Refine
Has Fulltext
- yes (17)
Is part of the Bibliography
- yes (17)
Document Type
Language
- English (17)
Keywords
- Toxikologie (16)
- Adenosine receptors (5)
- Adenylate cyclase (4)
- barbiturates (2)
- rat brain membranes (2)
- (Rat brain membrane) (1)
- A1 (1)
- A1 adenosine receptors (1)
- A<sub>2</sub> Adenosine receptor (1)
- Adenosine receptor (1)
- Adenosine receptor antagonists (1)
- Adenosinrezeptor (1)
- Barbiturates (1)
- G-protein (1)
- GABA-receptor complex (1)
- Human platelets (1)
- N1E 115 cells (1)
- Pharmakologie (1)
- Phosphodiesterase (1)
- Radiation inactivation (1)
- Radioligand binding (1)
- Radioligands (1)
- Radioligauds (1)
- Target size (1)
- Xanthines (1)
- [3H]PIA binding (1)
- adenosine receptors (1)
- adenylate cyclase (1)
- agonists (1)
- radioligand binding (1)
- receptor solubilization (1)
- solubilization (1)
Institute
A\(_1\) adenosine receptors from different tissues and species we~e photoaffinity labelled and then the carbohydrate content was examined by both enzymatic and chemical treatment. Sodium dodecyl sulfate-polyacrylamide gel electrophoresis of the labelled membrane receptors shows that neuraminidase treatment alters the electrophoretic mobility of the receptor band indica ting the presence of terminal neurandnie acids. Neuraminidase digestion does not influence the binding characteristics of the receptor. The totally deglycosylated receptor protein obtained by chemical treatment has an apparent molecular weight Of 32,000.