TY - JOUR
A1 - Leininger, H.
A1 - Lanzendörfer, F.
A1 - Christl, Manfred
T1 - Über die Reduktion des Benzvalenozonids zum cis-1,3-Cyclobutandimethanol mit LiAlH\(_4\)
N2 - No abstract available
KW - Organische Chemie
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-58130
ER -
TY - JOUR
A1 - Leininger, H.
A1 - Christl, Manfred
A1 - Wendisch, D.
T1 - Über die Oxidation von Benzvalen mit Singulett-Sauerstoff zum Bicyclo[1.1.0]butan-endo,endo-2,4-dicarbaldehyd
N2 - No abstract available
KW - Organische Chemie
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-58142
ER -
TY - JOUR
A1 - Christl, Manfred
A1 - Lanzendörfer, F.
A1 - Peters, K.
A1 - Peters, E.-M.
A1 - Schnering, H. G. von
T1 - Die Reaktionen von 2,5-Diaryl-1,3,4-oxadiazin-6-onen mit trans-Cycloocten, cis,trans-Cyclooctadien und Cyclopropenen
N2 - The transient [4+2]-cycloadducts from the title components eliminate nitrogen to form a 3,4-dihydro-2-pyrone derivative, a tricyclic cyclobutanone derivative and 2,5-dihydrooxepin-2-one derivatives, respectively.
KW - Organische Chemie
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-58156
ER -
TY - JOUR
A1 - Hoppe, J.
A1 - Friedl, P.
A1 - Schairer, H. U.
A1 - Sebald, Walter
A1 - Meyenburg, K. von
A1 - Jorgensen, B. B.
T1 - The topology of the proton translocating F\(_0\) component of the ATP synthase from E. coli K12: studies with proteases
N2 - The accessibility of the three F\(_0\) subunits a, b and c from the Escherichia coli Kll A TP synthase to various proteases was studied in F\(_1\)-depleted inverted membrane vesicles. Subunit b was very sensitive to all applied proteases. Chymotrypsin produced a defined fragment of mol. wt. 1S 000 which remained tightly bound to the membrane. The cleavage site was located at the C-terminal region of subunit b. Larger amounts of proteases were necessary to attack subunit a (mol. wt. 30 000). There was no detectable deavage of subunit c. It is suggested that the major hydrophilic part of subunit b extends from the membrane into the cytoplasm and is in contact with the F\(_1\) sector. The F\(_1\) sector was found to afford some protection against proteolysis oftheb subunit in vitro andin vivo. Protease digestion bad no influence on the electro-impelled H\(^+\) conduction via F\(_0\) bot ATP-dependent H\(^+\) translocation could not be reconstituted upon binding of F\(_1\)• A possible role for subunit b as a linker between catalytic events on the F\(_1\) component and the proton pathway across the membrane is discussed.
KW - Biochemie
KW - protein pathway
KW - ATPase mutants
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-62718
ER -
TY - JOUR
A1 - Burschka, Christian
A1 - Akguen, Eyup
A1 - Pindur, Ulf
T1 - Zur Struktur von (Pyrazolinonyl)-(hydroxypyrazolylium)methanperchloraten NMR-,IR-spektroskopische Studien und Kristallstruktur
T1 - The structure of (Pyrazolinonyl)-(hydroxypyrazolylium)methaneperchlorates NMR, IR spectroscopic studies and crystal structure
N2 - No abstract available
KW - Chemie
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-46800
ER -
TY - BOOK
A1 - Wehgartner, Irma
T1 - Attisch weißgrundige Keramik - Maltechniken, Werkstätten, Formen und Verwendung
N2 - Die vorliegende Untersuchung attisch weißgrundiger Keramik ist die etwas erweiterte Fassung meiner Dissertation, die im Wintersemester 1979/80 von der Philosophischen Fakultät I der Julius-Maximilians-Universität Würzburg angenommen worden ist.
KW - Attika
KW - Weißgrundige Vase
KW - Geschichte
KW - Weißgrundige Vasenmalerei
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-51078
SN - 3-8053-0565-6
N1 - Teilw. zugl. Würzburg, Univ., Diss. 1980
ER -
TY - JOUR
A1 - Neumann-Haefelin, D.
A1 - Rethwilm, Axel
A1 - Bauer, G.
A1 - Gudat, F.
A1 - zur Hausen, H.
T1 - Characterization of a foamy virus isolated from Cercopithecus aethiops lymphoblastoid cells
N2 - A virus derived from cells of a Iymphoblastoid line originating from the lymph node of a healthy African green monkey was characterized as a typical member of the foamy virus subgroup of rctroviridac by its morphological, physicochemical, biological and biochemical properties (reverse transcriptase actvity). Besides the usual host range of foamy viruses, the isolated strain revealed a remarkable T -lymphotropism, distinguishing it from the prototypes of foamy viruses previously isolated from African green monkeys. Two foamy virus infectious are demonstrated in human contacts of the African green monkey colony, with the animal barbauring the isolate.
KW - Virologie
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-61538
ER -
TY - JOUR
A1 - Sagelsdorff, P.
A1 - Lutz, Werner K.
A1 - Schlatter, C.
T1 - The relevance of covalent binding to mouse liver DNA to the carcinogenic action of hexachlorocyclohexane isomers
N2 - [\(^3\)H]Hexachlorocyclohexane (HCH) was synthesized by chlorination of [\(^3\)H]benzene prepared by catalytic tritiation of benzene with tritiated water. The isomers of HCH were separated by adsorption chromatography on silica gel. In order to determine the covalent binding to DNA, [\(^3\)H]HCH was administered to male mice by oral gavage, and liver DNA was isolated via cbromatin. The specific radioactivity of the DNA was nonnalized by the dose administered and expressed in the molar units of the Covalent binding index, CBI = DNA damage/dose = (\(\mu\)mol bound HCH/mol DNA nucleotide)/(mmol HCH administered/kg body weight). CBI values of - 0.2 were found 10 h after the administration of alpha- and gamma-HCH. Enzymatic digestion of the DNA to the nucleosides and h.p.l.c. analysis revealed that - 40% of the radioactivity co-migrated with the natural nucleosides. At elution volumes known to contain the more lipophilic carcinogen-nucleoside adducts, - 10% of the radioactivity could be detected. The remaining 50% of th,e radioactivity eluted with the front, representing a mixture of oligonucleotide- HCH adducts and/or hydrophilic degradation products which were strongly bot not covalently associated with intact DNA. Therefore, a true CBI of 0.02-0.1 must be expected both for alpha- and gamma-HCH. This CBI is by a factor of 10\(^5\) -10\(^6\) below the value found with the strongest DNAbinding carcinogens like aflatoxin B1 or dimethylnitrosamine and is unlikely to be decisive for the liver tumor induction in mice because of the foUowing additional findings: (i) both isomers gave rise to similar Ievels of DNA darnage although the alpha-isomer is a much morepotent tumor inducer. This similarity was seen not only at the time of mäximum binding but up to 10 days after oral administration; (ii) three mouse strains with apparently different susceptibility to tumor induction by gamma-HCH could not be distinguished with respect to DNA binding; (iii) the level of DNA binding of alpha-HCH (CBI = 0.02-0.1) is more than three orders of magnitude lower than would be expected if the mechanism of tumor induction was by genotoxicity mediated by DNAbinding. For a preliminary investigation on a potential stimulatory effect on liver DN A replication and ceU division, [\(^{14}\)]thymidine was admlnistered i.p. 3.5 h before sacrifice of the [\(^3\)H]HCH-treated mice. The alpha-isomer was found to be more potent than the gamma-isomer in this respect. Taken together, our data allow the conclusion that the non- mutational processes must be more important for the carcinogenicity of HCH.
