@inproceedings{HeiserUlrichsEcksteinetal.1992, author = {Heiser, A. and Ulrichs, Karin and Eckstein, V. and M{\"u}ller-Ruchholtz, W.}, title = {The Human Cell Mediated Response to Xenogeneic (Porcine) Transplantation Antigen Depends on the Stimulator Cell Compartment}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45670}, year = {1992}, abstract = {No abstract available}, language = {en} } @inproceedings{HedkeEcksteinMayetal.1993, author = {Hedke, K. and Eckstein, V. and May, G. and Kaden, J. and M{\"u}ller-Ruchholtz, W. and Ulrichs, Karin}, title = {Production of Xenophile Antibodies (XA) in Type I Diabetic Patients is Strongly Influenced by Diabetes and/or Dialysis}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45642}, year = {1993}, abstract = {No abstract available}, language = {en} } @inproceedings{UlrichsEcksteinKorsgrenetal.1993, author = {Ulrichs, Karin and Eckstein, V. and Korsgren, O. and M{\"u}ller-Ruchholtz, W.}, title = {Expression of Porcine Pancreatic Islet Antigens Varies and Determines Binding of Human Natural Xenophile Antibodies (NXA)}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45655}, year = {1993}, abstract = {No abstract available}, subject = {Immunbiologie}, language = {en} } @inproceedings{WangUlrichsMuellerRuchholtz1993, author = {Wang, HY and Ulrichs, Karin and M{\"u}ller-Ruchholtz, W.}, title = {Down-Regulation of Xenophile Antibodies by Specific Immunosuppressive Protocols to Facilitate Xenogeneic Organ Transplantation}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45669}, year = {1993}, abstract = {No abstract available}, subject = {Immunbiologie}, language = {en} } @inproceedings{HeiserUlrichsMuellerRuchholtz1994, author = {Heiser, A. and Ulrichs, Karin and M{\"u}ller-Ruchholtz, W.}, title = {Enzyme Activities in Commercial Collagenase Preparations and Their Kinetics During Islet Isolation Procedure}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45633}, year = {1994}, abstract = {No abstract available}, subject = {Transplantation}, language = {en} } @article{DeltzUlrichsSchacketal.1986, author = {Deltz, Eberhard and Ulrichs, Karin and Schack, Thorsten and Friedrichs, Birgit and M{\"u}ller-Ruchholtz, Wolfgang and M{\"u}ller-Hermelink, Hans K. and Thiede, Arnulf}, title = {Graft-versus-host reaction in small bowel transplantation and possibilities for its circumvention}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-64425}, year = {1986}, abstract = {No abstract available}, subject = {D{\"u}nndarm}, language = {en} } @article{LausUlrichsMuellerRuchholtz1988, author = {Laus, R. and Ulrichs, Karin and M{\"u}ller-Ruchholtz, W.}, title = {Carbohydrate-specific human heterophile antibodies in normal human sera that react with xenogeneic cells}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-78271}, year = {1988}, abstract = {Human heterophile antibodies (HHA) that are present in normal human sera (NHS)play an important role in hyperacute xenograft rejection. The aim of this study was to analyze the occurrence, mode of action and molecular specificity of HHA in NHS that are directed against xenogeneic Iymphocytes (isolated from mouse, rat, guinea pig, rabbit, cattle and pig) and isolated rat pancreatic islets. All sera contained variable amounts of HHA that killed the target cells via the classical complement pathway. The cytotoxic activity of these HHA was specifically inhibited by certain carbohydrates (a-D-melibiose, ß-Iactose, ß-gentiobiose, ß-cellobiose, D-mannose, N-acetyl-ß-D-mannosamine and a-D-rhamnose) and by rat IgM. By means of affinity chromatography with immobilized inhibitors we obtained an antibody preparation of mainly IgG type from NHS (up to 3.5 mg/IO ml serum) that reacted strongly with rat lymphocytes and isolated rat pancreatic islets. Though thus far residual xenospecific antibody activity has remained in the sera even after multiple affinity chromatography, these data suggest that specific elimination of HHA is feasible and that it may be thus possible to overcome a major obstacle to xenotransplantation.}, subject = {Immunobiologie}, language = {de} } @article{UlrichsMuellerRuchholtz1991, author = {Ulrichs, Karin and M{\"u}ller-Ruchholtz, Wolfgang}, title = {Modulation of pancreatic islet allo immunogenicity and immunobiological in vitro and in vivo consequences}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-78261}, year = {1991}, abstract = {No abstract available.