Refine
Has Fulltext
- yes (9)
Is part of the Bibliography
- yes (9)
Document Type
- Journal article (9)
Language
- English (9)
Keywords
- 18F-FDG (1)
- 2- deoxy-2-(18F)fluoro-D-glucose (1)
- American Thyroid Association (1)
- Chernobyl (1)
- Combination (1)
- EBRT (1)
- Gehirn (1)
- German population (1)
- Insulin (1)
- Maus (1)
- Medizin (1)
- Medullärer Schilddrüsenkrebs (1)
- Meningioma (1)
- PRRT (1)
- Peptide receptor radionuclide therapy (1)
- Positronen-Emissions-Tomografie (1)
- Radiotherapy (1)
- Skelettmuskel (1)
- advanced stages (1)
- attention deficit/hyperactivity disorder (ADHD) (1)
- autoimmune thyroiditis (1)
- breast cancer (1)
- caudate nucleus (1)
- childhood and adolescence (1)
- children (1)
- diagnostic medical radiation exposure (1)
- differentiated thyroid cancer (1)
- differentiated thyroid carcinoma (1)
- dopamine transporter (DAT) (1)
- hypothyroidism (1)
- iodine-131 (1)
- long-term complications (1)
- medullary thyroid carcinoma (1)
- methylphenidate (1)
- nitrate and thyroid carcinogenesis (1)
- other radiation exposure (atomic bombing/nuclear accidents) (1)
- pediatric thyroid cancer after Chernobyl and Fukushima (1)
- positron emission tomography (1)
- prognosis (1)
- radioiodine therapy (1)
- responsivity (1)
- rising incidence of thyroid cancer (1)
- screening and overdiagnosis (1)
- second primary malignancy (1)
- single photon emission computed tomography (SPECT) (1)
- striatum (1)
- therapeutic medical radiation exposure (EBRT/ RAI) (1)
- thyroid (1)
- thyroid cancer (1)
- treatment (1)
- tyrosine kinase inhibitor (1)
- vandetanib (1)
- young females (1)
Institute
Sonstige beteiligte Institutionen
EU-Project number / Contract (GA) number
- 701983 (1)
Background: The American Thyroid Association (ATA) uses criteria to assess the risk for persistent disease in differentiated thyroid carcinoma (DTC) after radioiodine therapy (RAI). There are no data available showing that this classification can be adopted unadjusted by Germany. Aim: The aim of our study is to investigate whether the ATA classification can be applied to a German population for short-term prognosis. Furthermore, we investigated the influence of an age cutoff value. Methods: We retrospectively analyzed 121 patients who were referred to our tertiary referral center. Patients were classified into risk categories, and the therapy response was determined according to ATA. Results: A total of 73/83 (88%) ATA low-risk patients and 12/19 (63%) intermediate-risk patients showed an excellent response; 2/19 (11%) high-risk patients had a biochemical, and 6 (31%) had a structural incomplete response. Of all 39 patients ≥55 years, 84% had an excellent response. Using a cut off of 50 years, 50/62 (81%) of the older patients showed an excellent response. Conclusion: The ATA risk classification is able to estimate the response to RAI therapy in a German population. A shift from 55 to 50 years as an age cutoff value does not result in any relevant change in the treatment response.