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- Antigen CD28 (1)
- CD28 (1)
- CD28 Molekül (1)
- CD28 Superagonist (1)
- CD28 costimulation (1)
- CD28 superagonists (1)
- CD4\(^{+}\) T helper cells (1)
- D665 (1)
- Immunologie (1)
- Immunreaktion (1)
Like human Th1 cells, mouse Th1 cells also secrete IFN‐γ upon stimulation with a superagonistic anti‐CD28 monoclonal antibody (CD28‐SA). Crosslinking of the CD28‐SA via FcR and CD40‐CD40L interactions greatly increased IFN‐γ release. Our data stress the utility of the mouse as a model organism for immune responses in humans.