}, subject = {Immunobiologie}, language = {en} } @article{KrzymanskiWaagaUlrichsetal.1991, author = {Krzymanski, M. and Waaga, A. M. and Ulrichs, Karin and M{\"u}ller-Ruchholtz, Wolfgang}, title = {Long-standing rat kidney graft survival by a combination of organ perfusion with MHC class II monoclonal antibody and immunosuppression with reduced doses of 15-deoxyspergualin.}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-64442}, year = {1991}, abstract = {No abstract available}, subject = {Niere}, language = {en} } @article{WinotoMorbachLeyhausenMuellerRuchholtzetal.1988, author = {Winoto-Morbach, S. and Leyhausen, G. and M{\"u}ller-Ruchholtz, W. and Ulrichs, Karin}, title = {The Electromagnetic Separation Principle: A Basis for Human Pancreatic Islet Transplantation}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-82520}, year = {1988}, abstract = {No abstract available}, subject = {Allergie}, language = {en} } @article{UlrichsWangMuellerBuchholtz1994, author = {Ulrichs, Karin and Wang, H. and M{\"u}ller-Buchholtz, W.}, title = {Down-regulation of xenophile antibodies by 15-deoxyspergualin in an experimental animal model}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-44733}, year = {1994}, abstract = {No abstract available}, subject = {Chirurgie}, language = {en} } @article{WinotoMorbachKroutHeiseretal.1994, author = {Winoto-Morbach, S. and Krout, OS and Heiser, A. and Ulrichs, Karin and M{\"u}ller-Ruchholtz, W.}, title = {Lectin binding to acinar tissue for complete magnetophoretic purification of porcine pancreatic islets depends on the composition and pH of the incubation medium}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45183}, year = {1994}, abstract = {No abstract available}, subject = {Chirurgie}, language = {en} } @article{HeiserUlrichsMuellerRuchholtz1994, author = {Heiser, A. and Ulrichs, Karin and M{\"u}ller-Ruchholtz, W.}, title = {Influence of porcine strain, age, and pH of the isolation medium on porcine pancreatic islet isolation success}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45171}, year = {1994}, abstract = {No abstract available}, subject = {Chirurgie}, language = {en} } @article{KekowUlrichsMuellerRuchholtzetal.1987, author = {Kekow, J. and Ulrichs, Karin and M{\"u}ller-Ruchholtz, W. and Gross, WL}, title = {Pancreas transplantation: a study of insulin secretion in isolated islets of Langerhans and in sera using a new enzyme-linked immunosorbent assay}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45229}, year = {1987}, abstract = {No abstract available}, subject = {Chirurgie}, language = {en} } @article{FalkUlrichsMuellerRuchholtz1987, author = {Falk, W. and Ulrichs, Karin and M{\"u}ller-Ruchholtz, W.}, title = {15-Deoxyspergualin (a new guanidine-like drug) blocks T lymphocyte proliferation}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45215}, year = {1987}, abstract = {No abstract available}, subject = {Chirurgie}, language = {en} } @article{UlrichsKaitschickBartlettetal.1992, author = {Ulrichs, Karin and Kaitschick, J. and Bartlett, R. and M{\"u}ller-Ruchholtz, W.}, title = {Suppression of natural xenophile antibodies with the novel immunomodulating drug leflunomide}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45202}, year = {1992}, abstract = {No abstract available}, subject = {Chirurgie}, language = {en} } @article{UlrichsKellerMuellerRuchholtz1986, author = {Ulrichs, Karin and Keller, R. and M{\"u}ller-Ruchholtz, W.}, title = {Vorkommen und Manipulation von MHC Klasse II Antigenen auf Zellen isolierter Langerhans-Inseln}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45499}, year = {1986}, abstract = {No abstract available}, subject = {Langerhans-Inseln}, language = {de} } @article{WinotoMorbachUlrichsHeringetal.1990, author = {Winoto-Morbach, S. and Ulrichs, Karin and Hering, BJ and Leyhausen, G. and M{\"u}ller-Ruchholtz, W.}, title = {Lectins for electromagnetic purification of islets from humans and large mammals}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45430}, year = {1990}, abstract = {No abstract available}, subject = {Chirurgie}, language = {en} } @article{HeiserMuellerRuchholtzUlrichs1994, author = {Heiser, A. and M{\"u}ller-Ruchholtz, W. and Ulrichs, Karin}, title = {Isolation of Islets of Langerhans: Improvement of the Isolation Technique Using the Pig Model.