TY  - JOUR
A1  - Jaggi, W.
A1  - Lutz, Werner K.
A1  - Lüthy, J.
A1  - Zweifel, U.
A1  - Schlatter, C.
T1  - In vivo covalent binding of aflatoxin metabolites isolated from animal tissue to rat-liver DNA
N2  - Ring-labelled [\(^{14}\)C)aflatoxin B\(_1\) (AFB\(_1\)), prepared by biosynthesis. or generally labelled [\(^3\)H]AFB\(_1\) was administered by oral gavage to young adult male rats. After 6 hr. the liver was removed and two fractions were isolated, namely macromolecules, which contamed about 3 % of the initial dose of AFB\(_1\) radioactivity. and water-soluble, low-molecular aftatoxin conjugates containing about0·2% of the administered radioactivity. These two fractions were administered orally to other rats in order to determine the potential of radioactive aftatoxin residues for covalent binding to DNA. Such binding can be used as an indicator for carcinogenic potency. Liver DNA was isolated 9-12 hr after admmistration of the aflatoxin derivatives and in no case was any radioactivity detected on the DNA. It can be deduced on the basis of the limit of detection of radioactivity on the DNA, that macromolecule bound AFB\(_1\) derivatives are at least 4000 times less active than AFB\(_1\) with respect to covalent binding to rat-liver DNA. and that the water-soluble conjugates are at least 100 times less potent than AFB, itself. It is concluded that the carcinogenic risk for humans who consume liver or meat. containing such aflatoxin residues is negligible when compared with the risk from intake of aftatoxins in other food items.
KW  - Toxikologie
Y1  - 1980
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-61101
ER  - 
TY  - JOUR
A1  - Viviani, A.
A1  - Däniken, A. von
A1  - Schlatter, C.
A1  - Lutz, Werner K.
T1  - Effect of selected induction of microsomal and nuclear aryl hydrocarbon monooxygenase and epoxide hydrolase as well as cytoplasmic glutathione S-epoxide transferase on the covalent binding of the carcinogen benzo(a)pyrene to rat liver DNA in vivo
N2  - Groups of four adult male rats [ZUR:SIV -Z] were pretreated with corn oil (control; 2 ml/kg/day i. p. for 3 days), trans-stilbene-oxide (SO; 200 mg/kg/day i. p. for 2 days), 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD; 10 \(\mu\)g/kg i. p. once, 4 days before killing), phenobarbital (PB; 1 gjliter in the drinking water for 8 days), and dieldrin (20 mg/kg/day i. p. for 3 or 9 days). They received an injection of [G-\(^3\)H]benzo(a)pyrene (BaP, 31 \(\mu\)g/kg, 7.4. 10\(^9\) dpm/kg; i. v.) 16 h before killing. In the liver of each rat, five enzymatic activities and the covalent binding of BaP to DNA have been determined. The rnicrosomal aryl hydrocarbon monooxygenase activity (AHM) ranged frorn 75% of control (SO) to 356% (TCDD), the nuclear AHM from 63% (SO) to 333% (TCDD). Microsomal epoxide hydrolase activity (EH) was induced up to 238% (PB), nuclear EH ranged from 86% (TCDD) to 218% (PB). A different extent of induction was observed in the two compartments. Highest induction of glutathione S-epoxide transferase activity (GST) was found with PB (202%). The DNA binding of BaP was modulated within 79% (dieldrin, 9 days) and 238% of control (TCDD). An enzyme digest of control DNA was analysed by Sephadex LH-20 chromatography. Multiple linear regression analysis with all data expressedas o/o of control yielded the following equation: DNA Binding = 1.49 · Microsomal AHM- 1.07 · Nuclear AHM+ 0.33 · Microsomal EH- 0.52 · N uclear EH+ 0.11 · Cytoplasmic GST + 58.2. From this analysis it is concluded that (1) AHM located in the endoplasmic reticulum is most important in the formation of DNA-binding metabolites, (2) EH in the same compar.tment is not determinative in thls respect nor has it a protective effect, (3) both membrane-bound enzyme activities located in the nucleus may inactivate potential ultimate carcinogens, and ( 4) cytoplasmic GST probably cannot reduce DNA binding due to its subcellular localization.
KW  - Toxikologie
KW  - Carcinogen
KW  - Benzo(a)pyrene-DNA binding
KW  - Enzyme induction
KW  - Aryl hydrocarbon rnonooxygenase
KW  - Epoxide hydrolase
KW  - Glutathione Stransferase
Y1  - 1980
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-61114
ER  - 
TY  - JOUR
A1  - Ackermann, J.
A1  - Tacke, Reinhold
A1  - Wannagat, U.
A1  - Koke, U.
A1  - Meyer, F.
T1  - Sila-Analoga des Chlorphencyclans
T1  - Sila Analogues of Chlorphencyclane
N2  - Sila-Chlorphencyclan (8b), ein Sila-Analogon des Chlorphencyclans (8a), die Derivate 7 und 9, deren Ammoniumsalze 11, 12, 13 und 14b, das Hydrolyseprodukt 10 sowie die Vorstufen 3-6 wurden erstmalig dargestellt. Die neuen Verbindungen wurden in ihren chemischen und physikalischen Eigenschaften charakterisiert, ihre Struktur wurde sichergestellt. Chlorphencyclan, Sila-Chlorphencyclan und einige seiner Derivate wurden vergleichend pharmakologisch und toxikologisch untersucht.
N2  - Silachlorphencyclane (8b), a sila analogue of chlorphencyclane (8a), the derivatives 7 and 9, their amrnonium salts 11, 12, 13 and 14b, the product of hydro Iysis 10, as weil as the precursors ~ were synthesized. The new compounds were characterized by their chemical and physical properties. The pharmacological and toxicological properties of chlorphencyclane, silachlorphencyclane and some derivatives were investigated.
KW  - Anorganische Chemie
Y1  - 1980
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-63633
ER  - 
TY  - JOUR
A1  - Tacke, Reinhold
A1  - Heeg, E.
A1  - Berndt, B
T1  - Sila-Analogon des Rythmols
T1  - Sila Analogue of Rythmol
N2  - Sila-Rythmol (llb), ein Sila-Analogon des Antiarrhythmieums Rythmol (lla), wurde erstmalig dargestellt. llb sowie die Vorstufen und Nebenprodukte 4, 5, 6, 7, 9b und lOb wurden in ihren physikalischen und chemischen Eigenschaften charakterisiert und in ihrer Struktur sichergestellt. Die pharmakologischen und toxikologischen Eigenschaften der Analoga lla und llb wurden vergleichend untersucht.
N2  - Silarythmol (llb), a sila analogue of the antiarrhythmic rythmol (lla), was synthesized for the first time. llb as weil as the precursors and byproducts 4, 5, 6, 7, 9b, and lOb were characterized by their physical and chemical properties. The pharmacological and toxicological properties of the analogues lla and llb were also investigated.
KW  - Anorganische Chemie
Y1  - 1980
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-63642
ER  - 
TY  - JOUR
A1  - Tacke, Reinhold
A1  - Strecker, M.
A1  - Sheldrick, W. S.
A1  - Ernst, L.
A1  - Heeg, E.
A1  - Berndt, B.
A1  - Knapstein, C.-M.
A1  - Niedner, R.
T1  - Sila-Pridinol und Pridinol: Darstellung und Eigenschaften sowie Strukturen im kristallinen und gelösten Zustand
T1  - Sila-Pridinol and Pridinol: Preparation and Properties as weil as Structures ln the Solid Stateand in Solution
N2  - Sila-Pridinol (2 b), ein Sila-Analogon des Anticholinergicums Pridinol (2a), wurde auf zwei verschiedenen Wegen dargestellt. Die Kristall- und Molekülstrukturen von 2 a und 2 b wurden röntgenstrukturanalytisch bestimmt. 2a bildet im festen Zustand intramolekulare Wasserstoffbrückenbindungen aus, während sich in kristallinem 2 b zentrosymmetrische, durch intermolekulare H-Brückenbindungen verknüpfte cyclische Dimere finden. IR- und \8^1\)H-NMR-spektroskopische sowie kryoskopische Untersuchungen ergaben Informationen über die Strukturen von 2a und 2 b in verschiedenen Lösungsmitteln. - Die pharmakologischen und toxikologischen Eigen" schaften von 2a und 2b wurden unter dem Gesichtspunkt bekannter Struktur-Wirkungs-Beziehungen vergleichend untersucht. 2 b erwies sich als ein etwa fünfmal so starkes Anticholincrgicum wie 2a.
N2  - Sila"pridinol (2 b), a sila"analogue of the anticholinergic pridinol (2a). was prepared by two different routes. The crystal and molecular structures of 2 a and 2 b were determined by X-ray structural analyses. 2a forms intramolecular hydrogen bonds in the solid state, whereas centrosymrnetric cyclic dimers linked through intermolecular hydrogen bonds are observed for crystalline 2 b. IR- and \(^1\)H NMR spectroscopic as weil as cryoscopic studies yielded information ab out the structures of 2a and 2 bin different solvents. - The pharmacological and toxicological properties of2a and 2b were compared with one another on the basis ofknown structure-activity relationships. The anticholinergic properties of 2b were found tobe about five times as strong as those of 2a.
KW  - Anorganische Chemie
Y1  - 1980
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-63654
ER  - 
TY  - JOUR
A1  - Tacke, Reinhold
A1  - Zimonyi-Hegedüs, E.
A1  - Strecker, M.
A1  - Heeg, E.
A1  - Berndt, B.
A1  - Langner, R.
T1  - Sila-Analogon des Tiemoniumiodids
T1  - Sila-Analogue of Tiemonium Iodide
N2  - Sila-Tiemoniumiodid (16b), ein Sila-Analogon des Anticholinergicums Tiemoniumiodid (16a), und das Sila-Analogon 14b der entsprechenden Tiemonium-Base 14a wurden erstmalig synthetisiert.14b und 16b sowie die Vorstufen 10-13 und 15 wurden in ihren physikalischen und chemischen Eigenschaften charakterisiert und in ihrer Struktur durch Elementaranalysen sowie \(^1\)H-NMR- und Massenspektren sichergestellt. Die spasmolytischen Eigenschaften der Paare 14a/14b und 16a/16b wurden am isolierten Meerschweinchendarm vergleichend untersucht.
N2  - Silatiemonium iodide (16b), a sila-analogue of the anticholinergic tiemonium iodide (16a), and the siJa-analogue 14b of the corresponding free base 14a were synthesized for the first time. Compounds 14b and 16b as weil as their precursors 10-13 and 15 were characterized by their physical and chemical properties. Their structures were confirmed by elementary analyses, (^1\)H NMRand massspectroscopy. The spasmolytic properties of the pairs 14a/14b and 16a/16b were compared on the isolated guinea pig ileum.
KW  - Anorganische Chemie
Y1  - 1980
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-63669
ER  - 
TY  - JOUR
A1  - Tacke, Reinhold
A1  - Niedner, R.
A1  - Frohnecke, J.
A1  - Ernst, L.
A1  - Sheldrick, W. S.
T1  - Darstellung und Eigenschaften potentiell curarewirksamer Silicium-Verbindungen, II
T1  - Preparation and Properties of Silicon Compounds withPotential Curare-Like Activity, II
N2  - Die potentiell curarewirksamen Silicium-Verbindungen Sa, Sc, Sd, Sg, Sh und 9a-9d wurden dargestellt. \(^1\)H-NMR-spektroskopische Untersuchungen ergaben Informationen über die Konformationen von 5 a- Sc in Lösung. Die Kristall- und Molekülstruktur von 5 c wurde röntgenstrukturanalytisch bestimmt. Die muskelrelaxierenden Eigenschaften von S a- 5 h und 9 a-9 d wurden vergleichend an der Maus (i.v., LD50-Werte) untersucht. Die ermittelten Struktur-WirkungsBeziehungen werden in Hinblick auf die unterschiedlichen kovalenten Radien des Kohlenstoffund Siliciumatoms und die hieraus resultierenden N ... N-Abstände diskutiert.
