Refine
Has Fulltext
- yes (129)
Is part of the Bibliography
- yes (129)
Year of publication
Document Type
- Journal article (115)
- Conference Proceeding (9)
- Book article / Book chapter (5)
Keywords
- Physiologische Chemie (43)
- Schwertkärpfling (18)
- Xiphophorus (5)
- evolution (5)
- melanoma (5)
- Krebs <Medizin> (4)
- Onkogen (4)
- Tumor (4)
- medaka (4)
- Gen (3)
- Lebendgebärende Zahnkarpfen (3)
- Protein-Tyrosin-Kinasen (3)
- genome (3)
- meiosis (3)
- sex chromosomes (3)
- transcriptome (3)
- Biologie (2)
- DM-domain gene (2)
- DNS (2)
- Entstehung (2)
- Fingerprint-Verfahren (2)
- Fische (2)
- In vivo (2)
- Japankärpfling (2)
- Melanom (2)
- Umweltfaktor (2)
- Y chromosome (2)
- cancer (2)
- developmental biology (2)
- fish (2)
- fish model (2)
- gametogenesis (2)
- gene expression (2)
- genome annotation (2)
- microRNA (2)
- parthenogenesis (2)
- piRNA (2)
- preexisting bias (2)
- recombination (2)
- reproductive success (2)
- sequence alignment (2)
- sex determination (2)
- sex differentiation (2)
- sexual selection (2)
- synaptonemal complex (2)
- testis (2)
- transposable elements (2)
- zebrafish (2)
- 5-methylcytosine (1)
- Acipenser baerii (1)
- Amazon Molly (1)
- Annotation (1)
- Aulonocara (1)
- BMP signaling (1)
- Biology (1)
- Buntbarsche (1)
- Carcinogenese (1)
- Cell-line (1)
- Co-option (1)
- Coahuila (1)
- CrossQuery (1)
- Cynoglossus semilaevis (1)
- DMRT1 (1)
- DNA fingerprinting (1)
- DNA-binding proteins (1)
- Danio-rerio (1)
- Dmrt1bY (1)
- Drosophila melanogaster (1)
- Egfr (1)
- Embryo (1)
- Embryonalentwicklung (1)
- Enhancer (1)
- Epidermaler Wachstumsfaktor-Rezeptor (1)
- Eukaryoten (1)
- Fish (1)
- Freeze-etching (1)
- Gene expression analysis (1)
- Genetik (1)
- Genome (1)
- Genome assembly (1)
- Genome comparison (1)
- Genomics (1)
- Gentransfer (1)
- Germline (1)
- Gewebe (1)
- Goldbrasse (1)
- Human (1)
- Humangenetik (1)
- In vitro (1)
- Isoenzym (1)
- Jmjd6 (1)
- Karyotyp (1)
- Konservierung (1)
- Krebsforschung (1)
- Latimeria menadoensis (1)
- Ligand <Biochemie> (1)
- Male intromittent organ (1)
- Malignant melanoma (1)
- Mc4r (1)
- Medaka - Genetransfer - Transient expression - DNA fate - Fish developmental biology (1)
- Medizin (1)
- Megalobrama amblycephala (1)
- Melanoma (1)
- Messenger-RNS (1)
- Microarray data (1)
- Modell (1)
- Molekularbiologie (1)
- NGS (1)
- Nervenzelle (1)
- Niedere Wirbeltiere (1)
- Njassasee (1)
- PCR (1)
- PI3K (1)
- Pain (1)
- Perugia-Kärpfling (1)
- Pigmentmuster (1)
- Poecilia (Teleostei: Poeciliidae) (1)
- Poeciliid fish (1)
- Promotor (1)
- Protoonkogen (1)
- Protopterus annectens (1)
- RAS (1)
- RNA-SEQ data (1)
- RNA-Seq (1)
- RNA-seq transcriptome (1)
- RT -PCR (1)
- RTK (1)
- Recombinant DNA ; Growth hormone gene ; PCR; Silver carp ; Fish (1)
- Recombinant DNA ; polymerase chain reaction ; metallothionein gene ; rainbow trout ; fish (1)
- SGNH hydrolase (1)
- SMAD signaling (1)
- SOX9 (1)
- Schwertkräpfling (1)
- Sex chromosome (1)
- Sex determination (1)
- Sexual development and function (1)
- Single nucleotide change (1)
- Somatotropin (1)
- Sox5 (1)
- Sparus aurata (1)
- Spongilla lacustris (1)
- Sprouting angiogenesis (1)
- Squalius alburnoides (1)
- Synaptische Vesikel (1)
- Synaptophysin (1)
- Süßwasserpolypen (1)
- Transcription (1)
- Transcriptomic (1)
- Transgene Tiere (1)
- Transmission electron microscopy (1)
- Transposable element (1)
- Tumorzelle (1)
- Ultrastruktur (1)
- Veracruz <Stadt> (1)
- Wachstum (1)
- X. couchianus (1)
- X. hellerii (1)
- Xiphophorus fish (1)
- Y chromosome degeneration (1)
- Zebrafish (1)
- achiasmatic (1)
- acipenserid minisatellite (1)
- adaptive evolution (1)
- adaptive radiation (1)
- all-fish genes (1)
- amphimixis (1)
- androgen-induced masculinization (1)
- apomixis (1)
- automixis (1)
- beetle horns (1)
- cancer genomics (1)
- cancer models (1)
- cell fusion (1)
- cell proliferation (1)
- cellline transfection (1)
- chain reaction (1)
- chemotherapy resistance (1)
- chimera formation (1)
- chimeric RTKs (1)
- coloration (1)
- comparative genomics (1)
- contributes (1)
- copy-number alteration (1)
- crossing-over (1)
- crosstalk (1)
- cultures (1)
- determination locus (1)
- determining genes (1)
- deuterostomes (1)
- differentiation (1)
- dimorphic expression (1)
- divergent expression regulation (1)
- drug selection (1)
- embryonic stem-cells (1)
- energy homeostasis (1)
- epidermal growth factor receptor (1)
- evolutionary genetics (1)
- evolutionary mutant model (1)
