TY  - JOUR
A1  - Huttelmaier, Johanna
A1  - Benoit, Sandra
A1  - Goebeler, Matthias
T1  - Comorbidity in bullous pemphigoid: up-date and clinical implications
JF  - Frontiers in Immunology
N2  - Bullous pemphigoid is the most common autoimmune blistering disease in industrialized countries and particularly affects the elderly. In this patient population, comorbid diseases are frequent and may complicate management and treatment of bullous pemphigoid. A better understanding why distinct diseases are more frequent in bullous pemphigoid patients may lead to new pathophysiological insights and - as a consequence - result in better patient care. The association of bullous pemphigoid with neurological and psychiatric diseases is well known and confirmed by several case-control studies. Association with further diseases such as malignancy and metabolic diseases are still discussed controversially. In recent years new relationships between bullous pemphigoid and autoimmune as well as inflammatory skin diseases have been reported. This review provides a systematic overview on studies addressing comorbidity in bullous pemphigoid patients. Increasing the awareness of both, common and rare comorbid diseases, may enable clinicians to optimize patient support and individualized treatment of bullous pemphigoid.
KW  - bullous pemphigoid
KW  - autoimmune skin blistering disease
KW  - comorbidity
KW  - neurologic disease
KW  - metabolic disease
KW  - malignancy
KW  - inflammatory disease
Y1  - 2023
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-321671
VL  - 14
ER  -