• Contact
    • Imprint
    • Sitemap
      • Deutsch

UNIWUE UBWUE Universitätsbibliothek

  • Home
  • Search
  • Browse
  • Publish
  • Help
Schließen

Refine

Has Fulltext

  • yes (1)

Is part of the Bibliography

  • yes (1)

Year of publication

  • 1985 (1)

Document Type

  • Journal article (1)

Language

  • English (1)

Keywords

  • Carcinogenesis (1)
  • DNA (1)
  • Toxikologie (1)
  • aflatoxin (1)
  • covalent binding (1)
  • ethanol (1)

Author

  • Lutz, Werner K. (1)
  • Marinovich, M. (1)

Institute

  • Institut für Pharmakologie und Toxikologie (1)

1 search hit

  • 1 to 1
  • BibTeX
  • CSV
  • RIS
  • XML
  • 10
  • 20
  • 50
  • 100
Covalent binding of aflatoxin B\(_1\) to liver DNA in rats pretreated with ethanol (1985)
Marinovich, M. ; Lutz, Werner K.
Male Fischer F-344 rats were given ethanol in the drinking water and/or by single oral administration. Following this, the animals received p.o. 100 ng/kg of the hepatocarcinogen eHJaflatoxin BI (AFBI)' 24 h later, the level of DNA-bound AFBI was determined in the liver and was found not to be affected by any type of ethanol pretreatment. A cocarcinogenic effect of ethanol in the liver is therefore unlikely to be due to an effect on the metabolic activation and inactivation processes governing the formation of DNA-binding AFBI metabolites.
  • 1 to 1

DINI-Zertifikat     OPUS4 Logo