N2  - 'The potential curare-like silicon compounds Sa, Sc, Sd, Sg, Sb, and 9a-9d were synthesized. \(^1\)H-NMR spectroscopic investigations provided information about the conformations of Sa-Sc in solution. The crystal and molecular structures 5 c were determined by X-ray structural analysis. The muscle relaxing properties of Sa-Sb and 9a-9d were investigated comparatively on mice (i. v., LD50 values). The observed structure-activity relationships are discussed with respect to the different covalent radii of the carbon and silicon atoms and the N ... N distances resulting therefrom.
KW  - Anorganische Chemie
Y1  - 1980
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-63670
ER  - 
TY  - JOUR
A1  - Leininger, H.
A1  - Christl, Manfred
T1  - Oxidationsreaktionen am Benzvalen: Ozonolyse, cis-Hydroxylierung, Epoxidation und Singulettsauerstoff-Addition
N2  - No abstract available
KW  - Organische Chemie
Y1  - 1980
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-58088
ER  - 
TY  - JOUR
A1  - Christl, Manfred
A1  - Lang, R.
A1  - Herbert, R.
A1  - Freitag, G.
T1  - Zusammenhang zwischen Orbitalcharakter und Reaktionsprodukt bei der Umsetzung von Benzvalen und Homobenzvalen mit Thiophenol
N2  - No abstract available
KW  - Organische Chemie
Y1  - 1980
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-58065
ER  - 
TY  - JOUR
A1  - Christl, Manfred
A1  - Lang, R.
A1  - Lechner, M.
T1  - Tetra- und pentacyclische Tricyclo[4.1.0.0\(^{2,7}\)]hept-3-en-Derivate; Abfangprodukte des Tricyclo[4.1.0.0\(^{2,7}\)]hepta-3,4-diens
N2  - No abstract available
KW  - Organische Chemie
Y1  - 1980
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-58078
ER  - 
TY  - GEN
T1  - Jahresbericht 1979
T1  - Annual Report 1979
N2  - Die Entwicklung der Universitätsbibliothek Würzburg im Jahr 1979.
N2  - Annual Report of the University Library of Würzburg, 1979.
T3  - Jahresbericht der Universitätsbibliothek Würzburg - 1979 
KW  - Würzburg
KW  - Universitätsbibliothek
KW  - Bericht
KW  - Jahresbericht
KW  - Würzburg
KW  - University Library
KW  - Report
KW  - Annual Report
KW  - Wuerzburg
KW  - Wurzburg
Y1  - 1980
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-42223
ER  - 
TY  - CHAP
A1  - Krüger, Hans-Peter
T1  - Selbst- und Fremdbeurteilung in Diagnostik und Psychotherapie
N2  - No abstract available
KW  - Klinische Psychologie
KW  - Psychotherapie
Y1  - 1980
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-40964
ER  - 
TY  - CHAP
A1  - Krüger, Hans-Peter
A1  - Kohnen, Ralph
T1  - Evaluierung gruppentherapeutischer Situationen durch physiologische Parameter und Selbsteinschätzungen
N2  - No abstract available
Y1  - 1980
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-40971
ER  - 
TY  - JOUR
A1  - Krüger, Hans-Peter
A1  - Lienert, Gustav A.
T1  - Eine exakte nonparametrische Prüfung auf Kovariation zweier autokorrelierter Zeitreihen
N2  - Häufig tritt in der psychologischen und psychiatrischen Forschung die Frage nach dem Zusammenhang zwischen zwei oder mehreren Zeitreihen auf. übliche Kovariationsmaße versagen dabei vor allem deshalb, weil sie nicht inferentiell ausgewertet werden können. An einem Beispiel aus der Pharmakopsychologie wird ein auf Pfanzagl (1963) zurückgehendes Verfahren vorgeschlagen, das es erlaubt, voraussetzungsfrei den Zusammenhang zwischen autokorrelierten Meßwertreihen zu prüfen. Als Unabhängigkeit zweier Zeitreihen wird definiert, daß zwischen ihnen bei Erhaltung der Autokorrelation kein höherer Zusammenhang besteht als nach dem Zufall zu erwarten.
N2  - The problem of examining the relation between two or more series of successive observations occurs often in the psychologieal and psychiatrie research. The usual methods of measuring covariation cannot be employed here, particularly because they cannot be used to draw inferences. The present paper describes a new method to examine the relation between autocorrelated series of successive observations, without using any presuppositions. Two successive series are considered to be independent, when the relation between them is not higher than that expected by chance. The method described here is based upon a paper by Pfanzagl (1963), and is illustrated with the help of an example from the field of Pharmacopsychology.
Y1  - 1980
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-41049
ER  - 
TY  - JOUR
A1  - Krüger, Hans-Peter
A1  - Kohnen, Ralf
A1  - Lienert, Gustav A.
T1  - Lautstärke ungleich Lautheit: Wirkung von Psychopharmaka auf das Lärmerleben
T1  - Sound Intensity unequal Loudness: Effect of Psychopharmacologic Agents on the Experience of Noise
N2  - No abstract available
Y1  - 1980
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-41026
ER  - 
TY  - JOUR
A1  - Krüger, Hans-Peter
A1  - Kohnen, Ralf
A1  - Lienert, Gustav A.
T1  - Aufgabenvariation als Aktivationsparameter in Tranqualizer-Untersuchungen
T1  - Choice of Performance Tasks as an Activation Parameter in Minor Tranquilizer Trials
N2  - No abstract available
Y1  - 1980
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-41016
ER  - 
TY  - JOUR
A1  - Burschka, Christian
A1  - Leonhard, K.
A1  - Werner, H.
T1  - Basische Metalle. XIV. Synthese und Kristallstruktur von C\(_5\)H\(_5\)(PMe\(_3\))CoS\(_5\) : Ein neuer Metallapentathia-Heterocyclus
T1  - Basic Metals. XIV. Synthesis and Crystal Structure of C\(_5\)H\(_5\)(PMe\(_3\))CoS\(_5\) : A New Metallapentathia Heterocycle
N2  - Der Zweikernkomplex C\(_5\)H\(_5\)(PMe\(_3\))Co(\(\mu\)-CO)\(_2\)Mn(CO)C\(_5\)H\(_4\)Me (8) reagiert mit stöchiometrischen Mengen S\(_8\) in praktisch quantitativer Ausbeute zu C\(_5\)H\(_5\)(PMe\(_3\))CoS\(_5\) (4). Der Koba.ltapentathia-Heterocyclus 4 ist ebenfalls aus C\(_5\)H\(_5\)(PMe\(_3\))Co(h\(^2\)-CS\(_2\)) (5) und S\(_8\) zugänglich. 4 kristallisiert monoklin mit den Gitterkonstanten a = 8,467(3) A, b = 12,128(4) A, c = 14,210(4) A und \(\beta\) = 102,20(2)°_ Die Sesselform des sechsgliedrigen CoS\(_5\)-Rings entspricht derjenigen in den bekannten Verbindungen (C\(_5\)H\(_5\))\(_2\)TiS\(_5\) und (C\(_5\)H\(_5\))\(_2\)VS\(_5\) , wobei in 4 der Cyclopentadienylligand die axiale und die Trimethylphosphingruppe die ä.quatoriale Position einnehmen.
N2  - The dinuclear complex C\(_5\)H\(_5\)(PMe\(_3\))Co(\(\mu\)-CO)\(_2\)Mn(CO)C\(_5\)H\(_4\)Me (8) reaots with stoichiometric amounts of S\(_8\) to form C\(_5\)H\(_5\)(PMe\(_3\))CoS\(_5\) (4) in practica.lly quantitative yields. The cobalt. apentathia heterocycle 4 is a.lso obtained by the reaction of C\(_5\)H\(_5\)(PMe\(_3\))Co(h\(^2\)-CS\(_2\)) (5) with S\(_8\), Cry. stals of 4 are monoclinic with a = 8.467(3) A, b = 12.128(4) A, c = 14.210(4) A and \(\beta\) = 102.20(2)°. The chair form of the six·membered CoS\(_5\) ringcorresponds to that of the compounds (C\(_5\)H\(_5\))\(_2\)TiS\(_5\) and (C\(_5\)H\(_5\))\(_2\)VS\(_5\) In 4, the cyclopentadienyl ligand occupies the axial and the trimethylphosphine group the equatorial position.
KW  - Chemie
Y1  - 1980
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-31407
ER  - 
TY  - JOUR
A1  - Burschka, Christian
T1  - CsCu\(_4\)S\(_3\) und CsCu\(_3\)S\(_2\) : Sulfide mit tetraedrisch und linear koordiniertem Kupfer
T1  - CsCu\(_4\)S\(_3\) and CsCu\(_3\)S\(_2\): Sulfides with Copper in Tetrahedral and Linear Coordination
N2  - No abstract available
KW  - Chemie
Y1  - 1980
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-31366
ER  - 
TY  - JOUR
A1  - Scheer, Ulrich
A1  - Sommerville, John
A1  - Müller, Ulrike
T1  - DNA is assembled into globular supranucleosomal chromatin structures by nuclear contents of amphibian oocytes
N2  - The assembly of DNA into nucleosomal and supranucleosomal chromatin structures has been studied (i) by injection of circular DNA molecules (plasmids) into nuclei of Pleurodeles waltlii oocytes; and (ii) by in vitro incubation of plasmid molecules with the supernatant fraction from oocyte nuclei of Pleurodeles and Xenopus laevis, followed by purification of nucleoprotein structures formed with sucrose gradient centrifugation. [n both types of experiments , spread preparations of the newly assembled and transcriptionally inactive chromatin , examined by electron microscopy , show dense globular higher order (supranucleosomal) packing forms. Under partially relaxing (low salt) preparation conditions granular chromatin subunits of about 30 nm diameter can be seen either as widely spaced particles or in closely packed aggregates. The transcriptionally inactive endogenous chromatin of chromomeres of lampbrush chromosomes is arranged in similar higher order chromatin units. A correlation is found between the sizes of the DN A molecule probes used and the numbers of nucleosomes and higher order globules in the assembled chromatin structures. After prolonged dispersion in low salt buffers , these globular chromatin units unfold into chains of7-12 nucleosomes. The results support the concept that chromatin is arranged , under physiological ion concentrations as they are present in the nucleus , in supranucleosomal units of globular morphology.
Y1  - 1980
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-39671
ER  - 
TY  - CHAP
A1  - Wilhelm, Gernot
T1  - Die Fortsetzungstafel eines Briefes aus Kamid el-Loz (KL 72 : 600)
N2  - No abstract available
KW  - Archäologie
KW  - Bronzezeit
KW  - Tempel
KW  - Ausgrabungen
Y1  - 1980
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-78079
ER  - 
TY  - CHAP
A1  - Wilhelm, Gernot
T1  - Ein Gefäßfragment mit alphabetischer Keilinschrift
N2  - No abstract available
KW  - Archäologie
KW  - Bronzezeit
KW  - Ausgrabungen
KW  - Tempel
KW  - Funde
Y1  - 1980
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-78068
ER  - 
TY  - JOUR
A1  - Schneider, Wolfgang
T1  - Kausalmodelle in der Pädagogischen Psychologie - Ergänzende Analysen zu zwei einschlägigen Untersuchungen
N2  - In the present secondary analysis the results of studies by Simons et al. (1975) and Schwarzer (1979) were critically reanalyzed. The central point of the reanalysis concerned the test of the causal models used, especially the question, if the technique of path analysis was correctly applied. Whereas some modifications seemed necessary in both srudies, there was no reason to question their main results.
KW  - Pädagogische Psychologie
KW  - Kausalmodell
Y1  - 1980
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-87249
ER  - 
TY  - JOUR
A1  - Tacke, Reinhold
A1  - Bentlagem, A.
A1  - Towart, R.
A1  - Meyer, H.
A1  - Bossert, F.
A1  - Vater, W.
A1  - Stoepe, K.
T1  - Sila-Analoga von Nifedipin-ähnlichen 4-Aryl-2.6-dimethyl-1.4-dihydropyridin-3.5-dicarbonsäure-dialkylestern, I
N2  - no abstract available
KW  - Chemie
Y1  - 1980
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-82430
ER  - 
TY  - JOUR
A1  - Wilhelm, Gernot
T1  - Der Komitativ des Urartäischen
N2  - No abstract available
KW  - Minoische Kultur
KW  - Mykenische Kultur
KW  - Ägäische Kultur
KW  - Anatolische Sprachen
Y1  - 1980
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-82771
ER  - 
TY  - BOOK
A1  - Wolf, Norbert Richard
A1  - Domröse, Gerd
A1  - Liebel, Hermann
T1  - List Sprachbuch 5
N2  - No abstract available
KW  - Deutschunterricht
KW  - Lehrmittel
Y1  - 1980
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-41637
ER  - 
TY  - CHAP
A1  - Franke, Werner W.
