TY  - JOUR
A1  - Banales, Jesus M.
A1  - Cardinale, Vincenzo
A1  - Carpino, Guido
A1  - Marzioni, Marco
A1  - Andersen, Jesper B.
A1  - Invernizzi, Pietro
A1  - Lind, Guro E.
A1  - Folseraas, Trine
A1  - Forbes, Stuart J.
A1  - Fouassier, Laura
A1  - Geier, Andreas
A1  - Calvisi, Diego F.
A1  - Mertens, Joachim C.
A1  - Trauner, Michael
A1  - Benedetti, Antonio
A1  - Maroni, Luca
A1  - Vaquero, Javier
A1  - Macias, Rocio I. R.
A1  - Raggi, Chiara
A1  - Perugorria, Maria J.
A1  - Gaudio, Eugenio
A1  - Boberg, Kirsten M.
A1  - Marin, Jose J. G.
A1  - Alvaro, Domenico
T1  - Cholangiocarcinoma: current knowledge and future perspectives consensus statement from the European Network for the Study of Cholangiocarcinoma (ENS-CCA)
JF  - Nature Reviews Gastroenterology & Hepatology
N2  - Cholangiocarcinoma (CCA) is a heterogeneous group of malignancies with features of biliary tract differentiation. CCA is the second most common primary liver tumour and the incidence is increasing worldwide. CCA has high mortality owing to its aggressiveness, late diagnosis and refractory nature. In May 2015, the "European Network for the Study of Cholangiocarcinoma" (ENS-CCA: www.enscca.org or www.cholangiocarcinoma.eu) was created to promote and boost international research collaboration on the study of CCA at basic, translational and clinical level. In this Consensus Statement, we aim to provide valuable information on classifications, pathological features, risk factors, cells of origin, genetic and epigenetic modifications and current therapies available for this cancer. Moreover, future directions on basic and clinical investigations and plans for the ENS-CCA are highlighted.
KW  - primary sclerosing cholangitis
KW  - growth-factor-receptor
KW  - biliary-tract cancer
KW  - epithelial-mesenchymal transition
KW  - fine-needle-aspiration
KW  - human intrahepatic cholangiocarcinoma
KW  - induce cyclooxygenase-2 expression
KW  - human cholangiocellular carcinoma
KW  - nucleoside transporter
KW  - hepatic stellate cells
Y1  - 2016
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-189077
VL  - 13
IS  - 5
ER  -