KW - Toxikologie
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-61039
ER -
TY - JOUR
A1 - Jauch, A.
A1 - Lutz, Werner K.
T1 - In vivo assay for somatic point mutations induced by genotoxic carcinogens: incorporation of [\(^{35}\)S]methionine into a rat liver cytochrome b\(_5\) normally lacking sulphur-containing amino acids
N2 - The trypsin fragments of rat liver microsomal cytochron1e b\(_5\) (Tb\(_5\)) lack both methionine (met) and cysteine (cys), i.e., the sulphur-containing antino acids. Tb\(_5\) should therefore contain no 358-radioactivity after isolation from animals treated wHh [\(^{35}\)S]met or [\(^{36}\)S]cys. If, however, the nucleic acids coding for this polypeptide have been damaged by a genotoxic carcinogen, a miscoding could result in an incorporation of met or cys into the polypeptide so that Tb\(_8\) could now be \(^{36}\)S-radiolabelled. Two experiments are descrihed. the first one where a toxic regimen of N -nitrosomorpholine (NNM) to rats resulted in a significant increase of \(^{35}\)S-radioactivity in the Tbs of liver microsomes, and a second experiment with a non-toxic regimen of N,N diethylnitrosamine (DENA), where no increase was observable.
KW - Toxikologie
KW - MammaJian mutagenicity test
KW - Pointmutation
KW - Protein coding
KW - Cytochrome b5
KW - Amino acid composition
KW - Rat Iiver microsomes
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-61047
ER -
TY - JOUR
A1 - Meier-Bratschi, A.
A1 - Lutz, Werner K.
A1 - Schlatter, C.
T1 - Methylation of liver DNA of rat and mouse by N-nitrosodimethylamine formed in vivo from dimethylamine and nitrite
N2 - The extent of formation of N-nitrosodimethylaminc {NDMA) in the stomachs of rats and mice after sirnultancous oral administration of [\(^{14}\)C]dimethylamine and potassium nitrite was determined by measuring the methylation of liver DNA. With doses of around 1 mg dimethylamine hydrochloride/ kg body weight and 50 mg potassium nitrite/kg body weight. 0,8 % of the amine was nitrosated on average. The individual fluctuations ranged from 0.2 to 1.30% in the rat and from 0.2 to 1.9% in the mouse. Simultaneous administration of 50 mg sodium ascorbate (vitamin Cl/kg body weight inhibited the nitrosation by ahout 80% while 50 mg \(\alpha\)-tocopherol acetate [Vitamin E)/kg body weight reduced the nitrosation by about a half. Assuming similar kinctics and conditions of nitrosation in rats and man. a comparison of the formation of NDMA in vivo from dietary dimethylamine and nitrite with the estimated human uptake of preformed N DMA revealed that in vitro formation in the stomach of man is probably negligible.
KW - Toxikologie
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-61052
ER -
TY - JOUR
A1 - Tacke, Reinhold
A1 - Strecker, M.
A1 - Lambrecht, G.
A1 - Moser, U.
A1 - Mutschler, E.
T1 - (2-Aminoethyl)-cycloalkylphenylsilanole: Bioisosterer C/Si-Austausch bei Parasympatholytika vom Typ des Trihexyphenidyls, Cycrimins und Procyclidins
T1 - (2-Aminoethyl)cycloalkylphenylsilanols: Bioisosteric C/Si Exchange in Parasympatholy1ics of lhe Trihexyphenidyl, Cycrimine, and Procyclidine Type
N2 - Die Synthese der (2-Aminoethyl)cycloalkylphenylsilanole Sb (Sila-Trihexyphenidyl), 6b (SilaCycrimin), 7 b (Sila-Procyclidin) und Sb wird beschrieben. Sb- Sb wurden - ausgehend von Cl\(_2\)(C\(_6\)H\(_5\))SiCH = CH\(_2\) (9) - durch eine fünfstufige Reaktionsfolge mit einer Gesamtausbeute von 32- 40% erhalten. Am isolierten Ileum des Meerschweinchens wurden die C/Si-Paare Sa, b- 8a, b vergleichend auf ihre antimuskarinische Aktivität geprüft. Die durch die Sila-Substilution von Sa-8a erreichte Zunahme der Affinität zum Muskarinrezeptor ist deutlich weniger ausgeprägt als bei den strukturverwandten C/Si-Paaren I a, b- 4a, b.
N2 - Thc synthesis of thc (2-aminoethyl)cycloalkylphenylsilanols Sb (sila-trihexyphenidyl), 6b (silacycrimine), 7b (sila-procyclidine), and Sb is described. Starting with Cl2(C6H5)SiCH = CH2 (9), Sb- 8 b were obtained by five reaction steps with a total yield of 32- 40%. The C/Si pairs Sa,b- 8a, b were tested for antimuscarinic activity on the isolated guinea-pig ileum. Thc increase of affinity for the muscarinic reccptor caused by sila-substitution of S a- 8a is less marked than in the case of the structurally related C/Si pairs la,b-4a,b.
KW - Anorganische Chemie
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-63741
ER -
TY - JOUR
A1 - Tacke, Reinhold
A1 - Lange, H.
T1 - Thermisch induzierte Umlagerung von (Acyloxymethyl)- diorganylsilanen
T1 - Thermally Induced Rearrangement of (Acyloxymethyl)diorganylsilanes
N2 - Die (Acyloxymethyl)diorganylsilane R\(^1\)R\(^2\)Si(H)CH\(_2\)OC(O)R\(^3\) (2a- d) unterliegen einer thermisch induzierten Umlagerung zu den entsprechenden Acyloxy(methyl)diorganylsilanen R\(^1\)R\(^2\)Si(CH\(_3\))OC(O)R\(^3\) (3a- d). Diese Reaktion beinhaltet formal einen Austausch des am Silicium gebundenen Wasserstoffs mit dem am Kohlenstoff gebundenen Acyloxy-Rest. Bezüglich der 1,2- Wasserstoff-Verschiebung konnte experimentell ein intramolekularer Prozeß bewiesen werden.
N2 - The (acyloxymethyl)diorganylsilanes R\(^1\)R\(^2\)Si(H)CH\(_2\)OC(O)R\(^3\) (2a-d) rearrange to the corresponding acyloxy(methyl)diorganylsilanes R\(^1\)R\(^2\)Si(CH\(_3\))OC(O)R\(^3\) (3a-d). This reaction is formally equivalent to an exchange of the hydrogen bound to silicon and the acyloxy group bound to carbon. The 1 ,2-hydrogen shift could be shown experimentally to be an intramolecular process.