A1  - Scheer, Ulrich
A1  - Zentgraf, Hanswalter
A1  - Trendelenburg, Michael F.
A1  - Müller, U.
A1  - Krohne, G.
A1  - Spring, H.
T1  - Organization of transcribed and nontranscribed chromatin
N2  - No abstract available
KW  - Tumor / Zellteilung
Y1  - 1980
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-40656
ER  - 
TY  - JOUR
A1  - Scheer, Ulrich
T1  - Structural organization of spacer chromatin between transcribed ribosomal RNA genes in amphibian oocytes
N2  - Transcribed nucleolar chomatin, including the spacer regions interspersed between the rRNA genes, is different from the bulk of nontranscribed chromatin in that the DNA of these regions appears to be in an extended (B) conformation when examined by electron microscopy. The possibility that this may reflect artificial unfolding of nucleosomes during incubation in very low salt buffers as routinely used in such spread preparations has been examined by studying the influence of various ion concentrations on nucleolar chromatin structure. Amplified nucleolar chromatin of amphibian oocytes (Xenopus laevis, Pleurodeles waltlii, Triturus cristatus) was spread in various concentrations of NaCl (range 0 to 20 mM). Below 1 mM salt spacer chromatin frequently revealed a variable number of irregularly shaped beads, whereas above this concentration the chromatin axis appeared uniformly smooth. At all salt concentrations studied, however, the length distribution of spacer and gene regions was identical. Preparations fixed with glutaraldehyde instead of formaldehyde, or unftxed preparations, were indistinguishable in this respect. The observations indicate that (i) rDNA spacer regions are not compacted into nucleosomal particles and into supranucleosomal structures when visualized at chromatin stabilizing salt concentrations (e.g., 20 mM NaCl), and (ii) spacer DNA is covered by a uniform layer of proteins of unknown nature which, at very low salt concentrations (below 1 mM NaCl), can artificially give rise to the appearance of small granular particles of approximately nucleosome-like sizes. These particles, however, are different from nucleosomes in that they do not foreshorten the associated spacer DNA. The data support the concept of an altered nucleohistone conformation not only in transcribed chromatin but also in the vicinity of transcriptional events.
KW  - Cytologie
KW  - Chromatin structure
KW  - rDNA
KW  - amphibian oocytes
Y1  - 1980
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-41057
ER  - 
TY  - JOUR
A1  - von Jagow, Gerhard
A1  - Sebald, Walter
T1  - b-Type cytochromes
N2  - No abstract available
KW  - Biochemie
Y1  - 1980
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-47383
ER  - 
TY  - JOUR
A1  - Sebald, Walter
A1  - Machleidt, Werner
A1  - Wachter, Elmar
T1  - N,N'-dicyclohexylcarbodiimide binds specifically to a single glutamyl residue of the proteolipid subunit of the mitochondrial adenosinetriphosphatases from Neurospora crassa and Saccharomyces cerevisiae
N2  - T~e N,N'-dicrclohexylcarbodiimide-binding proteolipid subumt of the mitochondrial adenosinetriphosphatases (ATP phosphohydrolase, EC 3.6.1.3) of Neurosporacrassa and Saccharomyces cerevisiae were purified from mitochondria incubated with the radioactively labeled inhibitor. The specifically labeled subunit was cleaved with cyanogen bromide and N-bromosuccinimide, and the resultant fragments were separated by gel chromatography in the presence of 80% (vol/vol) formic acid. The N,N'-dicyclohexylcarbodiimide label was recovered in each organism exclusively in a 17-residue fragment. Further analysis by automated solid-phase Edman degrada.ti.on revealed tha~ the bound label was present at only one positIOn, correspondmg to a glutamyl residue. The NN'~ icyc~ohexyl~a~bodiiJ?1~de-'!l0dified glutamyl residue is the ~nly Id~ntIcal aCidic posItIon m both proteins and occurs in the middle of a hydrophobic sequence of about 25 residues.
KW  - Dicyclohexylcarbodiimid
KW  - Aminosäuren
KW  - inhibition of H+ translocation
KW  - amino acid sequence
KW  - automated solid-phase Edman degradation
Y1  - 1980
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-47394
ER  - 
TY  - BOOK
A1  - Koller, Erwin
T1  - Totentanz: Versuch einer Textembeschreibung
N2  - No abstract available
KW  - Deutsch
KW  - Totentanz
KW  - Literatur
KW  - Textsorte
Y1  - 1980
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-47239
SN  - 3-85124-077-4
N1  - Zugl. Innsbruck, Univ., Habilitationsschrift, 1980
ER  - 
TY  - BOOK
A1  - Bach, Ulrich
A1  - Wolff, Dieter
T1  - Ausgewählte Bibliographie zur Psycholinguistik und Sprachpsychologie
N2  - No abstract available
KW  - Psycholinguistik
KW  - Bibliographie
Y1  - 1980
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-47220
SN  - 3-589-20757-4
ER  - 
TY  - CHAP
A1  - Weinert, Franz E.
A1  - Schneider, Wolfgang
A1  - Treiber, Bernhard
T1  - Bedingungsanalysen von (erwartungswidrigen) Schulleistungen
N2  - No abstract available.
KW  - Schulleistung
KW  - Fähigkeit
KW  - Leistungsmotivation
KW  - Erwartungwidrigkeit
Y1  - 1980
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-87261
ER  - 
TY  - JOUR
A1  - Treiber, Bernhard
A1  - Schneider, Wolfgang
T1  - Qualifizierende und varianzreduzierende Wirkungen von Schulklassenunterricht
N2  - Schulklassenunterricht soll möglichst vielen Schülern ein möglichst hohes kognitives Leistungsniveau erreichen helfen. Nur wenige Unterrichtsstudien haben bisher jedoch zur Aufklärung jener Lehr-Lern-Bedingungen beigerragen, unter denen sich hohe qualifikatorische und varianzreduktive Wirkungen gleichzeitig erreichen lassen. Die vorliegende Studie greift dafür auf Merkmale einer adaptiv-remedialen Lehr-Lern-Organisation zurück und überprüft ihren Erklärungsgehalt im Mathematikunterricht von 58 fünften Hauptschulklassen. Zur systematischen Entwicklung komplexer Erklärungen und ihrer einzelfallartigen Beurteilung wird ein neu entwickeltes Programmsystem (HYPAG) angewandt. Es fühn zur Auswahl einer Annahmenstruktur, in der Instrumental- und Rahmenbedingungen von Schulklassenunterricht in Wechselwirkung stehen, für sich genommen aber nur mehr hinreichende und darin substiruierbare Bedingungen qualifizierender und varianzreduktiver Unterrichtseffekte sind.
KW  - Schulklasse
KW  - Unterricht
KW  - Wirkung
Y1  - 1980
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-87259
ER  - 
TY  - CHAP
A1  - Hommers, Wilfried
T1  - Recht und Psychologie - Ein wechselseitiges Verhältnis
T1  - Juristic thought and psychology: A relation of interdependence
N2  - Traditionally psychological research had assisted (de lege lata and de lege ferenda) jurisdiction, legislation, and law enforcement. However, the fol1owing three examp1es support the thesis that certain areas of psycho1ogica1 research gain new concepts and hypotheses by considering re1ated juristic thought. First, a developmenta1 study on the judgment about neg1igent damages suggested a three-step deve10pment of the evaluation of neg1igence. That threestep development wou1d contradict Heider's sequence of responsibi1ity levels. Second, a cognitive algebra approach to asses the chi1d's understanding of the duty to compensate the victim for his 1055 caused by a culpab1e actor suggested a two-step deve10pment of understanding that duty. The chi1d of the first deve10pment a1 step wou1d regard giving on1y half compensation of the 10ss as doing his duty to repair damages. Third, the concept of cul pa and the "Strafzumes sungs 1 ehre" in the German juri 5 ti c thought are d i scussed as key concepts for innovating psycho1ogica1 research on a moral algebra. Insofar juristic thought proved to assist psycho1ogica1 theory bui1ding what would make the relation of juristic thought and psycho1ogy a relation of interdependence.
Y1  - 1980
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-43938
ER  - 
TY  - CHAP
A1  - Krüger, Hans-Peter
A1  - Wolfrum, Christine
T1  - Die Homogenität von Interaktion als Skalierungskriterium
N2  - No abstract available
Y1  - 1980
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-41288
ER  - 
TY  - JOUR
A1  - Krüger, Hans-Peter
A1  - Kohnen, Ralf
T1  - Eine neue Methode zur Prüfung der Wirkung von Psychopharmaka - Die "Weltbeschreibung"
N2  - Kompensation und das Problem der Zuggebbarkeit werden als die beiden wichtigsten Störquellen bei der Erfassung pharmakonbedingter Befindlichkeitsänderungen dargestellt. Gefördert werden diese Prozesse durch eine Zentrierung der Methode auf die Selbstbeobachtung. Es wird die Hypothese aufgestellt, daß die Selbstbeobachtung ersetzbar ist durch eine Beschreibung der "Welt draußen". Die Person kann sich nur in der Welt erleben - folglich werden Veränderungen dieses Erlebnis auch Veränderungen in der Beschreibung der Welt nach sich ziehen. Ausgehend von dieser Hypothese wird ein Experiment konzipiert, in dem die Vpn lediglich die experimentelle Situation und die am Experiment beteiligten anderen Vpn beschreiben, nicht aber sich selbst. Es kann gezeigt werden, daß mit den so gewonnenen Maßen eindeutige Wirkungen des eingesetzten Tranquilizers nachgewiesen werden können, ebenso eindeutige Dosis-Wirkungs-Beziehungen. Die Konsequenzen für eine pharmakopsychologische Methodik werden diskutiert. Zudem wird herausgehoben, daß Tranquilantien dann als positiv bewertet werden können, wenn sie die Reagibilität der Vpn auf die Situation erhöhen und durch eine Verringerung des allgemeinen Aktivierungsniveaus eine adäquate Verarbeitung angstinduzierender Situatonen ermöglichen.
N2  - Compensation and readiness to admit drug effects are described as the most important modifying factors in assessing changes of mood that is due to psychotropic drugs. Both processes are advanced by a methodology which focuses on the selfobservation of the experimental subjects. The authors propose the hypothesis that seifreports may be replaced by a description of the "outside world". The human being is only able to experience itself within its concrete world; consequently, changes of its experience entail changes of the description of the world. On the basis of this hypothesis an experiment is conceived in which the subjects describe only the experimental situation and the other participating subjects, not themselves, however. The authors hold that the parameters emerging from this approach give evidence both of clear-cut tranquilizer-effects and stable drug-dosage-relationships. Consequences for pharmaco-psychological methodology are discussed. The authors accentuate that tranquilizers can be seen as having positive effects if they help to enhance the subject's reagibility to the situation and, by reducing the general activation level, enable the subject to cope with anxiety inducing situations.
Y1  - 1980
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-41566
ER  - 
TY  - JOUR
A1  - Krüger, Hans-Peter
A1  - Buchta, Herbert
T1  - Nichtparametrischer Vergleich von Testprofilen und Verlaufskurven bei unabhängigen Stichproben
N2  - Werden k Testwerte an zwei oder mehreren Stichproben von Pbn erhoben, stellt sich das Problem des Vergleichs von Testprofilen. Ähnliche Fragen treten auf, wenn statt k verschiedenen Testwerten ein Meßwert zu k Zeitpunkten an einem Pb erhoben wird. Zur Auswertung dieser Fragestellung wird ein Vorgehen nach dem WILCOXON-Rangsummentest vorgeschlagen, der es erlaubt (1) Unterschiede aller Art (2) Unterschiede in der Lage und (3) Unterschiede in der Form der Profile zu prüfen. Das Vorgehen wird an einem Beispiel aufgezeigt. Erweiterungen auf andere Fälle werden diskutiert.
