TY  - JOUR
A1  - Hayden, Markus C.
A1  - Limbach, Matthias
A1  - Schuler, Michael
A1  - Merkl, Steffen
A1  - Schwarzl, Gabriele
A1  - Jakab, Katalin
A1  - Nowak, Dennis
A1  - Schultz, Konrad
T1  - Effectiveness of a three-week inpatient pulmonary rehabilitation program for patients after COVID-19: a prospective observational study
JF  - International Journal of Environmental Research and Public Health
N2  - For COVID-19 patients who remain symptomatic after the acute phase, pulmonary rehabilitation (PR) is recommended. However, only a few studies have investigated the effectiveness of PR, especially considering the duration between the acute phase of COVID-19 and the onset of rehabilitation, as well as the initial severity. This prospective observational study evaluated the efficacy of PR in patients after COVID-19. A total of 120 still-symptomatic patients referred for PR after overcoming acute COVID-19 were asked to participate, of whom 108 (mean age 55.6 ± 10.1 years, 45.4% female) consented. The patients were assigned to three groups according to the time of referral and initial disease severity (severe acute; severe after interval; mild after interval). The primary outcome was dyspnea. Secondary outcomes included other respiratory disease symptoms, physical capacity, lung function, fatigue, quality of life (QoL), depression, and anxiety. Furthermore, patients rated the overall effectiveness of PR and their subjective change in health status. At the end of PR, we detected improvements with large effect sizes in exertional dyspnea, physical capacity, QoL, fatigue, and depression in the overall group. Other parameters changed with small to medium effect sizes. PR was effective after acute COVID-19 in all three groups analyzed.
KW  - COVID-19
KW  - pulmonary rehabilitation
KW  - course of recovery
KW  - inpatient rehabilitation
Y1  - 2021
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-245170
SN  - 1660-4601
VL  - 18
IS  - 17
ER  - 
TY  - JOUR
A1  - Rieth, Thorsten
A1  - Tober, Natalie
A1  - Limbach, Daniel
A1  - Haspel, Tobias
A1  - Sperner, Marcel
A1  - Schupp, Niklas
A1  - Wicker, Philipp
A1  - Glang, Stefan
A1  - Lehmann, Matthias
A1  - Detert, Heiner
T1  - Impact of substitution pattern and chain length on the thermotropic properties of alkoxy-substituted triphenyl-tristriazolotriazines
JF  - Molecules
N2  - Tristriazolotriazines (TTTs) with a threefold alkoxyphenyl substitution were prepared and studied by DSC, polarized optical microscopy (POM) and X-ray scattering. Six pentyloxy chains are sufficient to induce liquid-crystalline behavior in these star-shaped compounds. Thermotropic properties of TTTs with varying substitution patterns and a periphery of linear chains of different lengths, branching in the chain and swallow-tails, are compared. Generally, these disks display broad and stable thermotropic mesophases, with the tangential TTT being superior to the radial isomer. The structure–property relationships of the number of alkyl chains, their position, length and structure were studied.
KW  - star-shaped compounds
KW  - discotic liquid crystals
KW  - X-ray diffraction
KW  - differential scanning calorimetry
KW  - polarizing optical microscopy
KW  - swallow-tail
KW  - heterocycles
KW  - structure–property relation
Y1  - 2020
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-220019
SN  - 1420-3049
VL  - 25
IS  - 23
ER  -