}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-87765}, year = {1994}, abstract = {During the last view years, interest in pancreatic islet transplantation for the cure of type I diabetes has increased markedly. A serious barrier to clinical islet transplantation is the isolation of a sufficient mass of viable and functional islets. We used a porcine islet isolation model to examine various parameters of the isolation procedure and to improve isolation technique.}, subject = {Langerhans-Inseln}, language = {en} } @article{UlrichsEcksteinHeiseretal.1992, author = {Ulrichs, Karin and Eckstein, V. and Heiser, A. and M{\"u}ller-Ruchholtz, W.}, title = {Die zellvermittelte Immunantwort des menschlichen Transplantat Empf{\"a}ngers gegen xenogenes Antigen (Schwein) ist abh{\"a}ngig vom Spenderkompartiment.}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-86978}, year = {1992}, abstract = {No abstract available.}, subject = {Transplantation}, language = {de} } @article{BreitkreuzUlrichsEcksteinetal.1992, author = {Breitkreuz, A. and Ulrichs, Karin and Eckstein, V. and M{\"u}ller-Ruchholtz, W.}, title = {Induktion von Transplantat-Toleranz gegen Xenoantigen durch eine Pharmakon-Antigen-Kombinationsbehandlung}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-86969}, year = {1992}, abstract = {No abstract available.}, subject = {Transplantat}, language = {de} } @article{HeiserUlrichsWinotoMorbachetal.1992, author = {Heiser, A. and Ulrichs, Karin and Winoto-Morbach, S. and Vanucchi, A. and J{\"a}ger, H. and M{\"u}ller-Ruchholtz, W.}, title = {Erste Kieler Erfahrungen mit 45 Isolierungen von Langerhansinseln aus Schweinepankreas}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-73205}, year = {1992}, abstract = {No abstract available.}, subject = {Langerhans-Inseln}, language = {de} } @article{UlrichsMuellerRuchholtz1993, author = {Ulrichs, Karin and M{\"u}ller-Ruchholtz, W.}, title = {Pharmakologische Beeinflussung nat{\"u}rlicher Antik{\"o}rper als Vorbedingung f{\"u}r die erfolgreiche Xenotransplantation}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-73216}, year = {1993}, abstract = {No abstract available.}, subject = {Heterotransplantation}, language = {de} } @article{HeiserUlrichsGieretal.1993, author = {Heiser, A. and Ulrichs, Karin and Gier, C. and M{\"u}ller-Ruchholtz, W.}, title = {Isolierung Langerhans'scher Inseln aus dem Pankreas von Schweinen: Einfluss biologischer und technischer Parameter auf die Inselausbeite und -integrit{\"a}t}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-73223}, year = {1993}, abstract = {No abstract available.}, subject = {Langerhans-Inseln}, language = {de} } @article{UlrichsHeiserBosseetal.1993, author = {Ulrichs, Karin and Heiser, A. and Bosse, M. and Wacker, H. H. and M{\"u}ller-Ruchholtz, W.}, title = {Histologische Untersuchungen des Schweinepankreas zur Verbesserung der Inselausbeute und -integrit{\"a}t nach Kollagenase-Verdauung}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-73237}, year = {1993}, abstract = {No abstract available.}, subject = {Schwein}, language = {de} } @article{DickneiteSchorlemmerSedlaceketal.1987, author = {Dickneite, G. and Schorlemmer, H. U. and Sedlacek, H. H. and Falk, W. and Ulrichs, Karin and M{\"u}ller-Ruchholtz, W.}, title = {Suppression of macrophage function and prolongation of graft survival by the new guanidinic-like structure, 15-deoxyspergualin}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-86991}, year = {1987}, abstract = {No abstract available.}, subject = {Makrophage}, language = {en} } @article{UlrichsEcksteinTibelletal.1994, author = {Ulrichs, Karin and Eckstein, V. and Tibell, A. and Groth, C. G. and Korsgren, O. and M{\"u}ller-Ruchholtz, W. and Thiede, A.}, title = {Nat{\"u}rliche und induzierte xenoreaktive Antik{\"o}rper vor und nach klinischer Transplantation f{\"o}taler porziner Pankreasinselzellen}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-72967}, year = {1994}, abstract = {No abstract available.}, subject = {Antik{\"o}rper}, language = {de} } @article{UlrichsEcksteinKorsgrenetal.1994, author = {Ulrichs, Karin and Eckstein, V. and Korsgren, O. and Tibell, A. and Groth, C. G. and M{\"u}ller-Ruchholtz, W.}, title = {Characterization of natural and induced human xenophile antibodies before and after transplantation of the fetal porcine endocrine pancreas}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-86985}, year = {1994}, abstract = {No abstract available.}, subject = {Bauspeicheldr{\"u}se}, language = {de} }