N2  - If kotest scores are collected in two or more sampies of subjects the problem of a comparison of test-proftles arises. Similar problems can be observed in those cases in which instead of k-different test-scores a test result of k-times is ascertained from a subjecL For purposes of interpretation an approach (Wi1coxon rank sum test) is suggested allowing the examination 01 1) differences of all kind, 2) differences of location and 3) differences of the forms of profIles. This approach is demonstrated by means of an example. Possibilities of applieating this approach in other eases are discussed.
Y1  - 1980
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-41513
ER  - 
TY  - JOUR
A1  - Krüger, Hans-Peter
T1  - Grundlagen und Probleme von Dimensionen in der Psychologie / Heinrich Wottawa
N2  - Buchbesprechung von Grundlagen und Probleme von Dimensionen in der Psychologie / Heinrich Wottawa. - Meisenheim am Glan: Hain, 1979. - 122 S., ISBN: 3-445-01927-4. - (Psychologia universalis ; 40)
KW  - Dimension
KW  - Psychologie
KW  - Skalierung
KW  - Testtheorie
KW  - Faktorenanalyse
KW  - Rezension
Y1  - 1980
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-41546
ER  - 
TY  - JOUR
A1  - Daut, Volker
T1  - Die Entwicklung der Todesvorstellung bei Kindern und Jugendlichen
N2  - No abstract available
Y1  - 1980
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-36069
ER  - 
TY  - CHAP
A1  - Clarke, AH
A1  - Ellgring, Johann Heinrich
A1  - Wagner, H.
T1  - Situational effects on the syntax of speech and gaze behaviour in dyads
N2  - A substantial literature exists on the coordination of speaking and looking behaviour and their significance as indicators for the production and reception of social information. Within this framework, the temporal organisation of such behaviour has been 'shown to reflect both the coordination within the individual and between participants in a situation. In this paper, it is proposed that observed behavioural sequences may be formally described by rules of syntax, thus implying the likelihood of structural organisation as opposed to, for example, linear time dependence between behavioural states. This being the case, differing sets of rules and grammars respectively can be expected for various social situations. Clinical interviews and discu~sions between couples on a topic of marital conflict were analysed, the on-off patterns of speech and gaze being taken as data. The resulting behavioural repertoire was regarded, in the sense of a formal grammar, as the terminal vocabulary. A set of rewriting rules was determined and their associated probabilities inferred. The situational conditions were found to be reflectedin the syntactic features of the grammatical model - the terminal vocabulary, the production rules and the production probabilities.
KW  - Psychologie
KW  - Social interaction
KW  - verbal and nonverbal communication
KW  - mathematical linguistics
KW  - grammar
KW  - rules of syntax
KW  - behavioural analysis
Y1  - 1980
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-50316
ER  - 
TY  - CHAP
A1  - Krüger, Hans-Peter
A1  - Rausche, A.
T1  - Die Prüfung von Verlaufskurven auf das Vorliegen von Trends über die exakte Verteilung von Spearman's S
N2  - no abstract available
KW  - Psychologie
Y1  - 1980
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-79827
ER  - 
TY  - JOUR
A1  - Krüger, Hans-Peter
A1  - Kohnen, Ralf
T1  - Wirkungen von Psychopharmaka auf das Lärmerleben
N2  - In allgemeinpsychologischen Lärmexperimenten ist eine monotone Beziehung zwischen physikalischer Lautstärke und erlebter Lautheit bestens abgesichert. In der vorliegenden Arbeit wird gezeigt, daß diese Beziehung unter Medikationsbedingungen nicht gilt. In einem 3 X 3 X 2-faktoriellen Versuchsplan mit den Faktoren physikalische Lautstärke (weißes Rauschen in 76, 79 und 82 dB), Medikation (Tranquilizer, Plazebo, Stimulizer) und (niedere bzw. hohe) Ansprechbarkeit auf Medikamente beurteilten insgesamt 54 junge weibliche Versuchspersonen in sechs Durchgängen eine Serie von 12 gleichabständigen Lärmstufen von 58 bis 92 dB in bezug auf die erlebte Lautheit. Es war weder eine Hauptwirkung Physikalische Lautstärke noch Medikation aufgetreten, dafür differenzierte die Schichtungsvariable Ansprechbarkeit auf beiden Faktoren. Eine Interpretation der Ergebnisse sensu Eysencks Drogenpostulat und im Sinne einer Aktivierungstheorie wird vorgenommen. Als Konsequenz für pharmakopsychologisches Experimentieren wird die Forderung erhoben, die in das Experiment eingebrachten Unabhängigen Variablen in ihrer Wirkung auf das Erleben der Vpn zu kontrollieren (subjektive Repräsentation des experimentellen Angebotes).
N2  - 54 young female subjects were required to report the experienced loudness of aseries of 12 white noises of 58 to 92 db, after having taken a tranquillizer, a placebo, or a stimulant, in a room with a white noise of 76, 79, or 82 db, respectively. The subjects were divided into two groups according to their sensitivity to drugs. The subjects being sensitive to drugs, expeiienced the loudness of the whole series of white noises, after having taken the tranquillizer, or in the room with a white noise of 76 or 79 db, respectively, as "high", and after having taken the stimulant, or in the room with a white noise of 82 db, as "low". On the contrary, the subjects being not sensitive to drugs, experienced the loudness of the whole series of white noises, after having taken the stimulant, or in the room with a white noise of 82 db, as "high", and after having taken the tranquillizer, or in the room with a white noise of 76 or 79 db, respectively, as "low". The results were discussed in the light of Eysenck's theory of drugeffects and of an activation theory. The results show the necessity of controlling the experienced intensity of loudness in pharmaco-psychological experiments.
Y1  - 1980
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-41305
SN  - 0044-2712
ER  - 
TY  - JOUR
A1  - Ellgring, Johann Heinrich
A1  - Wagner, Helmut
A1  - Clarke, Andrew H.
T1  - Binäre Kodierung von Sprechen und Blicken: Validität, Reliabilität und ihre Abhängigkeit von der zeitlichen Auflösung
N2  - Validität und Reliabilität der Sprechkodierung einer Beobachtergruppe wurden in Abhängigkeit von der zeitlichen Auflösung untersucht. Die Validität wurde anhand der Übereinstimmung der Beobachter mit einem automatischen Sprachdetektor berechnet. Die Reliabilitätswerte für die Kodierung von Sprechen und Blikken ergaben sich aus der Übereinstimmung der Beobachter untereinander. Im wesentlichen zeigten sich folgende Ergebnisse: 1. Die Validität/Reliabilität der Sprechkodierung ist eine monotone, nichtlineare Funktion der gewählten Auflösung. Die systematischen Fehler, die auf Latenz und Trägheit der menschlichen Beobachter zurückgehen, werden bei einer Auflösung von 400 msec nahezu vollständig unterdrückt. 2. Weder bei der Erfassung des Sprech- noch des Blickverhaltens lassen sich Anzeichen für Observer-Drift feststellen. Trainierte und untrainierte Beobachter unterscheiden sich nicht signifikant. 3. Die Kodierung des Sprechverhaltens ist geringfügig reliabler als die des Blickverhaltens. Dieser Unterschied kann in der Praxis vernachlässigt werden.
N2  - The reliability of the binary coding of speech and gaze was examined as a function of the temporal resolution of measurement. The reliability was calculated as the agreement between human observers. In addition, the validity of the speech coding could be determined from the agreement between the human observers and an electronic speech detector.
Y1  - 1980
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-43163
ER  - 
TY  - BOOK
A1  - Schneider, Wolfgang
T1  - Bedingungsanalysen des Rechtschreibens
N2  - No abstract available.
KW  - Rechtschreibung
KW  - Leistungsdiagnostik
KW  - Kreativität
KW  - Legasthenie
KW  - Forschung
KW  - Schulleistung
KW  - Informationsverarbeitung
KW  - Theorie
Y1  - 1980
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-87151
ER  - 
TY  - CHAP
A1  - Ellgring, Johann Heinrich
T1  - Video in der Verhaltenstherapie
N2  - No abstract available
Y1  - 1980
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-42048
ER  - 
TY  - CHAP
A1  - Ellgring, Johann Heinrich
A1  - Wagner, H.
A1  - Clarke, AH
T1  - Psychopathological states and their effects on speech and gaze behaviour
N2  - Internal characteristics such as depressed mood, anxiety and general negative emotions are accompanied, particularly during depressive illness, by changes in observable behaviour. Accordingly, the following questions may be examined: are intra-individual changes in speech and gaze behaviour related to changes in the internal psychopathological state? Further, do these changes occur synchronously to changes in the state of subjective well-being? A longitudinal study was made on depressed patients. Their behaviour was observed during standardised interviews and diagnostic-therapeutic discussions held at regu~ lar intervals. Various speech and gaze parameters were examined with respect to their coordination and their relationship to the subjective state of well-being. Considerable variation was found in the temporal relationship amongst these variables. The results are discussed with respect to the relevance of speech parameters and the coordination of verbal and nonverbal behaviour as indicators of the psychopathological condition.
KW  - Psychologie
KW  - Social interaction
KW  - depression
KW  - verbal and nonverbal behaviour
KW  - speech
KW  - looking behaviour
KW  - dyadic interaction
KW  - single case study
Y1  - 1980
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-50323
ER  - 
TY  - CHAP
A1  - Ruhe, Ernstpeter
T1  - Vorwort zu "De l´art de parler"
N2  - No abstract available
KW  - Bernard Lamy
KW  - Reden
Y1  - 1980
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-36784
ER  - 
TY  - JOUR
A1  - Burschka, Christian
A1  - Stroppel, Klaus
A1  - Jutzi, Peter
T1  - Die Struktur von μ-Dibromgermandiyl-bis(pentacarbonylwolfram)(W-W)
N2  - No abstract available
KW  - Chemie
Y1  - 1981
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-31852
ER  - 
TY  - JOUR
A1  - Sirén, Anna-Leena
T1  - Central cardiovascular and thermal effects of prostacyclin in rats
N2  - Prostacyclin (PGI2) induced a dose-dependent decrease in blood pressure with slight increases in heart rate and body temperature, when administered at the doses of 0.1-100 ~g into the lateral cerebral ventricle (i.c.v.) of the urethane-anaesthetised rat. When the same doses were administered intravenously, both the blood pressure and heart rate decreased. Central pretreatment wib~ sodiurn meclofenamate (1 mg/rat i.c.v.) antagonised the central hypotensive effect of PGI2 but i.c.v. pretreatrnent of the rats with indomethacin (1 mg/rat) failed to affect the PGI 2-induced hypotension. Central pretreatment with two histamine H2-receptor antagonists, cimetidine (500 ~g/rat i.c.v.) or metiamide (488 ~g/rat i.c.v.), antagonised the blood pressure lowering effect of 0.1 ~g dose of PGI2 but failed to affect the hypotension induced by higher PGI2 doses. Therefore the main central hypotensive effect of PGI2 seems not to be associated with the stimulation of histamine H2 -receptors in the brain. The hypotensive effect of i.c.v. administered PGI2 appears to be due to an action upon the central nervous system rather than to a leakage into the peripheral circulation. This assurnption is supported by the fact that sodiurn meclofenamate i.c.v. antagonised the effect of PGI 2. In addition, the chronotropic response to i.c.v. PGI2 was opposite to that induced by intravenous administration. The results also suggest that there may be differences in the mode of action between sodiurn meclofenamate and indomethacin.
KW  - Prostaglandine
Y1  - 1981
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-47943
ER  - 
TY  - JOUR
A1  - Jutzi, Peter
A1  - Karl, Alfons
A1  - Burschka, Christian
T1  - Synthese, Reaktionen und Struktur von Tricarbonyl(1R,1R',2,3,4,5-Tetraphenyl-1-Germacyclopentadien) Eisen-Komplexen
N2  - Die Tricarbonyl(germacy~lopentadien)eisen-Komplexe VI-X werden durch Umsetzung der Germacyclopentadiene I-V niit Fe(CO)\(_5\) dargestellt. In l,l-Dialkyl- und -Diaryl-l-gemiacyclopentadien-Komplexen kann die Ge-C( exo )-Bindung durch verschiedene Elementhaloge~de gespalten werden, wobei die I-Halogen-l-germacyclopentadien-Komplexe XII, XIII, XV-XVII gebildet werden. Eine Entkomplexierung des Komplexes XI tritt bei der Reaktion mit Me\(_3\)NO oder TiCl\(_4\) ein. Das Tricarbonyl(l-chlor-l-germacyclopentadien)eisen XII reagiert mit AgF, NaJ, NaOMe und LiAIH\(_4\) zu den Komplexen XIXXXII. Das German XXII kann mit CCl\(_4)\ in XII überführt werden. Die Tricarbonyleisen-Komplexe XI, XII, XVI, XVII und XIX reagieren photochemisch mit Trimethylphosphan zu den Dicarbonyl(trimethylphosphan)-Komplexen XXIII-XXVII. Die Kristallstruktur des Tricarbonyl(l-exo-fluor-1-endo-methyl-2,3,4,5-tetraphenyl-1-germacyclopentadien)eisen wird beschrieben.
