Refine
Has Fulltext
- yes (30)
Is part of the Bibliography
- yes (30)
Year of publication
- 2018 (30) (remove)
Document Type
- Journal article (22)
- Preprint (5)
- Conference Proceeding (3)
Language
- English (30)
Keywords
- Positronen-Emissions-Tomografie (16)
- PET (14)
- positron emission tomography (9)
- SPECT (5)
- neuroendocrine tumor (5)
- 18F-DCFPyL (3)
- 18F-FDG (3)
- DaTscan (3)
- PET/CT (3)
- RADS (3)
- SSTR (3)
- ageing (3)
- prostate cancer (3)
- theranostics (3)
- 11C-HED (2)
- 123I-mIBG (2)
- 123I-metaiodobenzylguanidine (2)
- 18F-LMI1195 (2)
- Ioflupane (2)
- PRRT (2)
- PSMA-PET (2)
- Parkinson (2)
- Parkinson Disease (2)
- Parkinson-Krankheit (2)
- Positron Emission Tomography (2)
- Prostate Cancer (2)
- Stammzelle (2)
- Virchow Node (2)
- [177Lu]-DOTATATE/-DOTATOC (2)
- [68Ga] (2)
- cardiomyocytes (2)
- fatty acid (2)
- hiPSC-CM (2)
- induced pluripotent stem cells (2)
- medullary thyroid carcinoma (2)
- molecular imaging (2)
- myocardial sympathetic innervation imaging (2)
- personalized medicine (2)
- personalized treatment (2)
- precision medicine (2)
- somatostatin receptor (2)
- stem cell therapy (2)
- tracer (2)
- tumor heterogeneity (2)
- tyrosine kinase inhibitor (2)
- vandetanib (2)
- 11C-Hydroxyephedrine (1)
- 11C-hydroxyephedrine (1)
- 123I-Ioflupane (1)
- 18F-FDS (1)
- 18F-flurpiridaz (1)
- 18FFBnTP (1)
- 2- deoxy-2-(18F)fluoro-D-glucose (1)
- 2-deoxy-2-(18F)fluoro-D-glucose (1)
- 68Ga-DOTATATE/-TOC (1)
- 99mTc-DTPA (1)
- AI (1)
- Antidepressants (1)
- DCGAN (1)
- ECG (1)
- FV45 (1)
- GAN (1)
- GI (1)
- Gastrointestinal (1)
- Glomerular filtration (1)
- HFmrEF (1)
- ICD (1)
- MDD (1)
- MPI (1)
- MRI (1)
- Magnetresonanztomografie (1)
- Medullärer Schilddrüsenkrebs (1)
- Myokarditis (1)
- Neuroendocrine (1)
- Neuroendocrine Tumor (1)
- Nierenfunktionsstörung (1)
- Oncology (1)
- PSMA (1)
- PSMA-RADS (1)
- PSMA-RADS-3A (1)
- PSMA-RADS-3B (1)
- PSMA-targeted PET (1)
- Pancreas (1)
- Parkinsonism (1)
- Parkinson’s disease (1)
- Positronenemissionstomografie (1)
- Radionuclide Therapy (1)
- SPECT/CT (1)
- SSTR-PET (1)
- Single-Photon-Emissions-Computertomographie (1)
- Standardisierung (1)
- TKI (1)
- ZDF rats (1)
- [68Ga]DOTATOC (1)
- \(^{18}\)F-FDG (1)
- \(^{18}\)F-fluorodeoxyglucose (1)
- angiotensin II type 1 receptor (1)
- antidepressant (1)
- arrhythmia (1)
- artificial intelligence (1)
- cardiac innervation imaging (1)
- cardiac nerve (1)
- cardiac sympathetic nerve system (1)
- cardiac sympathetic nervous system (1)
- coronary artery disease (1)
- depression (1)
- diabetes (1)
- diabetic cardiomyopathy (1)
- heart failure (1)
- heart failure with mid-range ejection fraction (1)
- hydroxyephedrine (1)
- implants (1)
- inflammation (1)
- interobserver (1)
- interreader (1)
- machine learning (1)
- magnetic resonance imaging (1)
- major depressive disorder (1)
- moycardial sympathetic innervation (1)
- myocardial nerve (1)
- myocardial perfusion imaging (1)
- myocarditis (1)
- pancreas (1)
- peptide receptor radionuclide therapy (1)
- phaeochromocytoma (1)
- preclinical research (1)
- prostate-specific membrane antigen (1)
- prostate-specific membrane antigen (PSMA) (1)
- quantification (1)
- renal failure (1)
- renin-angiotensin system (1)
- reporting and data system (1)
- reporting and data systems (1)
- single photon emission computed tomography: sympathetic nerve (1)
- somatostatin receptor (SSTR) (1)
- spinal cord injury (1)
- standardization (1)
- storage vesicle turnover (1)
- stroke (1)
- sympathetic nervous system (1)
- unilateral ureteral obstruction (1)
- valsartan (1)
Institute
- Klinik und Poliklinik für Nuklearmedizin (29)
- Institut für Anatomie und Zellbiologie (3)
- Medizinische Klinik und Poliklinik I (3)
- Medizinische Klinik und Poliklinik II (3)
- Institut für Pharmakologie und Toxikologie (1)
- Institut für Pharmazie und Lebensmittelchemie (1)
- Klinik und Poliklinik für Psychiatrie, Psychosomatik und Psychotherapie (1)
- Neurologische Klinik und Poliklinik (1)
Sonstige beteiligte Institutionen
- Johns Hopkins School of Medicine (15)
- Johns Hopkins University School of Medicine (5)
- Department of Biomedical Imaging, National Cerebral and Cardiovascular Research Center, Suita, Japan (2)
- Division of Medical Technology and Science, Department of Medical Physics and Engineering, Course of Health Science, Osaka University Graduate School of Medicine, Suita Japan (2)
- Institut for Molecular Biology and CMBI, Department of Genomics, Stem Cell Biology and Regenerative Medicine, Leopold-Franzens-University Innsbruck, Innsbruck, Austria (2)
- Johns Hopkins School of Medicine, The Russell H Morgan Department of Radiology and Radiological Science, Baltimore, MD, USA (2)
- Department of Nuclear Medicine, Kanazawa University (1)
- Johns Hopkins Medicine (1)
- Johns Hopkins School of Medicine, Baltimore, MD, USA (1)
- Johns Hopkins University, Baltimore, MD, U.S. (1)
EU-Project number / Contract (GA) number
- 701983 (29)
As a scintigraphic approach evaluating cardiac nerve integrity, \(^{123}\)I-metaiodobenzylguanidine (123I-mIBG) has been recently Food and Drug Administration approved. A great deal of progress has been made by the prospective ADMIRE-HF trial, which primarily demonstrated the association of denervated myocardium assessed by \(^{123}\)I-mIBG and cardiac events. However, apart from risk stratification, myocardial nerve function evaluated by molecular imaging should also be expanded to other clinical contexts, in particular to guide the referring cardiologist in selecting appropriate candidates for specific therapeutic interventions. In the present issue of the Journal of Nuclear Cardiology, the use of 123I-mIBG for identifying cardiomyopathy patients, which would most likely not benefit from ICD due low risk of arrhythmias, is described. If we aim to deliver on the promise of cardiac innervation imaging as a powerful tool for risk stratification in a manner similar to nuclear oncology, studies such as the one reviewed here may imply an important step to lay the proper groundwork for a more widespread adoption in clinical practice.