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  • Osteogeneration (1) (remove)

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  • Ernestus, Ralf I. (1)
  • Kessler, Almuth F. (1)
  • Linsenmann, Thomas (1)
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  • Westermaier, Thomas (1)

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Bone chips, fibrin glue, and osteogeneration following lateral suboccipital craniectomy: a case report (2013)
Linsenmann, Thomas ; Monoranu, Camelia M. ; Kessler, Almuth F. ; Ernestus, Ralf I. ; Westermaier, Thomas
Background Suboccipital craniectomy is a conventional approach for exploring cerebellopontine angle lesions. A variety of techniques have been successfully employed to reconstruct a craniectomy. This is the first report about the histological findings after performing a cranioplasty by using a mixture of autologous bone chips and human allogenic fibrin glue. Case presentation A 53-year-old German woman underwent left lateral suboccipital retrosigmoidal craniectomy for treatment of trigeminal neuralgia in 2008. Cranioplasty was perfomed by using a mixture of autologous bone chips and human allogenic fibrin glue. Due to recurrent neuralgia, a second left lateral suboccipital craniectomy was performed in 2012. The intraoperative findings revealed a complete ossification of the former craniotomy including widely mature trabecular bone tissue in the histological examination. Conclusion A mixture of autologous bone chips and human allogenic fibrin glue seems to provide sufficient bone-regeneration revealed by histological and neuroradiological examinations.
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