@incollection{EpplenAmmerEpplenetal.1991,
  author    = {Epplen, J. T. and Ammer, H. and Epplen, C. and Kammerbauer, C. and Mitreiter, R. and Roewer, L. and Schwaiger, W. and Steimle, V. and Zischler, H. and Albert, E. and Andreas, A. and Beyermann, B. and Meyer, W. and Buitkamp, J. and Nanda, I. and N{\"u}rnberg, P. and Pena, S. D. J. and P{\"o}che, H. and Sprecher, W. and Schartl, Manfred and Weising, K. and Yassouridis, A.},
  title     = {Oligonucleotide fingerprinting using simple repeat motifs: a convenient, ubiquitously applicable method to detect hypervariability for multiple purposes},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-86371},
  publisher      = {Universit{\"a}t W{\"u}rzburg},
  year      = {1991},
  abstract  = {A panel of simple repetitive oligonucleotide probes has been designed and tested for multilocus DNA fingerprinting in some 200 fungal, plant and animal species as well as man. To date at least one of the probes has been found to be informative in each species. The human genome, however, has been the major target of many fingerprintins studies. Using the probe (CAC)5 or (GTG)5, individualization of all humans is possible except for monozygotic twins. Paternity analyses are now perfonned on a routine basis by the use of multilocus fingerprints, inctuding also cases of deficiency, i.e. where one of the parents is not available for analysis. In forensie science stain analysis is feasible in all tissue remains containing nuc)eated cells. Depending on the degree of DNA degradation a variety of oligonucleotides are informative, and they have been proven useful in actual case work. Advantages in comparison to other methods including enzymatic DNA amplification techniques (PCR) are evident. Fingerprint patterns of tumors may be changed due to the gain or loss of chromosomes and/or intrachromosomal deletion and amplification events. Locus-specific probes were isolated from the human (CAC)5/( GTG)5 fingerprint with a varying degree of informativeness (monomorphic versus truly hypervariable markers). The feasibility of three different approaches. for the isolation of hypervariable mono-locus probes was evaluated. Finally, one particular mixed simple (gt)n(ga)m repeat locus in the second intron of the HLA-DRB genes has been scrutinized to allow comparison of the extent of exon-encoded (protein-) polymorphisms versus intronie bypervariability of simple repeats: adjacent to a single gene sequence (e.g. HLA-DRB1*0401) many different length alleles were found. Group-specific structures of basic repeats were identified within the evolutionarily related DRB alleles. As a further application it is suggested here that due to the ubiquitous interspersion of their targets, short probes for simple repeat sequences are especially useful tools for ordering genomic cosmid, yeast artificial chromosome and phage banks.},
  subject      = {DNS},
  language  = {en}
}
@article{LinhardtZiebuhrMeyeretal.1992,
  author    = {Linhardt, F. and Ziebuhr, W. and Meyer, P. and Witte, W. and Hacker, J{\"o}rg},
  title     = {Pulsed-field gel electrophoresis of genomic restriction fragments as a tool for the epidemiological analysis of Staphylococcus aureus and coagulase-negative Staphylococci},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-59811},
  year      = {1992},
  abstract  = {Thirtccn StttJ1hylococcus dw·eus and s: <'pid<'l'· midis strains ohtaincd from nnsc and hand nf twn cmployccs and onc paticnt uf a mcdical ward as weil as two S. hemol.\"licus strains wcrc analyscd according to thcir rcstrktion fmgmcnt lcngth pattcrns ( RFLP) hy pulscd-ficld gcl clcctrophorcsis (PFGE) using thc rcslriction cnzymcs SmaJ and s.. .· tll. Spccics idcntification nf thc isolatcs was pcrformcd hy a systcm which includcs :!O hiochcmical rc"ctions. Furthcrmorc. thc antillintic resistancc pattcrns of thc stmins wcrc dctcrmincd. Whilc scvcral isolatcs cxhihitcd idcnticaf antihiotic susccptihilitics and hiochcmical prnfilcs. diffcrences in thc RFLP wcrc ohtaincd. ln thrcc cascs, S. epiderm{\"u}lis strains colonizing thc skin showcd an idcntical rcstriction profilc as isollltcs from thc mucous mcmhrancs of thc samc pcrson. Wc C(mcludcd that thc analysis of staphylococcal strains hy PFGE is an important cpidcmiolngical tnnl with high discrimination power.},
  subject      = {Infektionsbiologie},
  language  = {en}
}
@article{TackeBentlagemTowartetal.1980,
  author    = {Tacke, Reinhold and Bentlagem, A. and Towart, R. and Meyer, H. and Bossert, F. and Vater, W. and Stoepe, K.},
  title     = {Sila-Analoga von Nifedipin-{\"a}hnlichen 4-Aryl-2.6-dimethyl-1.4-dihydropyridin-3.5-dicarbons{\"a}ure-dialkylestern, I},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-82430},
  year      = {1980},
  abstract  = {no abstract available},
  subject      = {Chemie},
