@article{HommersGloth1978,
author = {Hommers, Wilfried and Gloth, Ingola},
title = {Alternativenart, pers{\"o}nliche Gl{\"u}ckszahl und magisch animistische Begr{\"u}ndungen von Entscheidungen bei Risiko},
url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-43822},
year = {1978},
abstract = {Durch Variation des Konfliktgehalts zwischen zwei Alternativen und damit der Begr{\"u}ndbarkeit von Entscheidungen sollte gepr{\"u}ft werden, ob das Auftreten magisch-animistischer Begr{\"u}ndungen bei Schulkindern nur Begr{\"u}ndungsschwierigkeiten anzeigt und nicht magisch-animistisches Denken. Mit Hilfe einer erfragten Gl{\"u}ckszahl beim W{\"u}rfeln sollte außerdem die Validit{\"a}t des magisch-animistisehen Gehalts von derartigen Begr{\"u}ndungen untersucht werden. Es zeigte sich bei 61 11j{\"a}hrigen Vpn, daß magisch-animistisch klassifizierte Antworten mit dem Konfliktgehalt der Alternativen zusammenhingen und bei eine Gl{\"u}ckszahl besitzenden Vpn, die diese in den Entscheidungen ber{\"u}cksichtigen, h{\"a}ufiger vorkommen als bei Vpn zweier Vergleichsgruppen.},
subject = {Angewandte Psychologie},
language = {de}
}
@article{Scheer1978,
author = {Scheer, Ulrich},
title = {Changes of nucleosome frequency in nucleolar and non-nucleolar chromatin as a function of transcription: an electron microscopic study},
url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-39750},
year = {1978},
abstract = {The morphology of nucleolar and non-nucleolar (Iampbrush chromosome loops) chromatin was studied in the electron microscope during states of reduced transcriptional activity in amphibian oocytes (Xenopus laevis, Triturus alpestris, T. cristatus). Reduced transcriptional activity was observed in maturing stages of oocyte development and after treatment with an inhibitor, actinomycin D. Strands of nucleolar chromatin appear smooth and thin, and contain only few, if any, nucleosomal particles in the transcribed units. This is true whether they are densely or only sparsely covered with lateral ribonucleoprotein fibrils. This smooth and non-nucleosomal character is also predominant in the interspersed, apparently nontranscribed rDNA spacer regions. During inactivation, however, nucleolar chromatin frequently and progressively assumes a beaded appearance in extended fibril-free-that is, apparently nontranscribed - regions. I n either fUll-grown 00- cytes or late after drug treatment, most of the nucleolar chromatin is no longer smooth and thin, but rather shows a beaded configuration indistinguishable from inactive non - nucleolar chromatin. In many chromatin strands, transitions of fibril-associated regions of smooth character into beaded regions wihout lateral fibrils are seen. Similarly, in the non-nucleolar chromatin of the retracting lampbrush chromosome loops, reduced transcriptional activity is correlated with a change from smooth to beaded morphology. Here, however, beaded regions are also commonly found interspersed between the more or less distant bases of the lateral fibrils, the putative transcriptional complexes. I n both sorts of chromatin, detergents (in particular Sarkosyl) that remove most of the chromatin proteins including histones from the DNA axis but leave the RNA polymerases of the transcriptional complexes attached were used to discriminate between polymerases and nucleosomal particles. The results suggest that nucleosomes are absent in heavily transcribed chromatin regions but are reformed after inactivation. In contrast to the findings with inactivated nucleolar genes, in lampbrush chromosome loops the beaded nucleosomal configuration appears to be assumed also in regions within transcriptional units that, perhaps temporarily, are not involved in transcription.},
language = {en}
}
@article{Burschka1978,
author = {Burschka, Christian},
title = {Intermolekulare Koordination bei zyklischen Esternder stibonigen und der thiostibonigen S{\"a}ure},
url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-31374},
year = {1978},
abstract = {Die Struktur von EinkristalIen des 2-Methoxi-l,3, 2-benzodioxastibols und des 2-Methylthio-l, 3, 2-benzodithiastibols konnte {\"u}ber R{\"o}ntgendiffraktometermessungen ermittelt werden. Die Verbindungen kristallisieren beide monoklin mit Elementarzellen, die jeweils 4 Formeleinheiten enthalten, sie sind jedoch nicht isomorph. Als Raumgruppe ergibt sich P21/n bzw. P21/c. Ungew{\"o}hnlich kurze intermolekulare Antimon-Chalkogen-Abst{\"a}nde lassen in der Struktur des Oxastibols koordinative Bindungen erkennen, die in dieser St{\"a}rke beim Thiastibol nicht auftreten.},
