Filtern
Volltext vorhanden
- ja (4)
Gehört zur Bibliographie
- ja (4)
Dokumenttyp
Sprache
- Englisch (4) (entfernen)
Schlagworte
- CEA (1)
- CEACAM1 (1)
- LPS (1)
- PP2A (1)
- aging (1)
- angiogenesis (1)
- anti‐aging (1)
- bone marrow-derived monocytes (1)
- cancer (1)
- cytokines (1)
- heart (1)
- inflammation (1)
- ischemia (1)
- macrophages (1)
- malignancy (1)
- metastasis (1)
- mouse (1)
- protein phosphorylation (1)
- reactive oxygen species (1)
- sepsis (1)
- signaling (1)
- transgenic mice (1)
- tumor (1)
Institut
The Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1), also known as CD66a, is a member of the immunoglobulin superfamily. CEACAM1 was shown to be a prognostic marker in patients suffering from cancer. In this review, we summarize pre-clinical and clinical evidence linking CEACAM1 to tumorigenicity and cancer progression. Furthermore, we discuss potential CEACAM1-based mechanisms that may affect cancer biology.