KW - Anorganische Chemie
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-63752
ER -
TY - JOUR
A1 - Hacker, Jörg
A1 - Hughes, C.
A1 - Hof, H.
A1 - Goebel, W.
T1 - Cloned hemolysin genes from Escherichia coli that cause urinary tract infection determine different levels of toxicity in mice
N2 - After intraperitoneal injection of mice with Escherichia coli strains isolated from patients with urinary tract infections, the mortality due to hemolytic (Hly+) and nonhemolytic (Hiy-) isolates was 77 and 40%, respectively. Deletion of the chromosomal hemolysin (h/y) determinant in an E. co/i 06:K15:H31 urinary tract infection strain led to a significant reduction in toxicity for mice, and its reintroduction on a recombinant plasmid partially restored the original toxicity. Although introduction of the cloned plasmid pHiy152-encoded hly determinant into the Hly- E. coli 06 mutant strain increased toxicity by only a marginal degree, transformation with the cloned chromosomal hly determinants from two E. coli strains of serotypes 018ac:K5:H- and 075:K95:H? resulted in markedly greater toxicity, even exceeding that of the original Hly+ E. coli 06 wild-type strain.
KW - Infektionsbiologie
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-59330
ER -
TY - JOUR
A1 - Hughes, C.
A1 - Hacker, Jörg
A1 - Roberts, A.
A1 - Goebel, W
T1 - Hemolysin production as a virulence marker in symptomatic and asymptomatic urinary tract infections caused by Escherichia coli
N2 - Potential virulence, as defined by combined Ievels of adhesion to urinary epithelial cells, serum resistance, and mouse toxicity, was assessed for Escherichia coli strains causing symptomatic and asymptomatic urinary tract infections in relation to the carriage of hemolysin and other suspected virulence determinants. Hemolysin production (Hly), associated with certain 0 (04, 06, 018, and 075), K (5), and hemagglutination (VI and VII) antigenic types but not colicin V production (Cva), was evident in 83 and 60% ofisolates in groups possessing high potential virulence andin only 11 and 6% of those with low virulence. Strains of particular 0-types were not more virulent per se, but among the serotypes, specific combinations of virulence factors appeared decisive, e.g., 018 HAVI B/D/G Hly+ K5+t- and 018 HAIIIIIVBN Hly- Cva +t- Kl +t- strains were, respectively, of high and low potential virulence. Isolates with high potential virulence were found to a similar extent in symptomatic and asymptomatic infections.
KW - Infektionsbiologie
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-59346
ER -
TY - JOUR
A1 - Kreft, Jürgen
A1 - Burger, Klaus J.
A1 - Goebel, Werner
T1 - Expression of antibiotic resistance genes from Escherichia coli in Bacillus subtilis
N2 - Bifunctional recombinant plasmids were constructed, comprised of the E. coli vectors pBR322, pBR325 and pACYC184 and different plasmids from Gram-positive bacteria, e.g. pBSU161-1 of B. subtilis and pUB110 and pC221 of S. aureus. The beta-lactamase (bla) gene and the chloramphenicol acetyltransferase (cat) gene from the E. coli plasmids were not transcribed and therefore not expressed in B. subtilis. However, tetracycline resistance from the E. coli plasmids was expressed in B. subtilis. Transcription of the tetracycline resistance gene(s) started in B. subtilis at or near the original E. coli promoter, the sequence of which is almost identical with the sequence recognized by σ55 of B. subtilis RNA polymerase.
KW - Biologie
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-60600
ER -
TY - JOUR
A1 - Kreft, Jürgen
A1 - Berger, Harald
A1 - Härtlein, Michael
A1 - Müller, Bodo
A1 - Weidinger, Gerhard
A1 - Goebel, Werner
T1 - Cloning and expression in Escherichia coli and Bacillus subtilis of the hemolysin (cereolysin) determinant from Bacillus cereus
N2 - From a cosmid gene bank of Bacillus cereus GP4 in Escherichia coli we isolated clones which, after several days of incubation, formed hemolysis zones on erythrocyte agar plates. These clones contained recombinant cosmids with B. cereus DNA insertions of varying lengths which shared some common restriction fragments. The smallest insertionwas recloned as aPstl fragment into pJKK3-1, a shuttle vector which repücates in Bacillus subtilis and E. coli. When this recombinant plasmid (pJKK3-1 hly-1) was transformed into E. coli, it caused hemolysis on erythrocyte agar plates, but in liquid assays no extemal or intemal hemolytic activity could be detected with the E. coli transformants. B. subtilis carrying the same plasmid exhibited hemolytic activity at Ievels comparable to those ofthe B. cereus donor strain. The hemolysin produced in B. subtilis seemed to be indistinguishable from cereolysin in its sensitivity to cholesterol, activation by dithiothreitol, and inactivation by antibodies raised against cereolysin. When the recombinant DNA carrying the cereolysin gene was used as a probe in hybridization experiments with chromosomal DNA from a streptolysin 0-producing strain of Streptococcus pyogenes or from üsteriolysin-producing strains of Usteria monoeytogenes, no positive hybridization signals were obtained. These data soggest that the genes for these three SH-activated cytolysins do not have extended sequence homology.
KW - Biologie
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-60596
ER -
TY - JOUR
A1 - Härtlein, Michael
A1 - Schiessl, Sigrid
A1 - Wagner, Wilma
A1 - Rdest, Ursula
A1 - Kreft, Jürgen
A1 - Goebel, Werner
T1 - Transport of hemolysin by Escherichia coli
N2 - No abstract available
KW - Biologie
KW - Hemolysin
KW - Escberichia coli
KW - Gene cloning
KW - Expression
KW - Transport
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-60619
ER -
TY - JOUR
A1 - Heinsen, Helmut
A1 - Heinsen, Y. L.
T1 - Quantitative studies on regional differences in Purkinje cell dendritic spines and parallel fiber synaptic density
N2 - No abstact available
KW - Medizin
KW - Cerebellar cortex
KW - Albino rats
KW - Quantitative anatomy
KW - Purkinje cells
KW - Spines
KW - Parallel fiber synapses
KW - Regional differences
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-59917
ER -
TY - JOUR
A1 - Heinsen, Helmut
A1 - Heinsen, Y. L.
T1 - Cerebellar capillaries: qualitative and quantitative observations in young and senile rats
N2 - Ultrastructural changes including reduced electron density, reduction in polysemes and cisternae of rough endoplasmic reticulum occur in the cytoplasrn of endothelial cells and pericytes in the cerebellar cortex of senile virgin female Han: WIST-rats in cornparison to 3-month old virgin rats. Processes of pericytes cover less of the capillary surface in the cerebellar cortex of senile rats; moreover, arithmetic and harmonic mean thickness of the endothelium and relative volume of mitochondria in endothelial cells and pericytes are reduced, w hereas the luminal diameter of the capillaries, harmonic and arithmetic mean thickness of pericytes and their processes and of the basal laminae between endothelial cells and astrocytes (abbreviated BAL 1), pericytes and astrocytes (BAL 2) and endothelial cells and pericytes (BAL 3) increase. The increase in harmonic mean thickness of the basal laminae is statistically significant (α<=0.05) and compensates for a decrease in thickness of capillary endothelium. Consequently, the total barrier mass and thickness of cerebellar cortical capillaries in senile animals is higher than in young individuals.
