Cardioventilatory effects of TRH in anesthetized rats: role of the brainstem
Please always quote using this URN: urn:nbn:de:bvb:20-opus-63277
- Cardioventilator responses were studied in anaesthetized rats after injections of TRH into either the lateral (i.c.v. lat) or the fourth (i.c.v. IV) cerebral ventricles. TRH induced a morerapid hypertensive effect i.c.v. IV than i.c.v. lat. Blocking of the cerebral aqueduct abolished the hypertensive and tachypnoeic effects of TRH i.c.v. lat but not those of TRH i.c.v. IV. It is concluded that TRH increased blood pressure and ventilation rate via brain stem structures close to the fourtli ventricle.
Author: | I. Paakkari, M-L. Nurminen, Anna-Leena Sirén |
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URN: | urn:nbn:de:bvb:20-opus-63277 |
Document Type: | Journal article |
Faculties: | Medizinische Fakultät / Neurochirurgische Klinik und Poliklinik |
Language: | English |
Year of Completion: | 1986 |
Source: | In: European Journal of Pharmacology (1986) 122, 131-134. |
Dewey Decimal Classification: | 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit |
GND Keyword: | Neurobiologie |
Tag: | Brain stem; Cardiovascular; TRH; Ventilation |
Release Date: | 2012/08/09 |
Licence (German): | Deutsches Urheberrecht |