Refine
Has Fulltext
- yes (4)
Is part of the Bibliography
- yes (4)
Document Type
- Journal article (4)
Language
- English (4)
Keywords
- alkaline phosphatase (1)
- anaplastic medulloblastoma (1)
- animal model (1)
- asfotase alfa (1)
- brain tumor (1)
- cancer stem cells (1)
- children (1)
- craniofacial orthodontics (1)
- deformational cranial asymmetry (1)
- group 3 (1)
- hypophosphatasia (1)
- infants with deformational plagiocephaly (DP) (1)
- orthotopic xenograft (1)
- osteomalacia (1)
- physical examination (1)
- positionalskull deformities (1)
- rare bone disease (1)
- rickets (1)
- subjective perception (1)
- three-dimensional (1)
- three-dimensional imaging (1)
Institute
- Neurochirurgische Klinik und Poliklinik (4)
- Kinderklinik und Poliklinik (2)
- Klinik und Poliklinik für Mund-, Kiefer- und Plastische Gesichtschirurgie (2)
- Institut für diagnostische und interventionelle Radiologie (Institut für Röntgendiagnostik) (1)
- Klinik und Poliklinik für Unfall-, Hand-, Plastische und Wiederherstellungschirurgie (Chirurgische Klinik II) (1)
- Lehrstuhl für Orthopädie (1)
- Medizinische Klinik und Poliklinik II (1)
- Pathologisches Institut (1)
- Poliklinik für Kieferorthopädie (1)
- Poliklinik für Zahnärztliche Prothetik (1)
Positional plagiocephaly (PP) is the most common skull deformity in infants. Different classification systems exist for graduating the degree of PP, but all of these systems are based on two-dimensional (2D) parameters. This limitation leads to several problems stemming from the fact that 2D parameters are used to classify the three-dimensional (3D) shape of the head. We therefore evaluate existing measurement parameters and validate a newly developed 3D parameter for quantifying PP. Additionally, we present a new classification of PP based on a 3D parameter. 210 patients with PP and 50 patients without PP were included in this study. Existing parameters (2D and 3D) and newly developed volume parameters based on a 3D stereophotogrammetry scan were validated using ROC curves. Additionally, thresholds for the new 3D parameter of a 3D asymmetry index were assessed. The volume parameter 3D asymmetry index quantifies PP equally as well as the gold standard of 30° diagonal difference. Moreover, a 3D asymmetry index allows for a 3D-based classification of PP. The 3D asymmetry index can be used to define the degree of PP. It is easily applicable in stereophotogrammetric datasets and allows for comparability both intra- and inter-individually as well as for scientific analysis.