KW - Medizin
KW - Capillaries
KW - Blood-brain barrier
KW - Quantitative anatomy
KW - Cerebellar cortex
KW - Senile rats
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-59924
ER -
TY - JOUR
A1 - Herbert, Michael
T1 - Elektronenmikroskopisch-morphometrische Untersuchungen am Nierenhauptstiick männlicher und weibliche Ratten nach Kastration und Testosteronsubstitution
T1 - Electron Microscopic and Morphometric Study on the Renal Proximal Tubule of Male and Female Rats Following Castration and Substitution with Testosterone
JF - Zeitschrift für mikroskopisch-anatomische Forschung
N2 - No abstract available.
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-127682
VL - 97
IS - 2
ER -
TY - JOUR
A1 - Tacke, Reinhold
A1 - Linoh, Haryanto
A1 - Stumpf, Burghard
A1 - Abraham, Wolf-Rainer
A1 - Kieslich, Klaus
A1 - Ernst, Ludger
T1 - Mikrobiologische Umwandlung von Silicium-Verbindungen: Enantioselektive Reduktion von Acetessigsäure-(trimethylsilylalkyl)estern und deren Carba-Analoga
T1 - Microbiological Transformation of Silicon Compounds: Enantioselective Reduction of Trimethylsilylalkyl Acetoacetates and their Carba-Analogues
JF - Zeitschrift für Naturforschung B
N2 - The trimethylsilylalkyl acetoacetates 1 b and 2 b as well as their carba analogues 1 a and 2 a have been reduced microbiologically by Kloeckera corticis (ATCC 20109), leading to the corresponding ( + )-3(S)-hydroxybutanoates 3b, 4b, 3a, and 4a. The enantiomeric purity was found to be 80% (3a, 3b, 4b) and 65% (4a), respectively. The reduction of lb and 2b is - to our knowledge - the first example for a controlled microbiological transformation of organosilicon substrates.
KW - enantioselective reduction
KW - microbiological transformation
KW - silicon compounds
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-128304
VL - 38
IS - 5
ER -
TY - GEN
T1 - Jahresbericht 1982
T1 - Annual Report 1982
N2 - Die Entwicklung der Universitätsbibliothek Würzburg im Jahr 1982.
N2 - Annual Report of the University Library of Würzburg, 1982.
T3 - Jahresbericht der Universitätsbibliothek Würzburg - 1982
KW - Würzburg
KW - Universitätsbibliothek
KW - Bericht
KW - Jahresbericht
KW - Würzburg
KW - University Library
KW - Report
KW - Annual Report
KW - Wuerzburg
KW - Wurzburg
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-42250
ER -
TY - JOUR
A1 - Heinsen, Helmut
A1 - Heinsen, Y. L.
T1 - Regionale Unterschiede der numerischen Purkinje-Zell-Dichte in Kleinhirnen von Albinoratten zweier Stämme
N2 - The total number and the number of Purkinje cells per square millimeter of the surface of the cerebellar granular layer were measured in albino rats from two strains: Chbb-THOM-Wist and Han: SPRD. The total number of the Purkinje cells in the cerebellar vermian lobules L land L X with the exception of cells in the lobules VIb + c did not. differ significantly. Statistically significant differences were found between the individuals of the two rat strains and within single lobules of the cerebella concerning the cell density of Purkinje cells per square millimeter surface of the granular layer. The results suggest heterogeneity of the cerebellar cortex between cerebellar lobules and between albino rats derived from different strains.
KW - Albinoratten
KW - Purkinje-Zellen
KW - Quantitative Anatomie
KW - Albino rats
KW - Purkinje cells
KW - Quantitative anatomy
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-45752
ER -
TY - CHAP
A1 - Ellgring, Johann Heinrich
T1 - Kommunikation
N2 - No abstract available
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-43006
ER -
TY - CHAP
A1 - Krüger, Hans-Peter
T1 - What differentiates a differential psychopharmacology?
N2 - The methodological implications of a differential psychopharmacology are discussed. It is shown that the technique of stratifying subjects with personality scores depends on one basic assumption: the personality score is not affected by the other experimental factors. Two experiments are reported in which pre- and posttest (after the experiment) scores were measured. The pre-post-differences showed themselves to be affected by the medication. It is argued that in psychopharmacological experimentation an additional step must be included. All non-treatment factors must be examined for their stability in the course of the experiment. If they are stable, usual evaluation may take place. If changes are attributable to the treatment, personality scores must be regarded as dependent variables. They have to be evaluated together with the other observables with a multivariate model. Additionally, a procedure like this yields as "experimental differential psychology" a self-reliant contribution to the problems of differential psychology.
KW - Differential psychopharmacology
KW - differential psychology
KW - drug-personality interaction
KW - methodology of differential psychopharmacology
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-41248
ER -
TY - JOUR
A1 - Christl, Manfred
A1 - Leininger, Hartmut
A1 - Mattauch, Brigitte
T1 - The 13C NMR Spectra of Some Tricyclo[2.2.0.02,6]hexane Derivatives : Unexpected High Field Absorptions Due to Additive gamma-anti Subsituent Effects
N2 - By means of the BC NMR spectra of tricyclo{2.2.0~rfJ6Jhexane and thirteen of its derivatives the effects of substituents in endo-3- and endo-5-positions on the HC chemical shifts have been determined. The y-anti effects are at least as Jarge as in monosubstituted cyc1obutanes, where the shielding values of second-row hetero substituents exceed those in unstrained systems by far, and higher-row and carbon substituents still cause substantial upfield shifts. In the title system the y-anti effect of a substituent in the endo-3- and endo-5-position are operative additively, and thus shift the absorption of C-J upfieJd by a maximum of 27 ppm with respect to the unsubstituted hydrocarbon.
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-41620
SN - x
ER -
TY - JOUR
A1 - Hommers, Wilfried
T1 - Subtraktive Hyperkonkavität in der funktionalen Beziehung von zukünftigem Wert und Zeitspanne bis zu seiner Auszahlung: Ein gruppenstatistischer Nachgesang als differentialpsychologischer Auftakt
N2 - Ziel der Untersuchung war die Prüfung der humanpsychologischen Validität von quantitativen neobehavioristischen Theorie~ über den Zusammenhang von 'Verten und Zeitspannen bis zu ihren Auszahlungen. Der sofort erforderliche Geldbetrag für den Verzicht auf eine zukünftige Geldauszahlung und der erforderliche zukünftige Geldbetrag für den Verzicht auf einen gegenwärtig verfügbaren Gcldbetrag war unter Variation der Geldbeträge und der Zeitspannen einzuschätzen. Als Ergebnis wurde varianzanalytisch unter Berücksichtigung der Utilität des Geldes eine subtraktive Beziehung zwischcn zukünftigem Geldbetrag und der Zeitspanne bis zu seiner Auszahlung bestimmt. In diese subtraktive Beziehung gingen die Geldbeträge und die Zeitspannen als Potenzfunktionen ein. Durch die Potenzfunktion der Zeit verläuft daher die Kurve des gegenwärtigen Wertes einer zukünftigen Auszahlung konkaver als die e-Funktion, so daß damit Vornahmeänderungen oder impulsive Reaktionen erklärt wer4a) and strong papaverine-like spasmolytics (4a ≈4b).
