Refine
Has Fulltext
- yes (15)
Is part of the Bibliography
- yes (15)
Document Type
- Journal article (14)
- Doctoral Thesis (1)
Keywords
- arthrography (3)
- magnetic resonance imaging (2)
- photon-counting (2)
- preclinical research (2)
- tomography (2)
- 3D-conformal radiotherapy (1)
- 3D-konformale Radiotherapie (1)
- CT angiography (1)
- Cancellous bone (1)
- Cone-beam computed tomography (1)
- Elbow (1)
- Elbow joint (1)
- Intensitätsmodulierte Radiotherapie (1)
- Multidetector computed tomography (1)
- Nicht-kleinzelliges Bronchialkarzinom (1)
- Strahlentherapie (1)
- X-ray computed (1)
- abdominal imaging (1)
- ankle (1)
- bone (1)
- bone bruise (1)
- bone marrow edema (1)
- bone remineralization (1)
- cancellous bone (1)
- cartilage (1)
- chiasma antebrachii (1)
- computed tomography (1)
- convolution kernel (1)
- dual-energy CT (1)
- dual-energy computed tomography (1)
- dual-source CT (1)
- experimental models of disease (1)
- femoral arteries (1)
- flexor digitorum superficialis (1)
- flexor tendon (1)
- fracture (1)
- fragility fracture (1)
- intensity modulated radiotherapy (1)
- joint instability (1)
- medical research (1)
- multiple myeloma (1)
- musculoskeletal system (1)
- obesity (1)
- photon-counting CT (1)
- photon-counting computed tomography (CT) (1)
- prestyloid recess (1)
- radiation dosage (1)
- radiation dose (1)
- small pixel effect (1)
- spectral CT (1)
- spectral shaping (1)
- tin prefiltration (1)
- translational research (1)
- triangular fibrocartilage (1)
- triangular fibrocartilage complex (1)
- ultra-low-dose CT (1)
- ultrahigh resolution (1)
- urinary calculi (1)
- virtual non-contrast (1)
- virtual noncalcium imaging (1)
- whole-body imaging (1)
- wrist (1)
- x-ray computed (1)
Institute
- Institut für diagnostische und interventionelle Radiologie (Institut für Röntgendiagnostik) (13)
- Institut für Anatomie und Zellbiologie (9)
- Klinik und Poliklinik für Allgemein-, Viszeral-, Gefäß- und Kinderchirurgie (Chirurgische Klinik I) (2)
- Klinik und Poliklinik für Strahlentherapie (2)
- Klinik und Poliklinik für Unfall-, Hand-, Plastische und Wiederherstellungschirurgie (Chirurgische Klinik II) (2)
- Lehrstuhl für Orthopädie (1)
- Medizinische Klinik und Poliklinik II (1)
This study evaluated the influence of different vascular reconstruction kernels on the image quality of CT angiographies of the lower extremity runoff using a 1st-generation photon-counting-detector CT (PCD-CT) compared with dose-matched examinations on a 3rd-generation energy-integrating-detector CT (EID-CT). Inducing continuous extracorporeal perfusion in a human cadaveric model, we performed CT angiographies of eight upper leg arterial runoffs with radiation dose-equivalent 120 kVp acquisition protocols (CTDIvol 5 mGy). Reconstructions were executed with different vascular kernels, matching the individual modulation transfer functions between scanners. Signal-to-noise-ratios (SNR) and contrast-to-noise-ratios (CNR) were computed to assess objective image quality. Six radiologists evaluated image quality subjectively using a forced-choice pairwise comparison tool. Interrater agreement was determined by calculating Kendall’s concordance coefficient (W). The intraluminal attenuation of PCD-CT images was significantly higher than of EID-CT (414.7 ± 27.3 HU vs. 329.3 ± 24.5 HU; p < 0.001). Using comparable kernels, image noise with PCD-CT was significantly lower than with EID-CT (p ≤ 0.044). Correspondingly, SNR and CNR were approximately twofold higher for PCD-CT (p < 0.001). Increasing the spatial frequency for PCD-CT reconstructions by one level resulted in similar metrics compared to EID-CT (CNRfat; EID-CT Bv49: 21.7 ± 3.7 versus PCD-CT Bv60: 21.4 ± 3.5). Overall image quality of PCD-CTA achieved ratings superior to EID-CTA irrespective of the used reconstruction kernels (best: PCD-CT Bv60; worst: EID-CT Bv40; p < 0.001). Interrater agreement was good (W = 0.78). Concluding, PCD-CT offers superior intraluminal attenuation, SNR, and CNR compared to EID-CT in angiographies of the upper leg arterial runoff. Combined with improved subjective image quality, PCD-CT facilitates the use of sharper convolution kernels and ultimately bears the potential of improved vascular structure assessability.