The role of carcinoembryonic antigen-related cell adhesion molecule 1 in cancer
Please always quote using this URN: urn:nbn:de:bvb:20-opus-357250
- The Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1), also known as CD66a, is a member of the immunoglobulin superfamily. CEACAM1 was shown to be a prognostic marker in patients suffering from cancer. In this review, we summarize pre-clinical and clinical evidence linking CEACAM1 to tumorigenicity and cancer progression. Furthermore, we discuss potential CEACAM1-based mechanisms that may affect cancer biology.
| Author: | Lisa Götz, Uwe Rueckschloss, Gözde Balk, Verena Pfeiffer, Süleyman Ergün, Florian Kleefeldt |
|---|---|
| URN: | urn:nbn:de:bvb:20-opus-357250 |
| Document Type: | Journal article |
| Faculties: | Medizinische Fakultät / Institut für Anatomie und Zellbiologie |
| Language: | English |
| Parent Title (English): | Frontiers in Immunology |
| Year of Completion: | 2023 |
| Volume: | 14 |
| Article Number: | 1295232 |
| Source: | Frontiers in Immunology (2023) 14:1295232. https://doi.org/10.3389/fimmu.2023.1295232 |
| DOI: | https://doi.org/10.3389/fimmu.2023.1295232 |
| Dewey Decimal Classification: | 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit |
| Tag: | CEA; CEACAM1; cancer; malignancy; metastasis; signaling; tumor |
| Release Date: | 2024/05/31 |
| Licence (German): |  CC BY: Creative-Commons-Lizenz: Namensnennung 4.0 International |