N2  - The tricarbonyl(germacyclopentadiene)iron complexes VI-X are synthesized by the reaction of the germacyclopentadienes I-V with Fe(CO)\(_5\). In l,l-dialkyl- and -diaryi-l-germacyclopentadiene complexes the Ge-C(exo) bond can be split by different element halides, whereby the I-halo-l-germacyclopentadiene complexes XII. XIII. XV-XVII are formed. Decomplexation takes place by the reaction of complex XI with Me\(_3\)NO or TiCl\(_4\). Tricarbonyl(l-chloro-1-germacyclopentadiene)iron (XII) reacts with AgF. NaI. NaOMe and LiAIH\(_4\) to the complexes XIX-XXII. The germane XXII can be transferred to XII with CCl\(_4)\. The tricarbonyliron complexes XI. XII. XVI. XVII and XIX react photochemicaIly with trimethylphosphane to the dicarbonyl(trimethylphosphane) complexes XXIII-XXVll. The crystal structure of tricarbonyl(1-exo-fluoro-l-endo-methyl-2,3,4,5-tetraphenyl-l-germacyclopentadiene) iron is described.
KW  - Chemie
Y1  - 1981
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-46723
ER  - 
TY  - JOUR
A1  - Wilhelm, Gernot
T1  - Die Siegel des Königs Itḫi-teššup von Arrapḫa
N2  - No abstract available
KW  - Orientalistik
Y1  - 1981
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-51174
ER  - 
TY  - JOUR
A1  - Deltz, E.
A1  - Müller-Hermelink, HK
A1  - Ulrichs, Karin
A1  - Thiede, A.
A1  - Müller-Ruchholtz, W.
T1  - Development of graft-versus-host reaction in various target organs after small intestine transplantation
N2  - The GVHRIL foHowing transplantation of small intestine are different from those found after bone marrow transplantation or spleen cell injections in that they show a remarka ble, significant prevalence of lesions within the intestinal mucosa. These findings are consistent with the observation that jntestinal lymphocytes newly formed in mesenteric lymph nodes predominantly home in on the intestine again.& The degree of histologic alteration within different tissues indicates that the graft and the host may survive the lesions of the lymphatic tissues, whereas the severe intestinal lesions following GVHR may easily cause death of the recipient. With regard to clinical sman bowel transplantation two statements can be made: (l) GVHRIL play a significant role in small bowel trans~ plantation. (2) To minimize their biologic importance, a selective elimination of the graft's Jymph nodes by irradiation or surgical resection should be considered in view of the remarkable difference between GVHRIL in lymph nodes and in the graft's intestinal wall itself.
KW  - Chirurgie
Y1  - 1981
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-45459
ER  - 
TY  - JOUR
A1  - Däniken, A. von
A1  - Friederich, U.
A1  - Lutz, Werner K.
A1  - Schlatter, C.
T1  - Tests for mutagenicity in Salmonella and covalent binding to DNA and protein in the rat of the riot control agent o-chlorobenzylidene malononitrile (CS)
N2  - The aim of this study was to determine whether o-chlorobenzylidene malononitrile ( CS) exhibits any genotoxic activity towards Salmonella or mammalian DNA in vivo. CS was synthesized with a [\(^{14}\)C]-label at the benzylic carbon atom. It was administered i. p. at a dose level of 13 mg/kg (1 mCi/kg) to young adult male rats. Liverand kidney DNA was isolated after 8, 25, and 75 h. The radioactivity was at (liver, 8 and 75 h) or below (all other samples) the limit of detection of 3 dpm. Therefore, a possible binding of CS to DNA is at least 10\(^5\) times lower than that of the strong hepatocarcinogen aflatoxin B1, and 4,000 times lower than that of vinyl chloride. In contrast to this lack of DNA binding, but in agreement with the chemical reactivity of CS, a binding to nuclear proteins could be detected with specific activities ranging between 50 and 121 dpm/mg for liver and between 3 and 41 dpm/mg for kidney. Protein binding could well be responsible for its pronounced cytotoxic effects. Cs was also tested in the Ames Salmonella/microsome assay. Strains TA 1535, TA 1537, TA 1538, TA 98, and TA 100 were used with or without pre-incubation. Only with strain TA 100 and only without pre-incubation, a doubling of the number of revertants was detectable at the highest dose Ievels used, 1,000 and 2,000 !lg CS per plate. With pre-incubation of TA 100 with CS, a slight increase of the number of revertants was seen at 100 and 500 !lg per plate, and a subsequent fall below control values at 1,000 J.tg. A check for the number of surviving bacteria revealed a strong bacteriotoxicity of the higher doses of es so that the calculated mutation frequencies, i.e., the oumber of revertants per number of surviving bacteria, increased with doses up to 500 !J.g. This toxicity could be counteracted in part by the addition of increasing amounts of rat liver microsomes. In the view of these results, and taking into account the rare and low exposure of man, it is concluded that CS will not create a risk for the induction of point mutations or of carcinogenic processes mediated by DNA binding.
KW  - Toxikologie
KW  - o-Chlorobenzylidene malononitrile
KW  - Riot control agents
KW  - DNA Binding
KW  - Salmonella/microsome assay
KW  - Carcinogens
KW  - Mutagens
Y1  - 1981
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-61073
ER  - 
TY  - JOUR
A1  - Däniken, A. von
A1  - Lutz, Werner K.
A1  - Schlatter, C.
T1  - Lack of covalent binding to rat liver DNA of the hypolipidemic drugs clofibrate and fenofibrate
N2  - \(^{14}\)C-Labelled clofibric acid and fenofibric acid were administered p.o. to 200 g male and female rats. After 10 h, liver nuclear DNA and protein were isolated and the radioactivity was determined. Binding to protein was clearly measurable whereas no binding to DNA could be detected from any drug. A comparison of the Iimit of detection of such DNA binding with well-known chemical carcinogens revealed that the known hepatocarcinogenicity of clofibrate cannot be based upon an initiating, DNA damaging, mode of action but must be due to other, nongenotoxic, mechanisms such as peroxisome proliferation, hepatomegaly, or cytotoxicity due to protein binding. The risk assessment in man and the interpretation of the carcinogenicity data for rodents are discussed.
KW  - Toxikologie
Y1  - 1981
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-61087
ER  - 
TY  - JOUR
A1  - Tacke, Reinhold
A1  - Strecker, M.
A1  - Niedner, R.
T1  - Cholinesterase-hemmende Organophosphorsäureester und ihre Sila-Analoga
T1  - Organophosphates with Anticholinesterase Activity and their Sila-Analogues
N2  - Die Organophosphorsäureester la-4a und ihre Sila-Analoga lb-4b des Typs R\(^1\)R\(^2\)P(O)( p-OC\(_6\)H\(_4\)ElMe\(_3\)) (EI = C, Si) wurden synthetisiert. Die Kohlenstoff-Verbindungen 1 a- 4a zeigen hinsichtlich ihrer Anticholinesterase-Aktivität die gleichen Struktur-Wirkungs-Beziehungen wie die Silicium-Verbindungen 1 b- 4 b. Letztere sind jeweils wirksamer als die entsprechenden C-Analoga.
N2  - The organophosphates la-4a and their sila-analogues lb-4b of the type R\(^1\)R\(^2\)P(O)( p-OC\(_6\)H\(_4\)ElMe\(_3\) (El = C, Si) were synthesized. With regard to their anticholinesterase activity, the carbon compounds ta- 4a exhibit the same structure-activity relationships as the silicon compounds 1 b- 4b. The latter are more activ than the corresponding C-analogues.
KW  - Anorganische Chemie
Y1  - 1981
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-63689
ER  - 
TY  - JOUR
A1  - Wiese, D.
A1  - Tacke, Reinhold
A1  - Wannagat, U.
T1  - 9,9-Dimethyl-10-(3-dimethylaminopropyl)-9-silaacridan, ein Sila-Analogon des Dimetacrins, und strukturverwandte Verbindungen
T1  - 9,9-Dimethyl-10-(3-dimethylaminopropyl)-9-silaacridane,a Sila-Analogue of Dimetacrine, and Structurally Related Compounds
N2  - Das Sila-Dimetacrin (3a), ein Sila-Analogon des Psychopharmakons Dimetacrin (2), und sein N,N-Diethylderivat 3 b sowie sein 3-Chlorderivat 3 c wurden, von den o-Halogenanilinen 4 a- c ausgehend, über die teilweise unbekannten Stufen 5 a- c bis 10a- d synthetisiert, in ihren Eigenschaften beschrieben und in ihrer Struktur über Elementaranalysen, \(^1\)H-NMR- und Massenspektren sichergestellt. Die Synthese des Zwischenproduktes Bis(2-bromphenyl)amin (9a) konnte optimiert werden.
N2  - Sila-dimetacrine (Ja), a sila-analogue of the psychotropic drug dimetacrine (2), and its N,N-diethyl derivative 3 b as well as its 3-chloro derivative 3 c were synthesized from o-haloanilines 4 a- c via the - partially unknown - intermediates S a- c to 10 a- d. Their properties are described and their structure is confirmed by eiemental analysis, \(^1\)H-NMR, and mass spectroscopy. The preparation of the intermediate bis(2-bromophenyl)amine (9a) could be improved.
KW  - Anorganische Chemie
Y1  - 1981
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-63691
ER  - 
TY  - JOUR
A1  - Christl, Manfred
A1  - Brunn, E.
T1  - Tetracyclo[4.1.0.0\(^{2,4}\).0\(^{3,5}\)]heptane aus 7,8-Diazatetracyclo[4.3.0.0\(^{2,4}\).0\(^{3,5}\)]non-7-enen
N2  - No abstract available
KW  - Organische Chemie
Y1  - 1981
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-58094
ER  - 
TY  - JOUR
A1  - Heinsen, Helmut
T1  - Regional differences in the distribution of lipofuscin in Purkinje cell perikarya : a quantitative Pigmentarchitectonic study of the Cerebellar Cortexof Senile Albino Rats
N2  - The distribution of lipofuscin in the perikarya of Purkin je cells of vermal and hemispheric lobules has been determined quantitatively in 7 rats, 30-38 months old, by the point-counting method. On the basis of morphologically and statistically significant differences a pigmentarchitectonics of the cerebellar cortex is established. The Purkinje cells of lobule VIa (Larsell 1952) are extremely lipofuscin-rich. The Purkinje cells of the hemispheres, lobules V, Vlb + c and VII contain considerable amounts of a finely granular lipofuscin, the Purkinje cells of lobules I-III and VIII- IXa a globular type of lipofuscin. The Purkinje cells of sublobule XI d c and X are lipofuscin-poor cells. Three types of lipofuscin ha ve been identified in the light microscope.
KW  - Medizin
KW  - Lipofuscin
KW  - Purkinje cells
KW  - Pigmentarchitectonics
KW  - Senile rat
Y1  - 1981
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-59904
ER  - 
TY  - JOUR
A1  - Scheer, Ulrich
A1  - Zentgraf, Hanswalter
A1  - Sauer, Helmut W.