KW - antimuscarinic and papaverine-like activity
KW - sila-substitution
KW - crystal and molecular structure
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-128410
VL - 38
IS - 6
ER -
TY - JOUR
A1 - Tacke, Reinhold
A1 - Lange, Hartwig
A1 - Bentlage, Anke
A1 - Sheldrick, William S.
A1 - Ernst, Ludger
T1 - 2.2.5.5-Tetraorganyl-1.4-dioxa-2.5-disilacyclohexane/2,2,5,5-Tetraorganyl-1,4-dioxa-2,5-disilacyclohexanes
JF - Zeitschrift für Naturforschung B
N2 - The 2,2,5,5-tetraorganyl-1,4-dioxa-2,5-disilacyclohexanes 2a-2c were prepared by condensation of the corresponding (hydroxymethyl)diorganylsilanes 1 a-1 c. The constitution of the heterocycles was confirmed by elemental analyses, cryoscopic measurements, mass spectrometry, and NMR-spectroscopic \((^1H, ^{13}C)\) investigations. The molecular structure of 2 b was determined by X-ray diffraction analysis.
KW - 1,4-Dioxa-2
KW - 5-disila-cyclohexane ring system
KW - synthesis
KW - structure
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-128423
VL - 38
IS - 2
ER -
TY - JOUR
A1 - Wieber, M.
A1 - Wirth, D.
A1 - Burschka, Christian
T1 - Methyldixanthogenatostibane
N2 - Methyldixanthogenatostibane CH\(_3\)Sb(S\(_2\)COR)\(_2\) erhält man entweder durch Reaktion von Methyldibromstiban mit entsprechenden Natriumxanthogenaten bei tiefen Temperaturen (-78°C) oder durch Einschiebung von CS\(_2\) in Methyldialkoxistibane. Die Röntgenstrukturanalyse von CH\(_3\)Sb(S\(_2\)COC\(_2\)H\(_5\))\(_2\) zeigt, daß im Kristall die Chelatliganden das Antimonatom intraund intermolekular koordinieren, so daß eine pentagonal-pyramidale bzw. unter Einbezug des freien Elektronenpaars pentagonal-bipyramidale Koordination am Antimon vorliegt.
N2 - Methyldi:x:anthatostibanes CH\(_3\)Sb(S\(_2\)COR)\(_2\) are obtained either byreacting sodium xanthates with methyldibromostibanes at low temperatures (-78°0) or by insertion of CS\(_2\) in methyldialkoxistibanes. An X-ray analysis of CH\(_3\)Sb(S\(_2\)COC\(_2\)H\(_5\))\(_2\) is given. It shows that in the crystal the Sb atom is chelated fivefold - inter and intramolecular - by sulfur atoms, so that a pentagonal pyramidal or pentagonal bipyramidal, with inclusion the lone pair, geometry is observed.
KW - Chemie
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-31952
ER -
TY - JOUR
A1 - Hacker, Jörg
A1 - Knapp, S.
A1 - Goebel, W.
T1 - Spontaneous deletions and flanking regions of the chromosomal inherited hemolysin determinant of an Escherichia coli 06 strain
N2 - The hemolytic Escherichia coli strain 536 (06) propagates spontaneous hemolysin- negative mutants at relatively high rates (10-3 to 10-4 ). One type of mutant (type I) lacks both secreted (external) and periplasmic (internal) hemolysin activity (HlYex - IHlYin -) and in addition shows no mannose-resistant hemagglutination (Mrh -), whereas the other type (type II) is HlYex -IHIYin + and Mrh +. The genetic determinants for hemolysin production (hly) and for mannose-resistant hemagglutination (mrh) of this strain are located on the chromosome. Hybridization experiments with DNA probes specific for various parts of the hly determinant reveal that mutants of type I have lost the total hly determinant, whereas those of type 11 lack only part of the hlyB that is essential for transport of hemolysin across the outer membrane. Using a probe that contains the end sequence of the plasmid pHly152-encoded hly determinant (adjacent to hlyB), we determined that a related sequence flanks also the hlyB-distal end of the chromosomal hly determinant of E. coli 536. In addition several other similar or even identical sequences are found in the vicinity of the hlyC- and the hlyB-distal ends of both the chromosomal and the plasmid hly determinants.
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-40260
ER -
TY - JOUR
A1 - Burschka, Christian
A1 - Baumann, F.-E.
A1 - Schenk, W. A.
T1 - Schwefel(IV)-Verbindungen als Liganden. II. Die Kristall- und Molekülstruktur von Pentacarbonyl-(schwefeldioxid)chrom
T1 - Sulfur(IV) Compounds as Ligands. II. The Crystal and Molecular Structure of Pentacarbonyl-(sulfur dioxide)chromium
N2 - Die Struktur von Pentacarbonyl(schwefeldioxid)chrom (1) wurde röntgenographisch aus Einkristalldaten bestimmt. Die Verbindung kristallisiert mit acht Formeleinheiten in der rhombischen Elementarzelle (Raumgruppe Pbn2\(_1\)) folgender Dimensionen: a = 657,8(2) pm, b = 1245,2(4) pm, c = 2177,4(5) pm (bei 180 K). Das Schwefeldioxid ist \(\eta^1\)-koplanar koordiniert, der Cr-S-Abstand ist mit 219 pm der kürzeste bisher gefundene Abstand zwischen Chrom(O) und Schwefel. Die Cr-C(ax)-Bindung ist mit 189 pm fast genau so lang wie die Cr-C(eq).Bindungen (190 pm), ein Beleg für das hohe \(\pi\)-Akzeptorvermögen des S0\(_2\).
N2 - The structure of pentacarbonyl(sulfurdioxide)chromium (1) has been determined from single crystal X-ray data. The compound crystallizes with eight formula units in the rhombic unit cell (space group Pbn2\(_1\) ) of the dimensions a = 657.8(2) pm, b = 1245.2(4) pm, c = 2177.4(5) pm (at 180 K). The sulfur dioxide ia \(\eta^1\)-coplanar coordinated, the Cr-S distance is 219 pm, the shortest. bond reported so far between chromium(O) and sulfur. The Cr-C(ax) bond (189 pm) was found only marginally shorter than the Cr-C(eq) bonds (190 pm) providing proof of the high \(\pi\)·acceptor capacity of S0\(_2\)
KW - Chemie
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-31388
ER -
TY - JOUR
A1 - Lanzendörfer, Franz
A1 - Christl, Manfred
T1 - 3,4-Bismethylentricyclo[3.1.0.02,6]hexan - Synthese und Diels-Alder-Addition an Tetracyanethylen
N2 - No abstract available
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-30263
ER -
TY - JOUR
A1 - Christl, Manfred
A1 - Leininger, Hartmut
A1 - Brückner, Dieter
T1 - On the Nature of the Bicyclo [3.2.1]octa-3,6-dien-2-yl Anion: A 13C NMR spectroscopic study
N2 - No abstract available
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-30060
ER -
TY - JOUR
A1 - Scheer, Ulrich
A1 - Lanfranchi, Gerolamo
A1 - Rose, Kathleen M.
