TY - JOUR A1 - Schartl, Manfred A1 - Barnekow, A. T1 - Differential expression of the cellular src gene during vertebrate development N2 - No abstract available KW - Physiologische Chemie Y1 - 1984 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-61893 ER - TY - JOUR A1 - Schartl, Manfred A1 - Barnekow, A. T1 - Cellular src gene product detected in the freshwater sponge Spongilla lacustris N2 - No abstract available KW - Physiologische Chemie Y1 - 1984 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-61904 ER - TY - JOUR A1 - Anders, F. A1 - Schartl., Manfred A1 - Barnekow, A. A1 - Anders, A. T1 - Xiphophorus as an in vivo model for studies on normal and defective control of oncogenes N2 - The Xiphophorus tumor system has provided the opportunity to reduce the enormous complexity of cancer etiology to a few biological elements basically involved in neoplasia. The development of a tumor requires an oncogene which, after impairment, deletion, or elimination of its regulatory genes is permitted to mediate neoplastic transformation. Emphasis is being placed today in cancer research on the actual oncogenes themselves, but, in our opinion, the most important genes involved in neoplasia are these regulatory genes. However, although detected by c1assical genetics in the Xiphophorus system, th ese genes are not at present open to a more fin ely detailed molecular biological analysis. Their actual mode of action is therefore still far from being understood. KW - Xiphophorus Y1 - 1984 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-80721 ER -