Fluorinated Aryl Boronates as Building Blocks in Organic Synthesis
Zitieren Sie bitte immer diese URN: urn:nbn:de:bvb:20-opus-225908
- Organoboron compounds are well known building blocks for many organic reactions. However, under basic conditions, polyfluorinated aryl boronic acid derivatives suffer from instability issues that are accelerated in compounds containing an ortho‐fluorine group, which result in the formation of the corresponding protodeboronation products. Therefore, a considerable amount of research has focused on novel methodologies to synthesize these valuable compounds while avoiding the protodeboronation issue. This review summarizes the latest developmentsOrganoboron compounds are well known building blocks for many organic reactions. However, under basic conditions, polyfluorinated aryl boronic acid derivatives suffer from instability issues that are accelerated in compounds containing an ortho‐fluorine group, which result in the formation of the corresponding protodeboronation products. Therefore, a considerable amount of research has focused on novel methodologies to synthesize these valuable compounds while avoiding the protodeboronation issue. This review summarizes the latest developments in the synthesis of fluorinated aryl boronic acid derivatives and their applications in cross‐coupling reactions and other transformations. image…
Autor(en): | Yudha P. Budiman, Stephen A. Westcott, Udo Radius, Todd B. Marder |
---|---|
URN: | urn:nbn:de:bvb:20-opus-225908 |
Dokumentart: | Artikel / Aufsatz in einer Zeitschrift |
Institute der Universität: | Fakultät für Chemie und Pharmazie / Institut für Anorganische Chemie |
Sprache der Veröffentlichung: | Englisch |
Titel des übergeordneten Werkes / der Zeitschrift (Englisch): | Advanced Synthesis & Catalysis |
Erscheinungsjahr: | 2021 |
Band / Jahrgang: | 363 |
Heft / Ausgabe: | 9 |
Erste Seite: | 2224 |
Letzte Seite: | 2255 |
Originalveröffentlichung / Quelle: | Advanced Synthesis & Catalysis 2021, 363(9):2224–2255. DOI: 10.1002/adsc.202001291 |
DOI: | https://doi.org/10.1002/adsc.202001291 |
Allgemeine fachliche Zuordnung (DDC-Klassifikation): | 5 Naturwissenschaften und Mathematik / 54 Chemie / 540 Chemie und zugeordnete Wissenschaften |
Freie Schlagwort(e): | boron reagents; boronates; fluorine; fluoroarene; homogeneous catalysis |
Datum der Freischaltung: | 14.10.2021 |
Lizenz (Deutsch): | CC BY: Creative-Commons-Lizenz: Namensnennung 4.0 International |