subject = {Chemie},
language = {de}
}
@inproceedings{FrankeZentgrafScheer1978,
author = {Franke, Werner W. and Zentgraf, Hanswalter and Scheer, Ulrich},
title = {Supranucleosomal and non-nucleosomal chromatin configurations},
url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-39447},
year = {1978},
abstract = {A significant contribution to the understanding of chromatin organization was the d iscovery of the nucleosome as a globular repeating unit of the package of DNA (Hewish and Burgoyne, 1973; Woodcock, 1973; Kornberg, 1974; Olins and Olins, 1974; for review see Oudet et al., 1978 a) . In accord with the original definition and in ag reement with most workers in this field of research we identify a nucleosome as a spheric alor slightly oblate gr anular particle 10-13 nm in diameter, containing about 200 base pairs of DNA and two of each of the four his tones H2a, H2b, H3 and H4. It is this structure in which the bulk of the nuclear chroma tin is organized in most eukaryotic cells, with the exception of the dinofl age llates (Rae and Steele, 1977; dinofl agellate DNA, however, c an be packed into nucleosoma l structures in vitro by addition of the appropriate amounts of histones;the same reference). Although it seems clear from the work reported that condensed and transcriptiona lly inactive chroma tin is contained in nucleosomes as the principle for first order p acking of DNA there are two important questions onto which we are focusing in the present study: ( i ) What is the higher order of p a cking present in - and perhaps typical-of - the condensed sta te of chromatin, and (ii) what is the specific form of arrangement of transcriptionally a ctive chromatin?},
language = {en}
}
@article{LutzSchlatter1978,
author = {Lutz, Werner K. and Schlatter, C.},
title = {A closed inhalation system for pharmacokinetic and metabolism studies of volatile compounds with small laboratory animals},
url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-80145},
year = {1978},
abstract = {In the inhalation system described an animal can be kept in the same atmosphere of a 2-liter desiccator for up to 24 h. The expired carbon dioxide is adsorbed with soda lime and the resulting reduced pressure is balanced by a supply of oxygen also used for the inflow of the chemical to be investigated. Urine and faeces can be collected ~eparately and the system allows a periodical control of the concentration of the chemical by sampling the air with needle and syringe.},
subject = {Toxikologie},
language = {en}
}
@article{ChristlBuchner1978,
author = {Christl, Manfred and Buchner, Wolfgang},
title = {13C-NMR-Spektren von Tetracyclo[4.1.0.02,4.03,5]heptanen, Tetracyclo[5.1.0.02,4.03,5]octanen und Tricyclo[4.1.0.02,7]hept-3-enen. Ungew{\"o}hnliche beta- und gamma-Substituenteneffekte},
url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-30087},
year = {1978},
abstract = {No abstract available},
language = {de}
}
@article{RunggerCrippaTrendelenburgetal.1978,
author = {Rungger, M. and Crippa, M. and Trendelenburg, M. F. and Scheer, Ulrich and Franke, Werner W.},
title = {Visualization of rDNA spacer transcription in Xenopus oocytes treated with fluorouridine},
url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-33082},
year = {1978},
abstract = {Under the intluence of 5-tluoro-uridine, the ultrastructure of the rDNA transcription units in Xenopus oocytes is altered. Whereas part of the matrix units maintains anormal aspect or shows various degrees of inhibition, in a strong proportion of the transcription units the alternating pattern of matrix units and fibril-free spacer regions is no longer recognized. Transcriptional complexes are found along the entire DNP axis, including the regions of the spacers. These observations support biochemical data on transcription in rDNA spacer region.},
language = {en}
}
@article{KrohneFrankeScheer1978,
author = {Krohne, Georg and Franke, Werner W. and Scheer, Ulrich},
title = {The major polypeptides of the nuclear pore complex},
url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-33078},
year = {1978},
