• Contact
    • Imprint
    • Sitemap
      • Deutsch

UNIWUE UBWUE Universitätsbibliothek

  • Home
  • Search
  • Browse
  • Publish
  • Help
Schließen

Refine

Keywords

  • X-ray (1)
  • conformational anaylses (1)
  • curare-lik activity (1)
  • silicon compounds (1)
  • structure-activity relationships (1)

Author

  • Attar-Bashi, Moayad T. (1)
  • Ernst, Ludger (1)
  • Frohnecke, Joachim (1)
  • Linoh, Haryanto (1)
  • Niedner, Roland (1)
  • Sheldrick, William S. (1)
  • Tacke, Reinhold (1)

1 search hit

  • 1 to 1
  • BibTeX
  • CSV
  • RIS
  • XML
  • 10
  • 20
  • 50
  • 100
Sila-Pharmaka, 26. Mitt. [1] Darstellung und Eigenschaften potentiell curarewirksamer Silicium-Verbindungen, III (1982)
Tacke, Reinhold ; Linoh, Haryanto ; Attar-Bashi, Moayad T. ; Sheldrick, William S. ; Ernst, Ludger ; Niedner, Roland ; Frohnecke, Joachim
The potentially curare-like silicon compounds 8a- 8f were synthesized and investigated with respect to their structure-activity relationships. The conformations of the compounds in the solid state and in solution were studied by X-ray diffraction analysis (8a- 8e) and IR NMR spectroscopy (8a- 8f), respectively. The muscle relaxing properties of 8a- 8f were investigated on the mouse. The observed structure-activity relationships are not in accordance with the classical "14 Å model" for neuromuscular blocking agents.
  • 1 to 1

DINI-Zertifikat     OPUS4 Logo