To identify further susceptibility genes, we performed a two-stage whole-exome sequencing study. In the discovery stage, samples from 1528 breast cancer cases enriched for breast cancer susceptibility and 3733 geographically matched unaffected controls were sequenced. Using five different filtering and gene prioritization strategies, 198 genes were selected for further validation. These genes, and a panel of 32 known or suspected breast cancer susceptibility genes, were assessed in a validation set of 6211 cases and 6019 controls for their association with risk of breast cancer overall, and by estrogen receptor (ER) disease subtypes, using gene burden tests applied to loss-of-function and rare missense variants. Twenty genes showed nominal evidence of association (p-value < 0.05) with either overall or subtype-specific breast cancer. Our study had the statistical power to detect susceptibility genes with effect sizes similar to ATM, CHEK2, and PALB2, however, it was underpowered to identify genes in which susceptibility variants are rarer or confer smaller effect sizes. Larger sample sizes would be required in order to identify such genes.}, language = {en} } @article{StratosHellerRudert2022, author = {Stratos, Ioannis and Heller, Karl-Dieter and Rudert, Maximilian}, title = {German surgeons' technical preferences for performing total hip arthroplasties: a survey from the National Endoprosthesis Society}, series = {International Orthopaedics}, volume = {46}, journal = {International Orthopaedics}, number = {4}, doi = {10.1007/s00264-021-05188-x}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-266350}, pages = {733-739}, year = {2022}, abstract = {Purpose The goal of our study was to conduct an online survey that highlights patterns of practice during total hip arthroplasty (THA). Methods The survey was conducted in June and August 2020. Three hundred thirteen members of the German Society for Endoprosthesis participated in the survey. Results The anterolateral approach is by far the most popular approach used for primary total hip arthroplasty, followed by the anterior approach during minimally invasive (55\% for the anterolateral and 29\% for the anterior) and regular surgery (52\% for the anterolateral and 20\% for the anterior). Two-thirds of the orthopaedic surgeons do not use drainages during THA. Moreover, 80\% of the survey participants routinely apply tranexamic acid during surgery. Surgeons who perform minimally invasive surgery for THA use more frequently fast-track-concepts for post-operative rehabilitation. According to the interviewees, the application of fast-track-concepts leads to reduced periods of hospital stay after THA. Conclusion Our data demonstrate that patterns of practice during THA in Germany are in line with the evidence provided by current literature. This study can be seen as a stimulus to conduct similar surveys in other countries in order to promote minimally invasive surgery for THA.}, language = {en} }