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Proposal of a comprehensive definition of modified and other forms of mycotoxins including “masked” mycotoxins
Please always quote using this URN: urn:nbn:de:bvb:20-opus-121240
- As the term "masked mycotoxins" encompasses only conjugated mycotoxins generated by plants and no other possible forms of mycotoxins and their modifications, we hereby propose for all these forms a systematic definition consisting of four hierarchic levels. The highest level differentiates the free and unmodified forms of mycotoxins from those being matrix-associated and from those being modified in their chemical structure. The following lower levels further differentiate, in particular, "modified mycotoxins" into "biologically modified" andAs the term "masked mycotoxins" encompasses only conjugated mycotoxins generated by plants and no other possible forms of mycotoxins and their modifications, we hereby propose for all these forms a systematic definition consisting of four hierarchic levels. The highest level differentiates the free and unmodified forms of mycotoxins from those being matrix-associated and from those being modified in their chemical structure. The following lower levels further differentiate, in particular, "modified mycotoxins" into "biologically modified" and "chemically modified" with all variations of metabolites of the former and dividing the latter into "thermally formed" and "non-thermally formed" ones. To harmonize future scientific wording and subsequent legislation, we suggest that the term "modified mycotoxins" should be used in the future and the term "masked mycotoxins" to be kept for the fraction of biologically modified mycotoxins that were conjugated by plants.…
Author: | Michael Rychlik, Hans-Ulrich Humpf, Doris Marko, Sven Dänicke, Angela Mally, Franz Berthiller, Horst Klaffke, Nicole Lorenz |
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URN: | urn:nbn:de:bvb:20-opus-121240 |
Document Type: | Journal article |
Faculties: | Medizinische Fakultät / Institut für Pharmakologie und Toxikologie |
Language: | English |
Parent Title (English): | Mycotoxin Research |
Year of Completion: | 2014 |
Volume: | 30 |
Issue: | 4 |
Pagenumber: | 197-205 |
Source: | Mycotoxin Research (2014) 30:197–205 DOI 10.1007/s12550-014-0203-5 |
DOI: | https://doi.org/10.1007/s12550-014-0203-5 |
Pubmed Id: | https://pubmed.ncbi.nlm.nih.gov/24962446 |
Dewey Decimal Classification: | 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit |
Tag: | conjugated mycotoxins; definition; hidden mycotoxins; masked mycotoxins; modified mycotoxins; mycotoxin derivates; mycotoxin metabolites; mycotoxins |
Release Date: | 2016/02/18 |
Licence (German): | CC BY: Creative-Commons-Lizenz: Namensnennung |