TY  - JOUR
A1  - Weis, Matthias
A1  - Shan, Junwen
A1  - Kuhlmann, Matthias
A1  - Jungst, Tomasz
A1  - Tessmar, Jörg
A1  - Groll, Jürgen
T1  - Evaluation of hydrogels based on oxidized hyaluronic acid for bioprinting
JF  - Gels
N2  - In this study, we evaluate hydrogels based on oxidized hyaluronic acid, cross-linked with adipic acid dihydrazide, for their suitability as bioinks for 3D bioprinting. Aldehyde containing hyaluronic acid (AHA) is synthesized and cross-linked via Schiff Base chemistry with bifunctional adipic acid dihydrazide (ADH) to form a mechanically stable hydrogel with good printability. Mechanical and rheological properties of the printed and casted hydrogels are tunable depending on the concentrations of AHA and ADH cross-linkers.
KW  - biofabrication
KW  - bioprinting
KW  - hyaluronic acid
Y1  - 2018
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-197600
SN  - 2310-2861
VL  - 4
IS  - 4
ER  - 
TY  - JOUR
A1  - McColl, Erin
A1  - Groll, Jürgen
A1  - Jungst, Tomasz
A1  - Dalton, Paul D.
T1  - Design and fabrication of melt electrowritten tubes using intuitive software
JF  - Materials and Design
N2  - This study approaches the accurate continuous direct-writing onto a cylindrical collector from a mathematical perspective, taking into account the winding angle, cylinder diameter and length required for the final 3D printed tube. Using an additive manufacturing process termed melt electrowriting (MEW), porous tubes intended for tissue engineering applications are fabricated from medical-grade poly(ε-caprolactone) (PCL), validating the mathematically-derived method. For the fabricated tubes in this study, the pore size, winding angle and printed length can all be planned in advance and manufactured as designed. The physical dimensions of the tubes matched theoretical predictions and mechanical testing performed demonstrated that variations in the tubular morphology have a direct impact on their strength. MEWTubes, the web-based application developed and described here, is a particularly useful tool for planning the complex continuous direct writing path required for MEW onto a rotating, cylindrical build surface.
KW  - additive manufacturing
KW  - 3D printing
KW  - electrohydrodynamic printing
KW  - biomaterials
KW  - polycaprolactone
Y1  - 2018
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-223891
VL  - 155
ER  -