A1 - Franke, Werner W.
A1 - Ringertz, Nils R.
T1 - Migration of rat RNA polymerase I into chick erythrocyte nuclei undergoing reactivation in chick-rat heterokaryons
N2 - Transcriptionally inactive chick erythrocyte nudei were reactivated by Sendai virusinduced fusion of erythrocytes with rat L6j1 myoblasts. We used antibodies to trace the appearance of a specific protein engaged in transcription of a defined dass of genes, those coding for rRNA, during reactivation. Using immunofluorescence microscopy, we found increasing amounts of rat RNA polymerase I to appear, during a certain period of time after fusion, in the reforming nudeoli of the chick nudei. Amounts of rat RNA polymerase I sufficient to be detected by immunofluorescence microscopy had accumulated in the newly developed chick nudeoli 72- 190 h after fusion was initiated. This time interval coincides with the time when chick rRNA synthesis can first be detected. The results raise the possibility that during these stages of the reactivation process chick rRNA genes are transcribed by heterologous RNA polymerase I moleeules of rat origin.
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-33232
ER -
TY - JOUR
A1 - Tacke, Reinhold
A1 - Bentlage, Anke
A1 - Towart, Robertson
A1 - Möller, Eike
T1 - Sila-pharmaca, XXV. Sila-analogues of nifedipine-like dialkyl 2,6-dimethyl-4-aryl-1,4 dihydropyridine-3,5-dicarboxylates, III
N2 - IS neue C/Si-Analogenpaare (C-Verbindungen und sila- bzw. disila-substituierte Derivate), die sich strukturell vom Nifedipin ableiten, wurden synthetisiert. Diese und einige weitere C/Si-Paare wurden hinsichtlich ihrer physikochemischen und pharmakologischen Eigenschaften vergleichend untersucht. Mittels reversed-phase-Dünnschichtchromatographie wurde gezeigt, daß die Sila- bzw. Disila-Analoga lipophiler sind als die entsprechenden C-Verbindungen. Bezüglich der spasmolytischen in vitra-Aktivitäten zeigen die Si-Verbindungen in erster Näherung ähnliche Struktur-Wirkungs-Beziehungen wie ihre Carba-Analoga. Dagegen konnten hinsichtlich der ill vlva-Effekte (cardiovasculäre und antihypertensive Aktivität) in einigen Fällen große Unterschiede nachgewiesen werden.
N2 - 15 new C/Si-analogue pairs (C-compounds and sila- or disila-substituted derivatives, respectively), which are structurally related to nifedipine, have been synthesized. These and some further C/Si-pairs have been investigated comparatively with respect to their physicochemical and pharmacological properties. Using reversed-phase thin-layer chromatography it was shown that both the sila- and disila-analogues are more Iipophilic than the corresponding C-compounds. With respect to the in vitra spasmolytic potencies the Si-compounds show approximately similar structure-activity relationships to their carba-analogues. However, in some cases marked differences in in vivo effects (cardiovascular and antihypertensive activity) could be demonstrated.
KW - Anorganische Chemie
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-78357
ER -
TY - JOUR
A1 - Schneider, Wolfgang
A1 - Zielinski, Werner
T1 - Vergleichende Bedingungsanalysen zur Performanz guter und schwacher Rechtschreiber
T1 - A comparison of structural models describing and explaining spelling performance of good and poor spellers
N2 - Es wurde die Frage überprüft, ob für schwache Rechtschreiber und rechtschreibunauffällige Schüler ähnliche Determinanten der Rechtschreibleistung angenommen werden können. Theoretisch plausible Kausalmodelle zur Beschreibung und Erklärung von Rechtschreibleistungen rechtschreibschwacher und rechtschreibunauffälliger Viertkläßler wurden im Hinblick auf ihre Übereinstimmung und Datenkompabilität anhand des Computerprogramms LISREL IV analysiert. Für beide Gruppen ergaben sich unterschiedlich strukturierte Lösungen, von denen lediglich die für die normalen Rechtschreiber hinsichtlich der Datenanpassung und des Prozentsatzes aufgeklärter Kriteriumsvarianz einigermaßen befriedigen konnte.
N2 - In the present study, an attempt was made to simultaneously test causal models of spelling performance for two samples of fourth grade dyslexic children and normal speUers. The computer program LISREL IV was used to answer the question if the same structural model holds for both samples. Different solutions were obtained for both groups. While the models all showed an acceptable data fit, only the solution for the normal spellers explained enough criterion variance to be practically important.
KW - Rechtschreibschwäche
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-87297
ER -
TY - JOUR
A1 - Wilhelm, Gernot
T1 - Der hurritische Ablativ-Instrumentalis /ne/
N2 - No abstract available.
KW - Churritisch
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-87668
ER -
TY - BOOK
A1 - Wolf, Norbert Richard
A1 - Domröse, Gerd
A1 - Sprothen, Otmar
A1 - Wallraff, Dieter
A1 - Danner, Klaus
T1 - List Sprachbuch 7
N2 - No abstract available
KW - Deutschunterricht
KW - Lehrmittel
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-41703
ER -
TY - JOUR
A1 - Kleinschmidt, Jürgen A.
A1 - Scheer, Ulrich
A1 - Dabauvalle, Marie-Christine
A1 - Bustin, Michael
A1 - Franke, Werner W.
T1 - High mobility group proteins of amphibian oocytes: a large storage pool of a soluble high mobility group-1-like protein and involvement in transcriptional events
N2 - No abstract available
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-33250
ER -
TY - JOUR
A1 - Viebrock, A
A1 - Perz, A
A1 - Sebald, Walter
T1 - Molecular cloning of middle-abundant mRNAs from Neurospora crassa
N2 - no abstract available
KW - Neurospora crassa
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-82033
ER -
TY - BOOK
A1 - Wehgartner, Irma
T1 - Corpus Vasorum Antiquorum / Deutschland. 51. Würzburg, Martin-von-Wagner-Museum, 3
N2 - No abstract available.
KW - Römisches Reich
KW - Griechenland
KW - Vase
KW - Deutschland
KW - Museum
KW - Katalog
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-87547
ER -
TY - BOOK
A1 - Domröse, Gerd
A1 - Wolf, Norbert Richard
T1 - Deutschunterricht in der 5. und 6. Jahrgangsstufe: Lehrerhandbuch zu LIST Sprachbuch 5 und 6 und LIST Schülertraining Deutsch mit einem praxisbezogenen "Grundkurs" Grammatik
N2 - No abstract available
KW - Sprachunterricht / Deutschunterricht / Lehrerhandbuch
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-41710
SN - 3-471-22255-3
ER -
TY - JOUR
A1 - Schneider, Wolfgang
A1 - Scheibler, D.
