Refine
Has Fulltext
- yes (28)
Is part of the Bibliography
- yes (28)
Year of publication
Document Type
- Journal article (27)
- Doctoral Thesis (1)
Keywords
- ADHD (6)
- depression (4)
- bipolar disorder (3)
- mental health (3)
- pregnancy (3)
- BDNF (2)
- Bipolar disorder (2)
- antidepressant (2)
- anxiety (2)
- attention (2)
- hyperactivity (2)
- impulsivity (2)
- lactation (2)
- mental disorders (2)
- peripartum (2)
- polygenic risk score (2)
- systematic review (2)
- ADHD patients (1)
- Abelson helper integration-1 (AHI1) (1)
- Adult (1)
- Aggression (1)
- Alzheimers disease (1)
- Antisocial behavior (1)
- Arbeitsg (1)
- Association (1)
- Aufmerksamkeits-Defizit-Syndrom (1)
- Biomarke (1)
- C-reactive protein (1)
- COGITAT-Box (1)
- COVID-19 (1)
- Conduct disorder (1)
- Covid-19 (1)
- Cytokines (1)
- Deficit/hyperactivity disorder (1)
- Depression (1)
- Diagnostic approach (1)
- Dopamine Transporter (1)
- Dopaminstoffwechsel (1)
- Dopamintransporter (1)
- EBM (1)
- Elevated Plus Maze (1)
- Fibromyalgia syndrome (1)
- GHQ-28 (1)
- GRN (1)
- GWAS (1)
- Gene (1)
- Genotype (1)
- Inflammatio (1)
- Large multicenter ADHD (1)
- Maintenance treatment (1)
- Mania (1)
- Monopolar depression (1)
- NSSI (1)
- Nesplora Aquarium (1)
- Nitric oxide (1)
- Nitric oxide synthase (1)
- Opioid receptor (1)
- PARK2 (1)
- Polarity index (1)
- Predominant polarity (1)
- Qb-Test (1)
- Rating scale (1)
- Schizophrenie (1)
- Serotonin (1)
- Serotonine transporter (1)
- Serotonintransporter (1)
- Skin biopsy (1)
- Stickstoffmonoxid (1)
- Stickstoffmonoxid-Synthase (1)
- Stickstoffoxidsynthase (1)
- Susceptibility loci (1)
- UPPS (1)
- accidents (1)
- adolescence (1)
- adult attention deficit/hyperactivity disorder (adult ADHD) (1)
- age (1)
- antidepressants (1)
- anxious depression (1)
- association (1)
- astrocytes (1)
- attention deficit hyperactivity disorder (1)
- breast cancer (1)
- ceramides (1)
- child development (1)
- clinical practice guideline (1)
- cognitive deficits (1)
- cohort studies (1)
- continuous performance test (1)
- cortical activation (1)
- cross-sectional studies (1)
- cross-sectional study (1)
- dementia (1)
- depressive disorder (1)
- disease modelling (1)
- early recognition (1)
- emotion regulation (1)
- endocannabinoids (1)
- fNIRS (1)
- families (1)
- family caregivers (1)
- fibromyalgia syndrome (1)
- frontotemporal lobar degeneration (1)
- gene (1)
- gene ADGRL3 (1)
- geneexpression (1)
- genetic phenotypes (1)
- genome-wide association (1)
- glia (1)
- hiPSC (1)
- iPSCs (1)
- illness (1)
- incidence (1)
- induced pluripotent stem cells (1)
- informal caregiving (1)
- linkage (1)
- lithium (1)
- longitudinal studies (1)
- major depression (1)
- mapping susceptibility genes (1)
- maternal (1)
- mechanismofaction (1)
- mental illness (1)
- mitochondria (1)
- monoamine transporters (1)
- mood disorders (1)
- morality (1)
- mutation (1)
- near-infrared spectroscopy (1)
- neuropsychology (1)
- nitricoxidesynthase (1)
- non-suicidal self-injury (1)
- observer agreement (1)
- onset (1)
- pain (1)
- paternal (1)
- people (1)
- pharmacotherapy (1)
- physical health (1)
- population-based studies (1)
- postnatal depression (1)
- prefrontal cortex (1)
- prevalence (1)
- prevention (1)
- prophylactic lithium (1)
- psychological distress (1)
- psychosocial stress (1)
- psychotropic medication (1)
- psychotropic medications (1)
- reliability (1)
- remitted/acute phase (1)
- risk SNP rs1397547 (1)
- risk genes (1)
- self-employed (1)
- small business (1)
- stress (1)
- substance abuse disorder (1)
- tandem mass spectrometry (1)
- therapy response (1)
- universal prevention (1)
- venturesomeness (1)
- verbal n-back (1)
Institute
- Klinik und Poliklinik für Psychiatrie, Psychosomatik und Psychotherapie (26)
- Frauenklinik und Poliklinik (2)
- Institut für Klinische Epidemiologie und Biometrie (2)
- Klinik und Poliklinik für Kinder- und Jugendpsychiatrie, Psychosomatik und Psychotherapie (2)
- Lehrstuhl für Molekulare Psychiatrie (2)
- Neurologische Klinik und Poliklinik (2)
- Deutsches Zentrum für Herzinsuffizienz (DZHI) (1)
- Institut für Psychologie (1)
Sonstige beteiligte Institutionen
Single nucleotide polymorphisms (SNPs) in the ADGRL3 gene have been significantly associated with the development of ADHD, the aetiology of which remains poorly understood. The rs1397547 SNP has additionally been associated with significantly altered ADGRL3 transcription. We therefore generated iPSCs from two wild type ADHD patients, and two ADHD patients heterozygous for the risk SNP. With this resource we aim to facilitate further investigation into the complex and heterogenous pathology of ADHD. Furthermore, we demonstrate the feasibility of using magnetic activated cell sorting to allow the unbiased selection of fully reprogrammed iPSCs.