  language  = {de}
}
@article{ZieglerMeyerOtteetal.2022,
  author    = {Ziegler, Alice and Meyer, Hanna and Otte, Insa and Peters, Marcell K. and Appelhans, Tim and Behler, Christina and B{\"o}hning-Gaese, Katrin and Classen, Alice and Detsch, Florian and Deckert, J{\"u}rgen and Eardley, Connal D. and Ferger, Stefan W. and Fischer, Markus and Gebert, Friederike and Haas, Michael and Helbig-Bonitz, Maria and Hemp, Andreas and Hemp, Claudia and Kakengi, Victor and Mayr, Antonia V. and Ngereza, Christine and Reudenbach, Christoph and R{\"o}der, Juliane and Rutten, Gemma and Schellenberger Costa, David and Schleuning, Matthias and Ssymank, Axel and Steffan-Dewenter, Ingolf and Tardanico, Joseph and Tschapka, Marco and Vollst{\"a}dt, Maximilian G. R. and W{\"o}llauer, Stephan and Zhang, Jie and Brandl, Roland and Nauss, Thomas},
  title     = {Potential of airborne LiDAR derived vegetation structure for the prediction of animal species richness at Mount Kilimanjaro},
  series = {Remote Sensing},
  volume    = {14},
  journal   = {Remote Sensing},
  number    = {3},
  issn      = {2072-4292},
  doi       = {10.3390/rs14030786},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-262251},
  year      = {2022},
  abstract  = {The monitoring of species and functional diversity is of increasing relevance for the development of strategies for the conservation and management of biodiversity. Therefore, reliable estimates of the performance of monitoring techniques across taxa become important. Using a unique dataset, this study investigates the potential of airborne LiDAR-derived variables characterizing vegetation structure as predictors for animal species richness at the southern slopes of Mount Kilimanjaro. To disentangle the structural LiDAR information from co-factors related to elevational vegetation zones, LiDAR-based models were compared to the predictive power of elevation models. 17 taxa and 4 feeding guilds were modeled and the standardized study design allowed for a comparison across the assemblages. Results show that most taxa (14) and feeding guilds (3) can be predicted best by elevation with normalized RMSE values but only for three of those taxa and two of those feeding guilds the difference to other models is significant. Generally, modeling performances between different models vary only slightly for each assemblage. For the remaining, structural information at most showed little additional contribution to the performance. In summary, LiDAR observations can be used for animal species prediction. However, the effort and cost of aerial surveys are not always in proportion with the prediction quality, especially when the species distribution follows zonal patterns, and elevation information yields similar results.},
  language  = {en}
}
@article{SchulmeyerFaschingHaeberleetal.2023,
  author    = {Schulmeyer, Carla E. and Fasching, Peter A. and H{\"a}berle, Lothar and Meyer, Julia and Schneider, Michael and Wachter, David and Ruebner, Matthias and P{\"o}schke, Patrik and Beckmann, Matthias W. and Hartmann, Arndt and Erber, Ramona and Gass, Paul},
  title     = {Expression of the immunohistochemical markers CK5, CD117, and EGFR in molecular subtypes of breast cancer correlated with prognosis},
  series = {Diagnostics},
  volume    = {13},
  journal   = {Diagnostics},
  number    = {3},
  issn      = {2075-4418},
  doi       = {10.3390/diagnostics13030372},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-304987},
  year      = {2023},
  abstract  = {Molecular-based subclassifications of breast cancer are important for identifying treatment options and stratifying the prognosis in breast cancer. This study aimed to assess the prognosis relative to disease-free survival (DFS) and overall survival (OS) in patients with triple-negative breast cancer (TNBC) and other subtypes, using a biomarker panel including cytokeratin 5 (CK5), cluster of differentiation 117 (CD117), and epidermal growth factor receptor (EGFR). This cohort-case study included histologically confirmed breast carcinomas as cohort arm. From a total of 894 patients, 572 patients with early breast cancer, sufficient clinical data, and archived tumor tissue were included. Using the immunohistochemical markers CK5, CD117, and EGFR, two subgroups were formed: one with all three biomarkers negative (TBN) and one with at least one of those three biomarkers positive (non-TBN). There were significant differences between the two biomarker subgroups (TBN versus non-TBN) in TNBC for DFS (p = 0.04) and OS (p = 0.02), with higher survival rates (DFS and OS) in the non-TBN subgroup. In this study, we found the non-TBN subgroup of TNBC lesions with at least one positive biomarker of CK5, CD117, and/or EGFR, to be associated with longer DFS and OS.},
  language  = {en}
}