T1 - Probleme und Möglichkeiten bei der Bewertung von Clusteranalyse-Verfahren: III. Appendix: Kurzbeschreibung der verbreitetsten Clusteranalyse-Algorithmen
T1 - On the evaluation of clustering algorithms, III. Appendix:
a description of the most popular algorithms
T1 - Problemeset cossibilites d'evaluation de procedes des analyses Cluster, III. Appendix: Courte description des Algorithmes analyse Cluster les plus rependues
N2 - Es wird eine relativ einfach gehaltene Kurzcharakteristik derjenigen Clusteranalyse-Algorithmen gegeben, die aufgrund eines Literaturüberblicks (SCHNEIDER & SCHEIBLER 1983a) als die in der Fonchung hauptsächlich benutzten Verfahren einzustufen sind. Die Kurzbeschreibung verzichtet im wesentlichen auf statistische Details und verfolgt speziell das Ziel, dem Leser eine Vorstellung von Gemeinsamkeiten und Untenchieden in der Funktionsweise von hierarchischen Clusteranalysen, Optimierungs- bzw. Partitionierungstechniken, Dichteverfahren, "Clumping Techniques" und anderen Prozeduren zu geben.
N2 - This paper presents a summary of 18 clustering algorithms most frequently applied in reseuch (cf. SCHNEIDER & SCHEIBLEK 1983a). Only a short description of each procedure is provided which aims at highlighting the basic differences and comrnonalities of hierarchical clustering algorithms, iterative partitioning methods, mode seeking techniques, clumping techniques, and other procedures.
N2 - Les Algorithmes analyse Cluster qui sont decritent par (Schneider & Scheibler 1983) comme etant les procedes les plus rependus dans Ia recherche sont relates ici de facon courte. Le description chematique exclue l'ennumeration des details statistiques et a pour but essentiel de transmettre au lecteur, entre autre, une representation des rapports et des differences dans Je mode de fonction des analyses Cluster hierarchiques, des techniques d'optimation, et des procedes de population «Clumping techniques» etc.
KW - Cluster-Analyse
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-69643
ER -
TY - JOUR
A1 - Schneider, Wolfgang
A1 - Scheibler, D.
T1 - Probleme und Möglichkeiten bei der Bewertung von Clusteranalyse-Verfahren: II. Ergebnisse einer Monte-Carlo-Studie
T1 - On the evaluation of clustering algorithms: A Monte Carlo approach
T1 - Probleme et possibilite pour l'evaluation des procedes l'analyse de cluster
N2 - Ziel der vorliegenden Untersuchung war es, Aufschluß über die unterschiedliche Qualität hierarchischer und nicht-hierarchischer (partionierender) Clusteranalyseverfahren zu gewinnen. Die Reproduktionsgüte beider Clusteranalyse-Varianten wurde anhand von 200 Monte-Carlo-Datensätzen (multivariat normalverteilte Mixturen) zu überprüfen versucht, wobei jeweils unterschiedliche Proportionen der Daten-Elemente klassifiZiert werden mußten. Es zeigte sich, daß insgesamt gesehen die hierarchischen Algorithmen nach WARD und LANCE-WILUAMS am besten dazu in der Lage waren, die vorgegebenen Datenstrukturen zu reproduzieren, andererseits aber die herangezogenen partitionierenden KMEANS-Verfahren nicht schlechter abschnitten, wenn die Lösung der WARD-Technik als Start-Partition vorgegeben wurde.
N2 - In this study, a number of hierarchical dustering algorithms and nonhierarchical (i.e. iterative-partitioning) methods were compared with regard to accuracy on the basis of 200 monte carlo data sets. As main results, the two hierarchical procedures by WARD and LANCE-WILUAMS as weil as two nonhierarchicallc-means algorithm using WARDs solution as starting seeds proved tobe most robust. Although some of the remaining algorithms showed acceptabel recovery values when only a certain proportion of the elements had to be classified, it is recommended to choose the few methods mentioned above for particular applications.
N2 - Le but de cette etude est d'obtenir des renseignements sur les differentes qualitees hierarchiques et non-hierarchiques (partionaires) procedes d'analyse de Clusters. Le qualite de reproduction des deux variantes d'analyse de Cluster a ete relevee et controlee a l'aide de 200 groupes de Monte-Cario (multivariation, melange de distribution normale). Pour chacune des proportions differentes, les elements de donnees ont du etre classes. On observe, dans l'ensemble, que l'algorithme hierarchique selon Ward etLance-Williams, est en mesure de reproduire, le mieux, les structures de donnees impliquees. D'autre part, les procedes appliques de KMEANS-partionaires ne se detachent pas pour le moins de ces resultats lorsque Ia solution de Ia technique de Ward a été, au prealablement, donnée comme situation de depart.
KW - Monte-Carlo-Simulation
KW - Cluster-Analyse
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-69637
ER -
TY - JOUR
A1 - Schneider, Wolfgang
A1 - Scheibler, D.
T1 - Probleme und Möglichkeiten bei der Bewertung von Clusteranalysen: I. Ein Überblick über einschlägige Evaluationsstudien
T1 - On the evaluation of dustering algorithms: An integrative review
T1 - Procédés de Cluster-analyse
N2 - Es wird ein Oberblick über Evaluationsstudien gegeben, die sich mit der Validität von Clusteranalyse-Algorithmen befassen. Im Anschluß an die Diskussion möglicher Bewertungskriterien werden Vergleichsuntersuchungen näher analysiert und danach geordnet, ob sie empirische Datensätze, Plasmaden oder Monte-Carlo-Datensätze als Evaluationsgrundlage benutzen. Die Obersicht über komplexer angelegte Monte-Carlo-Studien zeigt die unterschiedliche Qualität der verfügbaren Clusteranalyse-Algorithmen auf, macht andererseits aber auch deutlich, daß bestimmte hierarchisch-agglomerative Verfahren wie etwa die Methoden nachWARD oder LANCE-WILLIAMS bzw. iterativpartitionierende Prozeduren wie etwa die KMEANS-Algorithmen als relativ robuste Klassifikationsverfahren gelten können.
N2 - This paper presents a critical review of research on the evaluation of dustering algorithms. The review includes studies using empirical data sets and studies using so-called "plasmodes" (i. e., empirical data sets with known distributional parameters), but particularly concentrates on investigations using Monte-cario data sets. Although it turns out to be very difficult to come to a valid evaluation of the various clustering algorithms, hierarchical-agglomerative procedures like WARDsand LANCE-WILUAMs methods as well as the KMEANS algorithms appear to be most robust.
N2 - L'article suivant pn!sente une revue des etudes d'evaluation qui relevent de validite d'analyse de Cluster-Algorithme. Des experiences de comparaison sont analysees et classees a Ia Suite de la discution de criteres de jugement possible. Ceux-ci suivent un ordre donne par l'utilisation de donnees qui ont ete relevees empiriquement, «Plasmoden>> ou bien de donnees empiriquement accumulees selon Je principe d'evaluation de Monte-Carlo. La revue d'etude complexe Monte-Carlo montre Ia difference qualitative des analyses Cluster algorithme et, d'autre part met clairement en valeur, que des procedes hierarchiques-agglomeratifs, comme la methode de WARD ou LANCE-WILLIAMS, par exemple - c'est-a-dire des procedes «iteratif-partitionierende» {iteratif comme par exemple, les algorithmes KMEANS, qui peuvent etre consideres comme procedes de classification robuste.
