Journey of a patient with chronic thromboembolic pulmonary hypertension
Please always quote using this URN: urn:nbn:de:bvb:20-opus-125009
- Right ventricle (RV) dysfunction is a key outcome determinant and a leading cause of death for patients with chronic thromboembolic pulmonary hypertension (CTEPH). In this report, we followed the 5-year clinical journey of a patient with CTEPH. The tricuspid pressure gradient was significantly increased in the early phase of CTEPH and “normalized” at the late phase of this patient’s clinical journey, but this “normalized” gradient is not a positive treatment response but rather an ominous sign of advancing right heart failure owing to anRight ventricle (RV) dysfunction is a key outcome determinant and a leading cause of death for patients with chronic thromboembolic pulmonary hypertension (CTEPH). In this report, we followed the 5-year clinical journey of a patient with CTEPH. The tricuspid pressure gradient was significantly increased in the early phase of CTEPH and “normalized” at the late phase of this patient’s clinical journey, but this “normalized” gradient is not a positive treatment response but rather an ominous sign of advancing right heart failure owing to an exhaustion of RV contractile function. Thus, appropriate interpretation of the tricuspid pressure gradient change is of importance for assessing RV dysfunction and treatment outcome during follow-up in patients with CTEPH. Besides systolic pulmonary artery pressure (SPAP), other RV functional parameters such as tricuspid annular plane systolic excursion, RV fractional area change, and RV longitudinal strain, together with clinical markers, may provide additional guidance regarding functional improvement or progression in patients with CTEPH.…
Author: | Dan Liu, Kai Hu, Heinz-Theo Pelzer, Stefan Störk, Frank Weidemann |
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URN: | urn:nbn:de:bvb:20-opus-125009 |
Document Type: | Journal article |
Faculties: | Medizinische Fakultät / Medizinische Klinik und Poliklinik I |
Language: | English |
Parent Title (English): | European Journal of Medical Research |
Year of Completion: | 2015 |
Volume: | 20 |
Issue: | 20 |
Source: | European Journal of Medical Research (2015) 20:20 DOI 10.1186/s40001-015-0112-x |
DOI: | https://doi.org/10.1186/s40001-015-0112-x |
Dewey Decimal Classification: | 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit |
Tag: | chronic thromboembolic pulmonary hypertension; tricuspid pressure gradient |
Release Date: | 2016/02/02 |
Collections: | Open-Access-Publikationsfonds / Förderzeitraum 2015 |
Licence (German): | CC BY: Creative-Commons-Lizenz: Namensnennung |