T1  - Different chromatin structures in Physarum polycephalum: a special form of transcriptionally active chromatin devoid of nucleosomal particles
N2  - Nonnucleolar chromatin from interphase nuclei of Physarum polycephalum plasmodia occurs in two different structural configurations as seen in electron microscopic spread preparations. While the majority of the chromatin is devoid of nascent ribonucleoprotein (RNP) fibrils and compacted into nucleosomal particles, a minor proportion (10- 20%) is organized differently and reveals a smooth contour. It is this form of smooth chromatin which is rich in transcription units (mean length: 1.36±0.21 11m). Only occasionally are solitary nascent RNP fibrils observed which are associated with beaded strands of chromatin. In transcribed smooth chromatin nucleosomal particles are not only absent from the transcription units but also from their nontranscribed flan king regions, indicating that this special structural aspect is not merely a direct consequence of the transcriptional process. The existence of ca. 10- 20% of Physarum chromatin in the smoothly contoured form is discussed in relation to reports of a preferential digestibility of a similar proportion of Physarum chromatin by DNAse I (Jalouzot et al. , 1980) and to the altered configuration of "peak A" chromatin subunits after micrococcal nuclease digestion (Johnson et al., 1978a, b).
Y1  - 1981
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-33148
ER  - 
TY  - JOUR
A1  - König, Dorothea
T1  - Wortindex zum Psalterium Sinaiticum / Maria Dumitrescu, Sinajskij Paterik
N2  - Maria Dumitrescu, Sinajskij Paterik : Wortindex zum Psalterium Sinaiticum, Bucuresti, 1980
Y1  - 1981
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-38758
ER  - 
TY  - GEN
T1  - Jahresbericht 1980
T1  - Annual Report 1980
N2  - Die Entwicklung der Universitätsbibliothek Würzburg im Jahr 1980.
N2  - Annual Report of the University Library of Würzburg, 1980.
T3  - Jahresbericht der Universitätsbibliothek Würzburg - 1980 
KW  - Würzburg
KW  - Universitätsbibliothek
KW  - Bericht
KW  - Jahresbericht
KW  - Würzburg
KW  - University Library
KW  - Report
KW  - Annual Report
KW  - Wuerzburg
KW  - Wurzburg
Y1  - 1981
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-42232
ER  - 
TY  - JOUR
A1  - Christl, Manfred
A1  - Lanzendörfer, Ulrike
A1  - Freund, Silke
T1  - Olefinadditionen an 2,5-Diphenyl-1,3,4-oxadiazin-6-on
N2  - No abstract available
Y1  - 1981
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-41525
N1  - Prof. Siegfried Hünig zum 60. Geburtstag gewidmet
ER  - 
TY  - CHAP
A1  - Krüger, Hans-Peter
T1  - Nachuntersuchungen zur Ausbildung des Wollens
N2  - Dükers Ergebnisse zur Wirkung von zwangsläufiger Arbeit bei wollensschwachen Vpn konnten wieder eingebracht werden. Die Variation des Versuchsgeräts ergab, daß das Gelingen dieser Untersuchungen wesentlich von der methodisch einzuführenden Unausweichlichkeit der Situation abhängt. Je weniger dies verwirklicht wird, desto geringer ist der Leistungsanstieg, um so mehr tritt die Person des Vls in den Vordergrund, um so schwerer fällt es den Vpn, die Leistungssteigerung der eigenen Person zu attribuieren. Ferner konnte gezeigt werden, daß das Schreiben von Achten in freier und zwangsläufiger Arbeit zumindest dieselbe Wirkung auf andere Leistungen hat wie das direkte üben dieser Leistungen. Offensichtlich wird mit dieser Methode eine zentrale Funktion der Leistung geübt.
N2  - The effects of forced continuous activity on weak-willed slow learners, as shown by Düker, could be reproduced. Variation of the display apparatus cleared that the success of such tests essentially depends on the degree of inevitability imposed on the Ss by the situation. The less inevitable the situation, the lower becomes the increase in efficiency, the more the experimenter comes to the fore, and the harder it is on the Ss to attribute the increase to themselves. Moreover, the continuous writing of eights in free and in forced activity has at least the same bearing on other skills as practising these skills directly. Apparently, the method contributes to practising a central function of performance.
Y1  - 1981
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-40995
ER  - 
TY  - JOUR
A1  - Agranovsky, A. A.
A1  - Dolya, V. V.
A1  - Gorboulev, Valentin G.
A1  - Kozlov, J. V.
A1  - Atabekov, J. G.
T1  - Aminoacylation of barley stripe mosaic virus RNA: polyadenylate-containing RNA has a 3'-terminal tyrosine-accepting structure
N2  - Barley stripe mosaic virus (BSMV) RNA which was previously reported to contain poly(A) sequences (Agranovsky et al., 1978) can be specifically esterified with tyrosine in vitro in the presence of an aminoacyl-tRNA synthetase fraction from wheat embryos. All the three RNA components of the BSMV strain with a three-component genome (Norwich) and both RNA components of a two-component strain (Russian) can be tyrosylated. The poly(A)-containing (bound to oligo(dT)-cellulose) and poly(A)-deficient(not bound to oligo(dT)-cellulose) fractions of BSMV RNA display a similar amino acidaccepting ability. The nucleotide sequence which accepts tyrosine is coupled with the intact genomic polyadenylated BSMV RNA. The viral RNA isolated after sucrose density gradient centrifugation under drastic denaturing conditions retains its aminoacylating activity, which suggests that this activity is not due to the presence in a BSMV RNA preparation of a tyrosine tRNA associated with BSMV RNA. Inhibition of aminoacylation of the 3’-oxidized (treated with sodium metaperiodate) BSMV RNA suggests that the tyrosine-accepting structure is localized at the 3’ terminus of BSMV RNA molecules. It is shown that segments of different lengths obtained upon random fragmentation can be tyrosylated. The 3’-terminal (tyrosine-accepting) poly(A)+ segments can be isolated. The shortest segments of viral RNA capable of being aminoacylated [i.e., containing both tRNA-like structure and poly(A)] consists of approximately 150-200 nucleotides. The analysis of the oligonucleotides derived from individual BSMV RNA components labeled with 32P at the 3’ end revealed two types of 3’-terminal sequences different from poly(A). It is suggested that a poly(A) sequence is intercalated between a 3’-terminal tyrosineaccepting structure and the 5’-terminal portion of poly(A)+ BSMV RNA.
Y1  - 1981
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-32566
ER  - 
TY  - JOUR
A1  - Kozlov, J. V.
A1  - Gorboulev, Valentin G.
A1  - Kurmanova, A. G.
A1  - Bayev, Alexander A.
A1  - Shilov, A. A.
A1  - Zhdanov, V. M.
T1  - On the origin of the H1N1 (A/USSR/90/77) influenza virus
N2  - The influenza virus H1N1 (the A/USSR/90/77 strain) that reappeared in 1977 after the H1N1 influenza viruses had disappeared from the human population, is compared with the A/FM/1/47 and the A/FW/1/50 influenza viruses by the method of oligonucleotide mapping of individual segments of the viral RNAs. Seven genes of the A/USSR/90/77 virus appear to be very similar to the corresponding genes of the A/FW/1/50 virus, whereas the gene coding for the M protein displays considerable homology to the corresponding gene of the A/FM/1/47 virus. The data demonstrate that the A/USSR/90/77 strain is a recombinant virus.
KW  - influenza virus ; virion RNA segments ; oligonucleotide mapping ; gene reassortment
Y1  - 1981
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-32556
ER  - 
TY  - JOUR
A1  - Scheer, Ulrich
A1  - Sommerville, J.
T1  - Structural organization of nascent transcripts and hnRNA molecules in amphibian oocytes
N2  - Comparisons ofrelative lengths oflampbrush loops, nascent RNP transcripts and hnRNA molecules from oocytes of amphibia with different C-values show that there is an increasing trend in loop, and transcriptional unit, length with increase in genome size but no increasing trend with respect to RN A contour length.The formation of duplex regions and circles in RNP fibrils indicates that RNA processing may occur within the nascent fibrils. The hnRNA molecules from oocytes of the various amphibia readily form intermolecular duplex structures. These complementary sequences have a low kinetic complexity and are transcribed from highly repetitive sequences distributed throughout the genome. Their possible function is considered.
Y1  - 1981
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-39765
ER  - 
TY  - JOUR
A1  - Burschka, Christian
A1  - Schenk, W. A.
T1  - Die Kristallstruktur von Tetramethylammonium-Chloropentacarbonylwolframat
T1  - Substituted Halocarbonyl Metallates of Chromium, Molybdenum, and Tungsten. IV. Crystal Structure of Tetramethylammonium Chloropentacarbonyltungstate
N2  - Die Struktur von Tetramethylammoniumchloropentacarbonylwolframat wurde rontgenographisch aue Einkristalldaten bestimmt. Die Verbindung kristallisiert mit vier Formeleinheiten in del' monoklinen Elementarzelle (Raumgruppe P2Jc) folgender Dimensionen: a = 1111,3(4) pm, b = 1110,3(4) pm, c = 1204,1(3) pm, f3 = 99,63(3)°, V = 1464,8 . 106 pm' (R = 0,028). Das Anion besitzt annahernd C4v·Symmetrie mit d(W -C(ois» = 203 pm, d(WC( trans» = 197 pm, d(W-Cl) = 256,6 pm. Zwischen Kation undAnion treten keine ungewohnliche Kontakte auf.
N2  - The structure of tetramethylam~onium chloropentacarbonyltungstate has been determined from single crystal X-ray data. The compound crystallizes with four formula units in the monoclinic unit cell (space group P21!c) of the dimensions a = 1111.3(4) pm, b = 1110.3(4) pm c = 120-1.1(3) pm, fJ = 99.63(3)°, V = 1464.8x 1()6 pm" (R = 0.028). The anion possesses approximately C!v symmetry with the principal interatomic distances d(W -C(cis» = 203 pm, d(WC( trans)) = 197pm dew -Cl) = 256.6 pm. No unusual contacts between cation and anion have been found.
KW  - Chemie
Y1  - 1981
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-31417
ER  - 
TY  - JOUR
A1  - Albert, Bernhard
A1  - Berning, Wilfried
A1  - Burschka, Christian
A1  - Hünig, Siegfried
A1  - Martin, Hans-Dieter
A1  - Prokschy, Frank,
T1  - Transanulare Wechselwirkung des Azo-Chromophors inisodrinanalogen Systemen
T1  - Transanular Interactions of the Azo Chromophore in Isodrin-type Systems
N2  - No abstract available
KW  - Chemie
Y1  - 1981
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-31328
ER  - 
TY  - JOUR
A1  - Christl, Manfred
T1  - Benzvalen - Eigenschaften und Synthesepotential
N2  - No abstract available
Y1  - 1981
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-30041
ER  - 
TY  - JOUR
A1  - Zentgraf, H.
A1  - Müller, U.
A1  - Scheer, Ulrich
A1  - Franke, W. W.
T1  - Evidence for the existence of globular units in the supranucleosomal organization of chromatin
N2  - No abstract available
Y1  - 1981
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-34123
ER  - 
TY  - JOUR
A1  - Bona, Marion
A1  - Scheer, Ulrich
A1  - Bautz, Ekkehard K. F.
T1  - Antibodies to RNA polymerase II (B) inhibit transcription in lampbrush chromosomes after microinjection into living amphibian oocytes
N2  - Antibodies directed against RNA polymerase II (B) from Drosophila melanogaster were obtained from rabbit sera and, as monoclonal immunoglobulins, from mouse hybridomas and shown to cross-react with the amphibian enzyme protein. Localization by indirect immunofluorescence microscopy revealed the association of this enzyme with chromatin of interphase nuclei of amphibian cells and its absence in nucleoli. Purified immunoglobulins were microinjected in to nuclei ofliving vitellogenic oocytes of Ple1lrodeles waltlii and X enopus laevis and their effects on transcriptional processes were monitored by biochemical and light and electron microscopic stud ies. RNA polymerase II antibodies from rabbit sera caused a rapid and almost complete release of nascent transcripts from the chromatin axis of the loops of lampbrush chromosomes, followed by collapse of the loops and their retraction on the main chromosome axis. Monoclonal murine antibodies to the Iarge RNA polymerase II subunits also inhibited transcription in chromosome Ioops but appeared to inhibit initiation rather than elongation events. Activities of class land III RNA polymerases were not significantly affected by injection of antibodies to polymerase II, indicating immunological differences between the three RNA polymerases. The potential value of the in vitro test system described , as a very sensitive assay for detecting proteins involved in transcription in living cells, is discussed. 1
Y1  - 1981
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-33128
ER  - 
TY  - JOUR
A1  - Franke, Werner W.
