Refine
Has Fulltext
- yes (32)
Is part of the Bibliography
- yes (32)
Year of publication
Document Type
- Doctoral Thesis (17)
- Journal article (14)
- Review (1)
Keywords
- rat (32) (remove)
Institute
- Institut für Virologie und Immunbiologie (7)
- Klinik und Poliklinik für Allgemein-, Viszeral-, Gefäß- und Kinderchirurgie (Chirurgische Klinik I) (4)
- Institut für Anatomie und Zellbiologie (3)
- Neurochirurgische Klinik und Poliklinik (3)
- Klinik und Poliklinik für Anästhesiologie (ab 2004) (2)
- Klinik und Poliklinik für Psychiatrie, Psychosomatik und Psychotherapie (2)
- Lehrstuhl für Tissue Engineering und Regenerative Medizin (2)
- Neurologische Klinik und Poliklinik (2)
- Pathologisches Institut (2)
- Graduate School of Life Sciences (1)
EU-Project number / Contract (GA) number
- 602133 (1)
- HEALTH-F2-2009-241778 (1)
Trichothecenes are mycotoxins which produce Iethai toxicosis in humans and animals, yet no adequate therapeutic regimen has been developed. This study provides evidence that the selective platelet activating factor (PAF) antagonist, BN 52021 (5-15 mg/kg i.v.) can prolong the survival of conscious rats exposed to a highly Iethai T -2 toxicosis. These data also suggest that P AF is an important mediator of this unique toxicosis.