TY - JOUR A1 - Kosmala, Aleksander A1 - Gruschwitz, Philipp A1 - Veldhoen, Simon A1 - Weng, Andreas Max A1 - Krauss, Bernhard A1 - Bley, Thorsten Alexander A1 - Petritsch, Bernhard T1 - Dual-energy CT angiography in suspected pulmonary embolism: influence of injection protocols on image quality and perfused blood volume JF - The International Journal of Cardiovascular Imaging N2 - Abstract To compare intravenous contrast material (CM) injection protocols for dual-energy CT pulmonary angiography (CTPA) in patients with suspected acute pulmonary embolism with regard to image quality and pulmonary perfused blood volume (PBV) values. A total of 198 studies performed with four CM injection protocols varying in CM volume and iodine delivery rates (IDR) were retrospectively included: (A) 60 ml at 5 ml/s (IDR = 1.75gI/s), (B) 50 ml at 5 ml/s (IDR = 1.75gI/s), (C) 50 ml at 4 ml/s (IDR = 1.40gI/s), (D) 40 ml at 3 ml/s (IDR = 1.05gI/s). Image quality and PBV values at different resolution settings were compared. Pulmonary arterial tract attenuation was highest for protocol A (397 ± 110 HU; p vs. B = 0.13; vs. C = 0.02; vs. D < 0.001). CTPA image quality of protocol A was rated superior compared to protocols B and D by reader 1 (p = 0.01; < 0.001), and superior to protocols B, C and D by reader 2 (p < 0.001; 0.02; < 0.001). Otherwise, there were no significant differences in CTPA quality ratings. Subjective iodine map ratings did not vary significantly between protocols A, B, and C. Both readers rated protocol D inferior to all other protocols (p < 0.05). PBV values did not vary significantly between protocols A and B at resolution settings of 1, 4 and 10 (p = 0.10; 0.10; 0.09), while otherwise PBV values displayed a decreasing trend from protocol A to D (p < 0.05). Higher CM volume and IDR are associated with superior CTPA and iodine map quality and higher absolute PBV values. KW - CT KW - dual-energy CT KW - pulmonary embolism KW - contrast media Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-314739 SN - 1569-5794 SN - 1573-0743 VL - 36 IS - 10 ER - TY - JOUR A1 - Hartrampf, Philipp E. A1 - Petritsch, Bernhard A1 - Buck, Andreas K. A1 - Serfling, Sebastian E. T1 - Pitfalls in PSMA-PET/CT: Intensive bone-marrow uptake in a case with polycythaemia vera JF - European Journal of Nuclear Medicine and Molecular Imaging N2 - No abstract available. KW - bone-marrow Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-235608 SN - 1619-7070 VL - 48 ER -