A1  - Scheer, Ulrich
A1  - Krohne, Georg
A1  - Jarasch, Ernst-Dieter
T1  - The nuclear envelope and the architecture of the nuclear periphery
N2  - No abstract available
Y1  - 1981
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-33108
ER  - 
TY  - JOUR
A1  - Franke, Werner W.
A1  - Kleinschmidt, Jürgen A.
A1  - Spring, Herbert
A1  - Krohne, Georg
A1  - Grund, Christine
A1  - Trendelenburg, Michael F.
A1  - Stöhr, Michael
A1  - Scheer, Ulrich
T1  - A nucleolar skeleton of protein filaments demonstrated in amplified nucleoli of Xenopus laevis
N2  - The amplified, extrachromosomal nucleoli of Xenopus oocytes contain a meshwork of -4-nm-thick filaments, which are densely coiled into higher-order fibrils of diameter 30-40 nm and are resistant to treatment with high- and low-salt concentrations, nucleases (DNase I, pancreatic RNase, micrococcal nuclease), sulfhydryl agents, and various nonionic detergents. This filamentous "skeleton" has been prepared from manually isolated nuclear contents and nucleoli as weil as from nucleoli isolated by fluorescence-activated particle sorting. The nucleolar skeletons are observed in light and electron microscopy and are characterized by ravels of filaments that are especially densely packed in the nucleolar cortex. DNA as weil as RNA are not constituents of this structure, and precursors to ribosomal RNAs are completely removed from the extraction-resistant filaments by treatment with high-salt buffer or RN ase. Fractions of isolated nucleolar skeletons show specific enrichment of an acidic major protein of 145,000 mol wt and an apparent pi value of -6.15, accompanied in some preparations by various amounts of minor proteins. The demonstration of this skeletal structure in "free" extrachromosomal nucleoli excludes the problem of contaminations by nonnucleolar material such as perinucleolar heterochromatin normally encountered in studies of nucleoli from somatic cells. It is suggested that this insoluble protein filament complex forms a skeleton specific to the nucleolus proper that is different from other extraction-resistant components of the nucleus such as matrix and lamina and is involved in the spatial organization of the nucleolar chromatin and its transcriptional products. In studies of the organization of the interphase nucleus, considerable progress has been made in the elucidation of the arrangement of chromatin components and transcriptional products. However, relatively little is known about the composition and function of another category of nuclear structures, the nonnucleoproteinaceous architectural components that are insoluble in solutions of low and high ionic strength, despite numerous studies dedicated to this problem. Such structures include (a) the nuclear envelope and its pore complexes (I, 15, 18, 23, 37, 41), (b) a peripheral layer of insoluble protein ("lamina"; I, 15, 22, 23, 59), (e) certain skeletal proteins related to the chromosome "scaffold" described by Laemmli and coworkers (see references 2 and 3), and (d) ill-defined tangles of fibrillar structures of the nuclear interior that are collectively described as residual "matrix" (6, 21 ; for reviews, see references THE JOURNAL OF CEll BrOlOGY . VOlUME 90 AUGUST 1981 289-299 © The RockefeIler University Press · 0021 -9525/ 81 / 08/ 0289/ 11 $1 .00 4 and 12). The latter, preparatively
Y1  - 1981
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-33130
ER  - 
TY  - JOUR
A1  - Scheer, Ulrich
T1  - Identification of a novel class of tandemly repeated genes transcribed on lampbrush chromosomes of Pleurodeles waltlii
N2  - Electron microscope preparations of lampbrush chromosomes from oocytes of Pleurodeles waltl;; have revealed a new class of tandemly repeated genes. These genes are highly active, as judged by the close spacing of nascent transcripts. They occur in clusters of >100 copies and are transcribed in units containing roughly 940 base pairs of DNA that are separated by nontranscribed spacers of an estimated DNA content of 2,410 base pairs. The size and the pattern of arrangement of these transcription units can not be correlated with any of the repetitious genes so far described.
Y1  - 1981
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-33153
ER  - 
TY  - CHAP
A1  - Krüger, Hans-Peter
A1  - Kohnen, Ralph
T1  - Kognitive, emotionale und physiologische Determinanten sozialer Zustände
N2  - The psychological and physiological effects of a socially oriented sensitivity training were evaluated. It is shown that decreased physical distance as well as increased intimacy yields high activation, both in psychological measures (experienced stress) and in pulse frequences. One result (highly significant and replicated in other experiments) was paradoxical: when Ss had to caress the face of a heterosexual vis-a-vis, they reported high experienced stress, but pulse frequences dropped rapidely below the resting pulse. Some suggestions are made to explain these findings. The question arises whether an autonomic somatic process, induced by social Stimulation, but independent of the cognitive coping is responsible for these results.
KW  - Psychologie
Y1  - 1981
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-86055
ER  - 
TY  - JOUR
A1  - Treiber, Bernhard
A1  - Schneider, Wolfgang
T1  - Schulisches Lernen im sozialökologischen Kontext
N2  - No abstract available.
KW  - Lernen
KW  - Sozialökologie
Y1  - 1981
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-87271
ER  - 
TY  - CHAP
A1  - Schartl, A.
A1  - Schartl, Manfred
A1  - Anders, F.
T1  - Phenotypic conversion of malignant melanoma to benign melanoma and vice versa in Xiphophorus
N2  - No abstract available.
KW  - Schwertkärpfling
KW  - Krebs <Medizin>
Y1  - 1981
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-86662
ER  - 
TY  - BOOK
A1  - Wolf, Norbert Richard
A1  - Domröse, Gerd
A1  - Liebel, Hermann
T1  - List Sprachbuch 6 [Hauptband]
N2  - No abstract available
KW  - Deutschunterricht
KW  - Lehrmittel
Y1  - 1981
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-41688
ER  - 
TY  - BOOK
A1  - Ante, Ulrich
T1  - Politische Geographie
T1  - Political geography
N2  - No abstract available
KW  - Geopolitik
KW  - Einführung
KW  - Politische Geographie
Y1  - 1981
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-36058
SN  - 3-14-160278-6
ER  - 
TY  - JOUR
A1  - Werner, S.
A1  - Sebald, Werner
T1  - Immunological techniques for studies on the biogenesis of mitochondrial membrane proteins
N2  - no abstract available
KW  - Biochemie
Y1  - 1981
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-82044
ER  - 
TY  - CHAP
A1  - Krüger, Hans-Peter
A1  - Lehmacher, Walter
A1  - Wall, K. - D.
T1  - The Fourfold Table up to N=80
T1  - Die Vierfeldtafel bis N=80
N2  - No abstract available.
KW  - Psychologie
Y1  - 1981
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-87053
ER  - 
TY  - CHAP
A1  - Anders, F.
A1  - Scholl, E.
A1  - Schartl, Manfred
T1  - Environmental and hereditary factors in the causation of neoplasia, based on studies of the Xiphophorus fish melanoma system
N2  - Neoplasia in Xiphophorus can be classified into: a) a Jarge group triggered by carcinogens; b) a large group triggered by promoters; and c) a small group that develops "spontaneously" according to Mendelian Jaw. The process leading to susceptibility for neoplasia is represented by the disintegration of gene systems that normally protect the fish from neoplasia. Interpopulational arid interracial hybridization is the most effective process that Ieads to disintegration of the protective gene systems. Environmental factors may complete disintegration in somatic cells and thus may trigger neoplasia. The applications of the findings on Xiphophorus to humans are discussed.
KW  - Schwertkärpfling
KW  - Gen
KW  - Umweltfaktor
KW  - Tumor
Y1  - 1981
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-86402
ER  - 
TY  - CHAP
A1  - Anders, F.
A1  - Schartl, Manfred
A1  - Scholl, E.
T1  - Evaluation of environmental and hereditary factors in carcinogenesis, based on studies in Xiphophorus
N2  - Neoplasia in Xiphophorus can be classified into a) a large group that is triggered by carcinogens; b) a large group triggered by promoters; c) a small group that develops "spontaneously" following interpopulational and interracial hybridizations; and d) a small group that develops "spontaneously" following germ line mutation. The process leading to susceptibility for neoplasia is represented by the disintegration of gene systems that normally protect the fish from neoplasia. Hybridization is the most effective process that leads to disintegration of the protection gene systems. Environmental factors may complete disintegration and thus may trigger neoplasia. It is discussed whether the findings on Xiphophorus may also apply to humans.
KW  - Schwertkärpfling
KW  - Gen
KW  - Umweltfaktor
KW  - Carcinogenese
Y1  - 1981
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-72741
ER  - 
TY  - BOOK
A1  - Wolf, Nobert Richard
T1  - Althochdeutsch - Mittelhochdeutsch
N2  - No abstract available
KW  - Deutsch
KW  - Geschichte
Y1  - 1981
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-41654
SN  - 3-494-02133-3
ER  - 
TY  - CHAP
A1  - Kohnen, Ralph
A1  - Krüger, Hans-Peter
T1  - Soziale Situationen als experimentelle Bedingungen der Pharmakopsychologie
N2  - Summary (Social Situations as Experimental Conditions in Psychopharmacology): To reduce a great variability of drug effects in healthy subjects, stress conditions are used often in pharmacopsychology. However, empirical results show that the desired stress effects are failing. This paper suggests to realize social stress Situations as interactions between subjects, expecting higher challenging effects than experimentator-subject-interactions, usually used in experimental designs. Two experimental studies are reported: the call-upsituation and the group-therapy situation. The experimental effects were measured by changes of pulse-frequencies. The results indicate that in the two situations high and low dosages of tranquilizing drugs lead to comparable (and so predictable) effects only, if a Situation is high challenging for the experimental subjects. The call-up situation, which proves performance, challenges male subjects highly. The emotional or social competence demanding group-therapy situation is a high challenging situation for warnen. It is concluded that no situation is stressing a person generally. Depending from personality characteristics, differential stressor effects appear. Consequences for experiments in pharmacopsychology are discussed.
KW  - Soziale Situation
KW  - Psychopharmakologie
Y1  - 1981
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-86041
ER  - 
TY  - JOUR
A1  - Hommers, Wilfried
T1  - Berücksichtigung der Intelligenz im multiplen Zusammenhang von Persönlichkeitsmerkmalen, sozioökonomischen Daten und Schulniveau entbehrlich?
N2  - No abstract available
KW  - Sonderpädagogik / Zeitschrift
Y1  - 1981
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-43390
ER  - 
TY  - CHAP
A1  - Krüger, Hans-Peter
T1  - Differentielle Pharmakopsychologie ohne Differentielle Psychologie?
N2  - Die Differentielle Pharmakopsychologie stützt sich weitgehend auf Konzepte der Differentiellen Psychologie. Ihre Ergebnisse müssen sich deshalb auch voll der Diskussion stellen, in der die verwendeten Persönlichkeitskonzepte stehen. Es wird die Auffassung vertreten, daß diese Vorgehensweise nicht zwingend ist. Vielmehr sollte die Pharmakopsychologie die differentiellen Wirkungen ihrer experimentellen Anordnungen mit eigenen Methoden bestimmen. Sie leistet damit einen eigenständigen Beitrag zur Differentiellen Psychologie. Paradigmatisch für eine solche Vorgehensweise wird ein Experiment vorgestellt, in dem die Wirkung von Psychopharmaka (Tranquilizer, Stimulizer) auf Erleben und Leistung in einer Streßsituation (Lernen unter weißem Rauschen) untersucht wird. Dabei zeigt sich, daß die Wirkung in einen generellen Anteil und einen differentiellen Anteil des individuellen "copings" zerlegt werden muß. Die Konsequenzen für die pharmakopsychologische Methodik werden diskutiert.
Y1  - 1981
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-34163
ER  - 
TY  - JOUR
A1  - Wilhelm, Gernot
T1  - Zusammenschlüsse von Nuzi-Texten
N2  - no Abstract available
KW  - Nusi
KW  - Churritisch
KW  - Literatur
KW  - Aufsatzsammlung
KW  - Ausgrabung
KW  - Akkadisch
Y1  - 1981
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-70323
ER  - 
TY  - CHAP
A1  - Krüger, Hans-Peter
A1  - Kohnen, Ralf
A1  - Lienert, Gustav A.