KW - Cluster-Analyse
KW - Methode
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-87288
ER -
TY - CHAP
A1 - Hommers, Wilfried
T1 - Urteilsbildung : Entwicklung der Informationen-Integration im Urteil
N2 - No abstract available
KW - Psychologie
KW - Kongress
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-43497
ER -
TY - CHAP
A1 - Hommers, Wilfried
T1 - Zur quantitativen Theorie von Wiedergutmachungskognitionen unter Gewinnung ihrer Merkmale aus der Jurisprudenz
N2 - Grundzüge des rechtswissenschaftlichen Gedankenguts zur Schadenswiedergutmachung werden psychologischen Ansätzen dazu gegenübergestellt. Das Ergebnis ist die Feststellung, daß die stimulusbezogene Urteilsrelevanz der Schadenswiedergutmachung nicht in der psychologischen Forschung berücksichtigt wurde. Ein diesbezüglicher Untersuchungsansatz sollte sechs Merkmale besitzen: multifaktoriell, multivariat, Stimulus-Response-vergleichend, quantitativ, ontogenetisch und individual-diagnostisch. Er bildet den Prototyp eines die Moral positiver und negativer Akte umfassenden Ansatzes zur moralischen Urteilsbildung, des ses erste Ergebnisse beschrieben werden.
KW - Psychologie
KW - Kongress
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-43519
ER -
TY - BOOK
A1 - Hommers, Wilfried
T1 - Die Entwicklungspsychologie der Delikts- und Geschäftsfähigkeit : ein exemplarischer Beitrag zur Validität der zivilrechtlichen Altersgrenze des vollendeten siebenten Lebensjahres
N2 - No abstract available
KW - Deliktsfähigkeit
KW - Kind
KW - Geschäftsfähigkeit
KW - Entwicklungspsychologie
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-49189
SN - 3-8017-0195-6
ER -
TY - CHAP
A1 - Krüger, Hans-Peter
A1 - Kohnen, Ralf
T1 - Allgemeine Psychologie versus "Klinische Psychologie": eine plausible, aber unnötige Unterscheidung
N2 - Die Annahme, daß zwischen Allgemeiner und Klinischer Psychologie Unterschiede zu machen seien, wird an folgenden Schnittstellen kritisch hinterfragt: dem methodischen Zugang, dem Geltungsbereich ihrer Aussagen, ihren Inhalten, den untersuchten Populationen und speziellen Forschungsstrategien. Die Analyse einschlägiger Argumente fUhrt zu der Folgerung, daß Allgemeine Psychologie wie auch Klinische Psychologie ohne prinzipiellen Unterschied einer gemeinsamen Wissenschaft Psychologie zugehören. Grundbedingungen ftir die Wissenschaftlichkeit einer so verstandenen Einheitspsychologie werden an Beispielen aus der Wissenschaftspraxis erläutert. Ziel dieser Analyse ist es, eigenständige Forschungsarbeit der Klinischen Psychologie zu initiieren.
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-41291
SN - 3-466-35141-3
ER -
TY - JOUR
A1 - Wilhelm, Gernot
A1 - Meyer, Jan-Waalke
T1 - Eine spätbronzezeitliche Keilschrifturkunde aus Syrien (Tafeln 58a-59), 1. Der Text
N2 - No Abstract available
KW - Damaskus
KW - Archäologie
KW - Zeitschrift
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-85762
ER -
TY - CHAP
A1 - Wilhelm, Gernot
T1 - Die Keilschrifttafeln aus Kāmid el-Lōz
N2 - No abstract available.
KW - Kāmid el- Lōz
KW - Keilschrift
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-70366
ER -
TY - BOOK
A1 - Harth, Waltraud
T1 - Pauline Kergomard und die Entwicklung der Vorschulerziehung in Frankreich
N2 - No abstract available
KW - Kergomard
KW - Pauline / Vorschulerziehung
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-34201
SN - 3-88479-089-7
ER -
TY - CHAP
A1 - Wilhelm, Gernot
T1 - Reconstructing the phonology of dead languages
N2 - no Abstract available
KW - Schreiben
KW - Schrift
KW - Sprache
KW - Alphabetisierung
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-103601
ER -
TY - JOUR
A1 - Wagner, H.
A1 - Clarke, A. H.
A1 - Ellgring, Johann Heinrich
T1 - Eye-contact and individual looking - The role of chance
N2 - No abstract available
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-42078
ER -
TY - CHAP
A1 - Ellgring, Johann Heinrich
T1 - Spezifische Signalsysteme in der menschlichen Interaktion
N2 - Nonverbal communicative behaviours are associated with affective states in a way specific to the individual. This result emerged from longitudinal studies on depressed patients. From the analysis of various nonverbal behaviours it can be concluded that the depressed state is indicated by nonverbal elements in a logical "or-" rather than "and-connection" or in a hierarchical way. It is maintained that the relationship of psychological relevant states (mood) and nonverbal behaviour needs to be studied by intra-individual comparisons to reveal the specifically close relationships effective in everyday communication. With regard to the pragmatic aspect of communication, elements in the nonverbal signalling system seem to possess different levels of generality. However, from decoding studies it can be shown that even very subtle behavioural differences can be detected by an observer. Thus specific signals can become effective in interaction given a familiarity with the idiosyncratic usage.
KW - Psychologie
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-50212
ER -
TY - CHAP
A1 - Clarke, AH
A1 - Ellgring, Johann Heinrich
T1 - Computer-aided video
N2 - The recent developments in microprocessor electronics and time-code equipment have vastly improved the efficiency of working with video material so that through the combination of data processing and video recording equipment a substantial rationalization of both data acquisition procedures and functional control of the recording machines may be achieved. Such a system, in which video editing and time-code control equipment is interfaced to a process computer, has been developed for the analysis of human communicative behaviour. The system provides exact indexing of the recorded material, automatic search and edit routines for the videotape machines and synchronicity of registered data. In summary, it can be maintained that given a sound theoretical basis, modern video and computer technologies can substantially increase the efficiency and accuracy of behavioural observation and analysis.
KW - Psychologie
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-50332
ER -
TY - CHAP
A1 - Ellgring, Johann Heinrich
A1 - Clarke, AH
A1 - Wagner, H.
T1 - A syntactic approach to the analysis of nonverbal behaviour
N2 - No abstract available
KW - Psychologie
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-52403
ER -
TY - JOUR
A1 - Ruhe, Ernstpeter
T1 - Cet art bizarre. Adamovs Adaptionen für Theater, Rundfunk und Fernsehen.
N2 - No abstract available
KW - Adamov
KW - Arthur ; Kongress ; Würzburg <1981>
Y1 - 1983
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-32347
ER -