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- Abszision (1)
- Caenorhabditis elegans (1)
- LC3-associated phagocytosis (1)
- Phagozytose (1)
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- ZF1 degradation assay (1)
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- midbody remnant (1)
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Abscission marks the last step of cytokinesis and gives rise to two physically separated daughter cells and a midbody remnant. This work studies abscission by examining the extent of the abscission failure in C. elegans septin and ESCRT mutants with the help of the ZF1-degradation technique. The ZF1 technique is also applied to discern a possible role for PI3K during abscission. Lastly, we test the role of proteins required for macroautophagy but not for LC3-associated phagocytosis (LAP) and show that after release into the extracellular space, the midbody is resolved via LAP.