T1  - Drei Forderungen zur Prüfung der Homogenität von Zentren bei Multicenter-Studien
N2  - Es wird argumentiert, daß bei der Prüfung der Homgenität von Zentren in mehrfaktoriellen Multicenter-Studien vor allem entscheidend ist, daß sich die Zentren in den faktoriellen Variablen nicht unterscheiden, deren Effekte in der späteren Auswertung interpretiert werden sollen. Dazu wird folgendes Procedere vorgeschlagen: (1) überprüfe, ob in allen Zentren die Randomisierungsbedingungen eingehalten wurden, (2) überprüfe, ob die Zentren homogen bezogen auf die eingebrachten Schichtvariablen (z.B. Geschlecht, Indikation) sind und (3) überprüfe, ob die Zentren homogen sind bezogen auf die Wechselwirkungen zwischen den eingebrachten faktoriellen Variablen. Es wird gezeigt, daß vor allem Forderung (3) für die Interpretationsfähigkeit der Ergebnisse von entscheidender Bedeutung ist. Möglichkeiten der statistischen Prüfung dieser Voraussetzungen werden an einem Beispiel aus der klinischen Prüfung eines Psychopharmakons vorgestellt.
KW  - Psychologie
Y1  - 1981
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-101730
ER  - 
TY  - CHAP
A1  - Ellgring, Johann Heinrich
T1  - Psychische Beanspruchung durch Sprache und Blickzuwendung in Gesprächs- und Leistungssituationen
N2  - Die Koordination von Blickverhalten und Sprechaktivität wurde unter folgender Hypothese untersucht: Die durch Sprechvorbereitung und Sprechaktivität bedingte kognitive Belastung führt dazu, daß die simultane Aufnahme bedeutsamer visueller Information reduziert wird. Generell wendet ein Sprecher nach der Darbietung einer verbalen Aufgabe den Blick von einer Informationsquelle zunehmend ab und wendet ihn erst zum Ende der gesprochenen Antwort wieder zu. Mit größerer Schwierigkeit der Aufgaben erhöht sich die Wahrscheinlichkeit einer Abwendung. Nach diesen und weiteren Ergebnissen scheinen Sprechen und Blickzuwendung zumindest teilweise ähnlichen Regeln zu folgen wie andere simultan ablaufende Tätigkeiten.
Y1  - 1981
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-42112
ER  - 
TY  - CHAP
A1  - Ellgring, Johann Heinrich
T1  - Entwicklungen in video-unterstützter Diagnostik und Therapie
N2  - No abstract available
Y1  - 1981
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-42127
ER  - 
TY  - CHAP
A1  - Clarke, A. H.
A1  - Wagner, H.
A1  - Ellgring, Johann Heinrich
T1  - Eine syntaktische Analyse von Sprechen und Blickverhalten bei dyadischer Interaktion
N2  - No abstract available
Y1  - 1981
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-42093
ER  - 
TY  - CHAP
A1  - Clarke, Andrew H.
A1  - Ellgring, Johann Heinrich
A1  - Wagner, Helmut
T1  - Analyse des Blickverhaltens in sozialen Situationen
N2  - Der vorliegende Beitrag behandelt inhaltliche und methodische Probleme einer Längsschnittstudie, die derzeit am MPI für Psychiatrie in München an depressiven Patienten durchgeführt wird. Diese Untersuchung hat einen diagnostischen und einen kommunikationstheoretischen Aspekt. Von diagnostischem Interesse sind die depressionsspezifischen Veränderungen des kommunikativen Verhaltens. Kommunikationstheoretisch gewendet lautet die Frage, wie sich der interne Zustand einer Person in ihrem Verhalten reflektiert. In diesem Beitrag wird die Fragestellung konzentriert auf tonische Eigenschaften des Blickverhaltens im Interaktionsprozeß und deren Stabilität im Krankheitsverlauf. Zunächst wird die theoretische Grundlage referiert, die wir für das Blickverhalten entwickelt haben. Im zweiten Abschnitt wird auf Datenerhebung und Reliabilitätskontrolle eingegangen. Die Struktur der Daten bestimmt die Auswertungsmethoden. Einige der Methoden, mit denen wir derzeit arbeiten, werden im Zusammenhang mit umschriebenen Problemstellungen erläutert: Deskription und Interpretation des tonischen Blickverhaltens depressiver Patienten im Krankheitsverlauf (Abschnitt 3). Zusammenhang der individuellen Blickniveaus von Interaktionspartnern (Abschnitt 4) Deskription eines Dialogs (Interviews) als Sequenz von distinkten Zuständen. In den Zuständen werden Sprech- und Blickverhalten beider Interaktionspartner miteinander kombiniert (Abschnitt 5) Analyse der intraindividuellen Wechselwirkung zwischen Blick- und Sprechverhalten (Abschnitt 6). Die Abschnitte 3 mit 6 werden durch vorläufige Ergebnisse illustriert.
Y1  - 1981
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-43012
ER  - 
TY  - CHAP
A1  - Ellgring, Johann Heinrich
A1  - Winkler, Barbara
T1  - Codierung und Analyse der Sprachinhalte klinischer Interviews
N2  - No abstract available
Y1  - 1981
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-46273
ER  - 
TY  - JOUR
A1  - Ellgring, Johann Heinrich
T1  - Nonverbal communication - A review of research in Germany
N2  - This paper presents an overview of the research on nonverbal communication that has appeared in the German-language literature during the past decade, and gives some treatment of its relationship to Ausdruckspsychologie. Empirical studies, recent theoretical issues, and methodological developments are discussed. - Although nonverbal communication often plays an essential role in diagnosis and treatment, it has been widely neglected in academic training for the past 20 years. This inconsistency may partly be due to the outright rejection of the classical Ausdruckspsychologie during the 1960's. In order to avoid the fate of Ausdruckspsychologie, it will be necessary to extend our knowledge of nonverbal communication by means of further methodological development and empirical investigation
Y1  - 1981
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-42022
ER  - 
TY  - JOUR
A1  - Schneider, Wolfgang
T1  - Rechtschreibdiagnose in der Grundschule - Theoretische und empirische Analysen zur spezifischen Problematik
T1  - Specific difficulties in assessing spelling competencies in elemantary schools
N2  - Theoretische Analysen zum Problem des Recht-Schreibens weisen darauf hin, daß weniger Intelligenzmerkmale als vielmehr Gedächtnis'eistungen bei dem Erwerb der Schriftsprache von Bedeutung sind. Daraus folgt, daß für die Prüfwörter in normierten Rechtschreibtests zumindest hinreichende Vorkommensfrequenz gewährleistet sein sollte. Diese Frage wird in der vorliegenden Untersuchung am Beispiel des Allgemeinen Schulleistungstests überprüft: für die ausgewählten Klassenstufen kann gezeigt INerden, daß die Vorkommenshäufigkeit der PrüfWÖfter nicht ausreicht und damit wenig geeignet ist, um die tatsächliche Rechtschreibfertigkeit zu erfassen. Der Vergleich mit mehreren eng am Curriculum orientierten Diktatproben kann gleichzeitig die Schwierigkeiten verdeutlichen, die dann entstehen, wenn zuverlässige Bestimmungen der individuellen Rechtschreibkompetenz vorgenommen werden sollen.
N2  - While there seems to be a long tradition in educationalliterature postulating astriet connection between spetting ability and test i ntelligence , recent theoretical analyses of the spetting process have emphasized the importance of basic memory skills. As a consequence ward frequency should be controlled in order to test individual spelUng competence. For a specific norm-oriented speUing test the empirical analysis can show that the importance of sufficient ward frequencv has been underestimated. The comperison with four other criterion.ariented spelling tests proves that the norm.ariented procedure cannot assess the true spelling competence; but it shows, tao, the general difficulty to come to a reliable estimation of individual spetting ,kills.
KW  - Psychologie
Y1  - 1981
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-50535
ER  - 
TY  - CHAP
A1  - Ruhe, Ernstpeter
T1  - Appendice: Textes d'Arthur Adamov des années 1926 à 1929. Edition des premiers textes.
N2  - No abstract available
KW  - Adamov
KW  - Arthur
KW  - Textsammlung
KW  - Adamoff
Y1  - 1981
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-43964
ER  - 
TY  - JOUR
A1  - Sirén, Anna-Leena
T1  - Differences in central actions of arachidonic acid and prostaglandin F\(_{2\alpha}\) between spontaneously hypertensive and normotensive rats
N2  - Prostag1andin F\(_{2\alpha}\) (PGF\(_{2\alpha}\)) is one of the most common metabo1ites of arachidonic acid (M) in rat brain. When administered intracerebroventricularly (i.c.v.) to rats, both AA and PGFal exert dose-related hypertensive, tachycardic and hyperthermic effects. Metabolie alterations in the endogenaus formation of some prostaglandins in the brain-stem of spontaneously hypertensive rats (SHR) have been reported. Therefore the central effects of AA and PGF \(_{2\alpha}\) on blood pressure, heart rate and body temperature were studied both in SHR and nonootensive Wistar rats (NR) under urethane-anaesthesia. The hypertensive effect of AA i.c.v. (0.01-100 \(\mu\)g/rat) was larger in magni tude in SHR than in NR, but there was no significant difference in the M-induced changes of heart rate and body temperature between the groups. Pretreatment of NR wi th soditm1 :meclofenamate (1 mg/rat i.c.v.) antagonised the central effects of M indicating that these effects are not due to M itself but to its conversion to prostaglandins. Unlike the effects of AA, the central hypertensive, tachycardic and hyperthennic responses to PGF\(_{2\alpha}\) (0.5-50 l-lg/rat i.c.v .) were significantly attenuated in SHR. The present results obtained with M are conpatible with the previous assumption that the synthesis of prostaglandins in the brain of SHR might differ from that in NR. The results also demonstrate that the central effects of PGF\(_{2\alpha}\) are reduced in SHR.
KW  - Neurobiologie
Y1  - 1982
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-63324
ER  - 
TY  - JOUR
A1  - Schairer, H. U.
A1  - Hoppe, J.
A1  - Sebald, Walter
A1  - Friedl, P.
T1  - Topological and functional aspects of the proton conductor, F\(_0\), of the Escherichia coli ATP-synthase
N2  - The isolated H\(^+\) conductor, F\(_0\) , of the Escherichia co1i ATP-synthase consists of three subunits, a, b, and c. H\(^+\) -permeable liposomes can be reconstit~ted with F\(_0\) and lipids; addition of F\(_1\)-ATPase reconstitutes a functional ATP-synthase. Mutants with altered or misslng F\(_0\) subunits are defective in H\(^+\) conduction. Thus, all three subunits are necessary for the expression of H\(^+\) conduction. The subunits a and b contain binding sites for F\(_1\)• Computer calculations, cross-links, membrane-permeating photo-reactive labels, and proteases were used to develop tentative structural models for the individual F\(_0\) subunits.
KW  - Biochemie
Y1  - 1982
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-62721
ER  - 
TY  - JOUR
A1  - Sebald, Walter
A1  - Friedl, P.
A1  - Schairer, H. U.
A1  - Hoppe, J.
T1  - Structure and genetics of the H\(^+\)-conducting F\(_0\) portion of the ATP synthase
N2  - The ATP synthase occurs in remarkably conserved form in procaryotic and eucaryotic cells. Thus, our present knowledge of ATP synthase is derived from sturlies of the enzyme from different organisms, each affering specific experimental possibilities. In recent tim es, research on the H\(^+\) -conducting F0 part of the ATP synthase has been greatly stimulated by two developments in the Escherichio coli system. Firstly, the purification and reconstitution of the whole ATP synthase as weil as the proton conductor Fa from E. coli have been achieved. These functionally active preparations are well defined in terms of subunit composition, similar to the thermophilic enzyme from PS-3 studied by Kagawa's group.u Secondly, the genetics and the molecular cloning of the genes of all the F\(_0\) subunits from E. coli yielded information on the function of subunit polypeptides and essential amino acid residues. Furthermore, the amino acid sequence of hydrophobic F\(_0\) subunits, which are difficult to analyze by protein-chemical techniques, could be derived from the nucleotide sequence of the genes. These achievements, which shall be briefly summarized in the next part of this communication, provide the framework to study specific aspects of the structure and function of the F\(_0\) subunits.
KW  - Biochemie
Y1  - 1982
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-62733
ER  -