abstract = {Nuclear envelopes of maturing oocytes of various amphibia contain an unusually high number of pore complexes in very close packing. Consequently, nuclear envelopes , which can be manually isolated in great purity, provide a remarkable enrichment of nuclear pore complex material, relative to membranous and other interporous structures. When the polypeptides of nuclear envelopes isolated from oocytes of Xenopl/s la evis and Triturus alpestris are examined by gel electrophoresis, visualized either by staining with Coomassie blue or by radiotluorography after in vitro reaction with [3H]dansyl chloride , a characteristic pattern is obtained (10 major and 15 minor bands). This polypeptide pattern is radically different from that of the nuclear contents isolated from the same cell. Extraction of the nuclear envelope with high salt concentrations and moderateIy ac tive detergents such as Triton X- 100 results in the removal of membrane material but leaves most of the non-membranous structure of the pore complexes. The dry weight of the pore complex (about 0.2 femtograms) remains essentially unchanged during such extractions as measured by quantitative electron microscopy . The extracted preparations which are highly enriched in nuclear pore complex material contain only two major polypeptide components with apparent molecular weights of 150000 and 73000. Components of such an electrophoretic mobility are not present as major bands , if at all , in nuclear contents extracted in the same way. lt is concluded that these two polypeptides are the major constituent protein(s) of the oocyte nuclear pore complex and are specific for this structure. When nuclear envelopes are isolated from rat liver and extracted with high salt buffers and Triton X- 100 similar bands are predominant, but two additional major components of molecular weights of 78000 and 66000 are also recognized. When the rat liver nuclear membranes are further subfractionated material enriched in the 66000 molecular weight component can be separated from the membrane material, indicating that this is relatively loosely associated material , probably a part of the nuclear matrix . The results suggest that the nuclear pore complex is not only a characteristic ubiquitous structure but also contains similar, if not identical , skeletal proteins that are remarkably re sistant to drastic changes of ionic strength as weil as to treatments with detergents and thiol reagents.},
language = {en}
}
@article{ScheerZentgraf1978,
author = {Scheer, Ulrich and Zentgraf, Hanswalter},
title = {Nucleosomal and supranucleosomal organization of transcriptionally inactive rDNA circles in Dytiscus oocytes},
url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-33188},
year = {1978},
abstract = {Oocytes of the water beetle, Dytiscus marginalis, contain large amounts of rDNA most of which is present in the form of rings containing one or several pre-rRNA genes. Electron microscopy of spread preparations of vitellogenic oocytes has shown that the rDNA is extended in chromatin rings with transcribed pre- rRNA genes and is not packed into nucleosomes (Trendelenburg eta!. , 1976). When similar preparations are made from previtellogenic ooytes in which a large proportion of the nuc1eolar chromatin is transcriptionally inactive, a different morphological form of this chromatin is recognized. In contrast to the transcribed chromatin rings the inactive nucleolar chromatin circles show the characteristic beaded configuration, indicative of nucleosomal packing. Nuc1eosomal packing is also indicated by the comparison of the lengths of these chromatin rings with both iso lated rDNA circ1es and transcribed chromatin rings. In addition, these inactive nuc1eofilaments often appear to be compacted into globular higher order structures of diameters from 21 to 34nm, each composed of an aggregate of 6-9 nuc1eosomes. While the estimated reduction of the overall length of rDNA, as seen in our preparations, is, on the average, only 2.2 - 2.4 fold in the nuc1eosomal state it is 10- 13 fold when supranuc1eosomal globules are present. These data show that the extrachromosomal rDNA of these oocytes goes through a cycle of condensation and extensio n, as a function of the specific transcriptional activity, and that the beaded state described here is exc1usively found in the non-transcribed state.},
language = {en}
}
@article{Wilhelm1978,
author = {Wilhelm, Gernot},
title = {D{\´e}couvertes {\´e}pigraphiques {\`a} Kāmid el-Lōz},
url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-78183},
year = {1978},
abstract = {No abstract available},
subject = {Geschichte},
language = {fr}
}