• Deutsch
  • Home
  • Search
  • Browse
  • Publish
  • Help
Schließen

Refine

Has Fulltext

  • yes (1)

Is part of the Bibliography

  • yes (1)

Year of publication

  • 2020 (1)

Document Type

  • Journal article (1)

Language

  • English (1)

Keywords

  • breastfeeding (1)
  • inattention/hyperactivity (1)
  • intelligence (1)
  • preterm children (1)
  • probiotic prophylaxis (1)
  • strength and difficulties (1)

Author

  • Astiz, Mariana (1)
  • Banaschewski, Tobias (1)
  • Fortmann, Ingmar (1)
  • Göpel, Wolfgang (1)
  • Herting, Egbert (1)
  • Härtel, Christoph (1)
  • Keil, Thomas (1)
  • Oster, Henrik (1)
  • Romanos, Marcel (1)
  • Siller, Bastian (1)
+ more

Institute

  • Institut für Klinische Epidemiologie und Biometrie (1)
  • Kinderklinik und Poliklinik (1)
  • Klinik und Poliklinik für Kinder- und Jugendpsychiatrie, Psychosomatik und Psychotherapie (1)

1 search hit

  • 1 to 1
  • BibTeX
  • CSV
  • RIS
  • XML
  • 10
  • 20
  • 50
  • 100
Breastfeeding for 3 months or longer but not probiotics is associated with reduced risk for inattention/hyperactivity and conduct problems in very-low-birth-weight children at early primary school age (2020)
Härtel, Christoph ; Spiegler, Juliane ; Fortmann, Ingmar ; Astiz, Mariana ; Oster, Henrik ; Siller, Bastian ; Viemann, Dorothee ; Keil, Thomas ; Banaschewski, Tobias ; Romanos, Marcel ; Herting, Egbert ; Göpel, Wolfgang
(1) Background: We aimed to evaluate the effect of proposed “microbiome-stabilising interventions”, i.e., breastfeeding for ≥3 months and prophylactic use of Lactobacillus acidophilus/ Bifidobacterium infantis probiotics on neurocognitive and behavioral outcomes of very-low-birthweight (VLBW) children aged 5–6 years. (2) Methods: We performed a 5-year-follow-up assessment including a strength and difficulties questionnaire (SDQ) and an intelligence quotient (IQ) assessment using the Wechsler Preschool and Primary Scale of Intelligence (WPPSI)-III test in preterm children previously enrolled in the German Neonatal Network (GNN). The analysis was restricted to children exposed to antenatal corticosteroids and postnatal antibiotics. (3) Results: 2467 primary school-aged children fulfilled the inclusion criteria. In multivariable linear regression models breastfeeding ≥3 months was associated with lower conduct disorders (B (95% confidence intervals (CI)): −0.25 (−0.47 to −0.03)) and inattention/hyperactivity (−0.46 (−0.81 to −0.10)) as measured by SDQ. Probiotic treatment during the neonatal period had no effect on SDQ scores or intelligence. (4) Conclusions: Prolonged breastfeeding of highly vulnerable infants may promote their mental health later in childhood, particularly by reducing risk for inattention/hyperactivity and conduct disorders. Future studies need to disentangle the underlying mechanisms during a critical time frame of development.
  • 1 to 1

DINI-Zertifikat     OPUS4 Logo

  • Contact
  • |
  • Imprint
  • |
  • Sitemap