Fluorinated Aryl Boronates as Building Blocks in Organic Synthesis
Please always quote using this URN: urn:nbn:de:bvb:20-opus-225908
- Organoboron compounds are well known building blocks for many organic reactions. However, under basic conditions, polyfluorinated aryl boronic acid derivatives suffer from instability issues that are accelerated in compounds containing an ortho‐fluorine group, which result in the formation of the corresponding protodeboronation products. Therefore, a considerable amount of research has focused on novel methodologies to synthesize these valuable compounds while avoiding the protodeboronation issue. This review summarizes the latest developmentsOrganoboron compounds are well known building blocks for many organic reactions. However, under basic conditions, polyfluorinated aryl boronic acid derivatives suffer from instability issues that are accelerated in compounds containing an ortho‐fluorine group, which result in the formation of the corresponding protodeboronation products. Therefore, a considerable amount of research has focused on novel methodologies to synthesize these valuable compounds while avoiding the protodeboronation issue. This review summarizes the latest developments in the synthesis of fluorinated aryl boronic acid derivatives and their applications in cross‐coupling reactions and other transformations. image…
Author: | Yudha P. Budiman, Stephen A. Westcott, Udo Radius, Todd B. Marder |
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URN: | urn:nbn:de:bvb:20-opus-225908 |
Document Type: | Journal article |
Faculties: | Fakultät für Chemie und Pharmazie / Institut für Anorganische Chemie |
Language: | English |
Parent Title (English): | Advanced Synthesis & Catalysis |
Year of Completion: | 2021 |
Volume: | 363 |
Issue: | 9 |
First Page: | 2224 |
Last Page: | 2255 |
Source: | Advanced Synthesis & Catalysis 2021, 363(9):2224–2255. DOI: 10.1002/adsc.202001291 |
DOI: | https://doi.org/10.1002/adsc.202001291 |
Dewey Decimal Classification: | 5 Naturwissenschaften und Mathematik / 54 Chemie / 540 Chemie und zugeordnete Wissenschaften |
Tag: | boron reagents; boronates; fluorine; fluoroarene; homogeneous catalysis |
Release Date: | 2021/10/14 |
Licence (German): | CC BY: Creative-Commons-Lizenz: Namensnennung 4.0 International |