- exaptation (1)
- expression (1)
- expression analysis (1)
- factor acetylhydrolase activity (1)
- fishes Xiphophorus (1)
- gene (1)
- gene duplications (1)
- gene prediction (1)
- gene regulatory network evolution (1)
- generation (1)
- genetic markers (1)
- genetic oscillators (1)
- genome assembly (1)
- genome cells (1)
- genomic organization (1)
- genomics (1)
- genus Xiphophorus (1)
- gonadal development (1)
- gonopodium (1)
- growth (1)
- growth hormone gene (1)
- gut microflora (1)
- gynogeaesls (1)
- gynogenesis (1)
- helitron (1)
- herbivorous diet (1)
- heterochromatin (1)
- heterogamety (1)
- human genomics (1)
- hybrid origin (1)
- hybridogenesis (1)
- in-vitro (1)
- intermuscular bone (1)
- introgressive hybridization (1)
- key innovation (1)
- kinase inhibitors (1)
- knockout (1)
- likelihood approach (1)
- linkage map (1)
- luciferase (1)
- lungfish (1)
- male size polymorphism (1)
- male-specific traits (1)
- malignant tumors (1)
- master sex-determining gene (1)
- medaka fish (1)
- medakafish oryzias latipes (1)
- melanogenesis (1)
- metastatic melanoma (1)
- miR-146a (1)
- miR-193a (1)
- mini-exon (1)
- mitochondrial DNA (1)
- mitochondrial genome (1)
- molecular biology (1)
- molecular mechanisms (1)
- molecular phylogeny (1)
- monodelphis domestica (1)
- mouse (1)
- mouse testis differentiation (1)
- mullerian hormone AMH (1)
- natural variation (1)
- oogenesis (1)
- oreochromis niloticus (1)
- oryzias latipes (1)
- oryzias-latipes (1)
- ovary (1)
- paralogs (1)
- parten-offspring conflict (1)
- pigment pattern (1)
- platelet activation factor (1)
- platyfish (1)
- pluripotency (1)
- poeciliid fishes (1)
- poeciliidae (1)
- polymerase (1)
- polyploidy (1)
- pp6oc-src (1)
- puberty (1)
- ras (1)
- receptor tyrosine kinase (1)
- regulatory regions (1)
- reproductive character displacement (1)
- retinoic acid (1)
- retrotransposons (1)
- rolling-circle transposons (1)
- sarcopterygian fish (1)
- satellite DNA (1)
- sex chromosome evolution (1)
- sex combs (1)
- sex linked pigmentation pattern (1)
- sex-determining region (1)
- sexual antagonistic genes (1)
- sexual conflict (1)
- sexually antagonistic genes (1)
- simple repeat sequences (1)
- simple repetitive sequences (1)
- size polymorpbism (1)
- small RNA-sequencing (1)
- sodal domlnance (1)
- species diversification (1)
- spermatogenesis (1)
- squalius alburnoides (1)
- stage III (1)
- sturgeon (1)
- sturgeon karyotype (1)
- swordtails (1)
- tandem repeats (1)
- teleost fish (1)
- teleost fishes (1)
- teleost flsh (1)
- teleostei (1)
- testosterone (1)
- topminnow (1)
- transcriptional rewiring (1)
- transgenic fish (1)
- transplantation (1)
- transposition (1)
- tree selection (1)
- variant detection (1)
- vertebrates (1)
- whole genome (1)
- whole genome duplication (1)
- whole genome duplications (1)
- whole-genome duplication (1)
- whole-genome sequencing (1)
- xiphophorus maculatus (1)
Institute
- Theodor-Boveri-Institut für Biowissenschaften (129) (remove)
Unisexual reproduction, which generates clonal offspring, is an alternative strategy to sexual breeding and occurs even in vertebrates. A wide range of non-sexual reproductive modes have been described, and one of the least understood questions is how such pathways emerged and how they mechanistically proceed. The Amazon molly, Poecilia formosa, needs sperm from males of related species to trigger the parthenogenetic development of diploid eggs. However, the mechanism, of how the unreduced female gametes are produced, remains unclear. Cytological analyses revealed that the chromosomes of primary oocytes initiate pachytene but do not proceed to bivalent formation and meiotic crossovers. Comparing ovary transcriptomes of P. formosa and its sexual parental species revealed expression levels of meiosis-specific genes deviating from P. mexicana but not from P. latipinna. Furthermore, several meiosis genes show biased expression towards one of the two alleles from the parental genomes. We infer from our data that in the Amazon molly diploid oocytes are generated by apomixis due to a failure in the synapsis of homologous chromosomes. The fact that this failure is not reflected in the differential expression of known meiosis genes suggests the underlying molecular mechanism may be dysregulation on the protein level or misexpression of a so far unknown meiosis gene, and/or hybrid dysgenesis because of compromised interaction of proteins from diverged genomes.